Zobrazeno 1 - 10
of 34 913
pro vyhledávání: '"JIAN ZHANG"'
Autor:
Xinyuan Zhou, Liwei Zhou, Fengcui Qian, Jiaxin Chen, Yuexin Zhang, Zhengmin Yu, Jian Zhang, Yongsan Yang, Yanyu Li, Chao Song, Yuezhu Wang, Desi Shang, Longlong Dong, Jiang Zhu, Chunquan Li, Qiuyu Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1877-1885 (2024)
Transcription factors (TFs) are major contributors to gene transcription, especially in controlling cell-specific gene expression and disease occurrence and development. Uncovering the relationship between TFs and their target genes is critical to un
Externí odkaz:
https://doaj.org/article/bba1ce15c5c34469894748eb52e542f9
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 162-169 (2024)
AbstractContext Jian Gan powder (JGP) is a Chinese medicine compound comprised ginseng, Radix Paeoniae Alba, Radix Astragali, Salvia miltiorrhiza, Yujin, Rhizoma Cyperi, Fructus aurantii, Sophora flavescens, Yinchen, Bupleurum and licorice.Objective
Externí odkaz:
https://doaj.org/article/684bf09af02e425f94ee6eb855e3834a
Autor:
Lin Wang, Yidan Qin, Jia Song, Jing Xu, Wei Quan, Hang Su, Huibin Zeng, Jian Zhang, Jia Li, Jiajun Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by an insidious onset. Despite the emphasis on motor symptom-based diagnosis, there remains an unmet clinical need for effective diagnostic approaches durin
Externí odkaz:
https://doaj.org/article/b6bf45cb6b4d4aa09037e0f88b52e9e1
Autor:
Yixiang Ruan, Chenyin Lu, Ning Xu, Yuchen He, Yixin Chen, Jian Zhang, Jun Xuan, Jianzhang Pan, Qun Fang, Hanyu Gao, Xiaodong Shen, Ning Ye, Qiang Zhang, Yiming Mo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The rapid emergence of large language model (LLM) technology presents promising opportunities to facilitate the development of synthetic reactions. In this work, we leveraged the power of GPT-4 to build an LLM-based reaction development fram
Externí odkaz:
https://doaj.org/article/79f16f538fb04daeae430f83d0064274
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-8 (2024)
Abstract In response to westward subduction of the Paleo-Pacific, the North China Craton experienced the uplift of an eastern coastal plateau followed by subsidence in the Early Cretaceous, which potentially drove a shift in climatic patterns. Here w
Externí odkaz:
https://doaj.org/article/f32a2c164bc345fabee5f9fce51d064c
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Objective This study aims to explore the regulatory mechanisms of Wnt signaling in the invasion and recurrence of ameloblastoma (AM) to provide a new theoretical basis for its treatment. Methods Bulk RNA sequencing was employed to analyze sa
Externí odkaz:
https://doaj.org/article/f00125ede0e64366ad2e6b840cd2b7c3
Publikováno v:
Defence Technology, Vol 41, Iss , Pp 104-118 (2024)
The load-bearing capacity of reinforced concrete (RC) beams primarily relies on internal reinforced bars. However, limited research has been conducted on the dynamic response of these bars. To address this gap, this study has established an analytica
Externí odkaz:
https://doaj.org/article/a2fb591e73ba4a8b910cd433f1fef2af
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The type IV secretion system is widely present in various bacteria, such as Salmonella, Escherichia coli, and Helicobacter pylori. These bacteria use the type IV secretion system to secrete type IV secretion effectors, infect host
Externí odkaz:
https://doaj.org/article/b1367ebe29bb48479c6a8cf5490aa81c
Autor:
Zhenglei Yu, Jian Zhang, Xin Liu, Chunling Mao, Panpan Li, Qingyang Wang, Kongyuan Yang, Haojie Chi, Zezhou Xu, Fei Cheng, Yunting Guo, Yingchao Xu, Luquan Ren
Publikováno v:
Journal of Materials Research and Technology, Vol 33, Iss , Pp 4884-4898 (2024)
The 7075 Al alloy fabricated using laser powder bed fusion (L-PBF) technology exhibits coarse columnar grains and significant thermal cracking, which hinders it from meeting mechanical and corrosion resistance standards. In this study, 2 wt% micron-s
Externí odkaz:
https://doaj.org/article/79bc4bdb8d444133b82069c6d01b3d00
Autor:
Ethan A. Older, Jian Zhang, Zachary E. Ferris, Dan Xue, Zheng Zhong, Mary K. Mitchell, Michael Madden, Yuzhen Wang, Hexin Chen, Prakash Nagarkatti, Mitzi Nagarkatti, Daping Fan, Melissa Ellermann, Yong-Xin Li, Jie Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The trillions of microorganisms inhabiting the human gut are intricately linked to human health. While specific microbes have been associated with diseases, microbial abundance alone cannot reveal the molecular mechanisms involved. One such
Externí odkaz:
https://doaj.org/article/610f9c86477c44328236ec90fbbd6581