Výsledky vyhledávání - "JIAN-JIA CAO"

YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells

Autor: Delin Wang, Wen-Bin Li, Xia Sheng, Jiang He, Jian‑Jia Cao, Chao Yu, Wu‑Jiang Liu, Mei‑Cai Li, Zhao Luo, Ke‑Hong Chen

Publikováno v: Molecular Medicine Reports

Yes-associated protein 65 (YAP65) has been implicated as an oncogene, and its expression is increased in human cancer. Previous studies have demonstrated that alterations in YAP activity may result in tumourigenesis of the prostate. With androgen dep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e73a338c6d50297067750dcefe51a3
https://doi.org/10.3892/mmr.2015.4005

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Methylation-associated inactivation of LATS1 and its effect on demethylation or overexpression on YAP and cell biological function in human renal cell carcinoma

Autor: Wen-Bin Li, Wu‑Jiang Liu, Jian‑Jia Cao, Ke‑Hong Chen, Delin Wang, Xia Sheng, Xiu‑Min Zhao, Jiang He, Mei‑Cai Li

Publikováno v: International Journal of Oncology. 45:2511-2521

Large tumor suppressor 1 (LATS1) gene is one of the key factors in Hippo signaling pathway. Inactivation of LATS1 by promoter methylation was found in colorectal cancer (CRC), head and neck squamous cell carcinoma (HNSCC), astrocytoma, breast cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cce20aa2773657b9d14823e4fe336c5
https://doi.org/10.3892/ijo.2014.2687

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YAP is overexpressed in clear cell renal cell carcinoma and its knockdown reduces cell proliferation and induces cell cycle arrest and apoptosis

Autor: Ke-Hong Chen, Meicai Li, Wen-Bin Li, Jiang He, Jian-Jia Cao, Wujiang Liu, Delin Wang, Xiu-Min Zhao, Xia Sheng

Publikováno v: Oncology Reports. 32:1594-1600

Yes-associated protein (YAP) has been reported to be an oncogene in a number of malignancies. It constitutes an important regulatory mechanism for the Hippo pathway, a key regulator of cell growth and apoptosis. The present study aimed to investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00aa0fbb498ae43ffb0455f7993d303a
https://doi.org/10.3892/or.2014.3349

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Isolation and enrichment of PC-3 prostate cancer stem-like cells using MACS and serum-free medium

Autor: Jian-Jia Cao, Zhao Luo, Wen-Bin Li, Chao Yu, Delin Wang, Ke-Hong Chen, Xia Sheng, Wujiang Liu, Zeng Li

Publikováno v: Oncology Letters

Prostate cancer stem-like cells (PCSLCs) are considered to be the ‘seed’ of prostate cancer. The aim of this study was to confirm that the PC-3 cells, which we isolated and enriched from PC-3 cells through magnetic bead cell sorting (MACS) and se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2de3b9c145c2b6d14e8b9a7db8e3c2e
https://pubmed.ncbi.nlm.nih.gov/23426586

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