Zobrazeno 1 - 10
of 3 167
pro vyhledávání: '"JIA Fan"'
Autor:
Zheng-Jun Zhou, Yu-Hang Ye, Zhi-Qiang Hu, Yue-Ru Hou, Kai-Xuan Liu, Rong-Qi Sun, Peng-Cheng Wang, Chu-Bin Luo, Jia Li, Ji-Xue Zou, Jian Zhou, Jia Fan, Cheng-Li Song, Shao-Lai Zhou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Intrahepatic cholangiocarcinoma (ICC) is the second most common primary hepatic malignancy after hepatocellular carcinoma, with poor prognosis and limited treatment options. The genomic features of ICC in Chinese patients remain largely unkn
Externí odkaz:
https://doaj.org/article/f160d77c00784481bb1719f4a23c13cf
Autor:
Jialiang Cai, Lina Song, Feng Zhang, Suiyi Wu, Guiqi Zhu, Peiling Zhang, Shiping Chen, Junxian Du, Biao Wang, Yufan Cai, Yi Yang, Jinglei Wan, Jian Zhou, Jia Fan, Zhi Dai
Publikováno v:
Cancer Communications, Vol 44, Iss 11, Pp 1231-1260 (2024)
Abstract Background The efficacy of immune checkpoint blockade therapy in patients with hepatocellular carcinoma (HCC) remains poor. Although serine‐ and arginine‐rich splicing factor (SRSF) family members play crucial roles in tumors, their impa
Externí odkaz:
https://doaj.org/article/43d701a4f6b24ef59b4dd2e4aed02f03
Autor:
Xiaojia Wen, Yu Lu, Yanming Li, Peijing Qi, Ying Wu, Jiaole Yu, Ruidong Zhang, Qian Huang, Pengli Huang, Bei Hou, Jie Yang, Mengjia Liu, Huiqing Liu, Hongqiao Li, Ning Sun, Yanni Zhang, Yuanyuan Zhang, Wei Lin, Jia Fan, Yan Liu, Huyong Zheng
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract The efficacy and safety of venetoclax in newly diagnosed pediatric acute myeloid leukemia (AML) are not well-established as they are in adults. Children newly diagnosed with AML were recommended for induction therapy with venetoclax and chem
Externí odkaz:
https://doaj.org/article/b0d38d7d49534ff5bdf4dfad77f9463d
Autor:
Yu-Hang Ye, Hao-Yang Xin, Jia-Li Li, Ning Li, Si-Yuan Pan, Long Chen, Jing-Yue Pan, Zhi-Qiang Hu, Peng-Cheng Wang, Chu-Bin Luo, Rong-Qi Sun, Jia Fan, Jian Zhou, Zheng-Jun Zhou, Shao-Lai Zhou
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 4, Pp 914-928 (2024)
Backgrounds/Aims Intrahepatic cholangiocarcinoma (ICC) is a highly desmoplastic tumor with poor prognosis even after curative resection. We investigated the associations between the composition of the ICC stroma and immune cell infiltration and aimed
Externí odkaz:
https://doaj.org/article/7491acc445a24cdc863468dd21087b0c
Publikováno v:
Zhongguo Linchuang Yixue, Vol 31, Iss 5, Pp 691-695 (2024)
With rapid development and maturity of single-cell measurements, single-cell biology and pathology has become an emerging discipline to understand the disease. However, it is important to address concerns raised by clinicians as to how to apply singl
Externí odkaz:
https://doaj.org/article/80061ec8f57f44eea654484b2531ffee
Autor:
Dao-Han Zhang, Chen Liang, Shu-Yang Hu, Xiao-Yong Huang, Lei Yu, Xian-Long Meng, Xiao-Jun Guo, Hai-Ying Zeng, Zhen Chen, Lv Zhang, Yan-Zi Pei, Mu Ye, Jia-Bin Cai, Pei-Xin Huang, Ying-Hong Shi, Ai-Wu Ke, Yi Chen, Yuan Ji, Yujiang Geno Shi, Jian Zhou, Jia Fan, Guo-Huan Yang, Qi-Man Sun, Guo-Ming Shi, Jia-Cheng Lu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Single-cell technology depicts integrated tumor profiles including both tumor cells and tumor microenvironments, which theoretically enables more robust diagnosis than traditional diagnostic standards based on only pathology. However, the in
Externí odkaz:
https://doaj.org/article/e9d2b0231e9149bfa667fd275a856f8c
Publikováno v:
hLife, Vol 2, Iss 9, Pp 439-453 (2024)
Hepatocellular carcinoma (HCC) is a significant global health challenge, requiring innovative methods to improve patient survival. Due to different disease backgrounds, different HCC management guidelines have been developed, especially in the field
Externí odkaz:
https://doaj.org/article/b89eca1ebf41420fbf9f668d6e52a433
Autor:
Qing Chen, Dan Yin, Yong Zhang, Lei Yu, Xue-Dong Li, Zheng-Jun Zhou, Shao-Lai Zhou, Dong-Mei Gao, Jie Hu, Cheng Jin, Zheng Wang, Ying-Hong Shi, Ya Cao, Jia Fan, Zhi Dai, Jian Zhou
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/3828396a5fda4fa29c21c9aea0dc822f
Autor:
De-Zhen Guo, Xin Zhang, Sen-Quan Zhang, Shi-Yu Zhang, Xiang-Yu Zhang, Jia-Yan Yan, San-Yuan Dong, Kai Zhu, Xin-Rong Yang, Jia Fan, Jian Zhou, Ao Huang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Background Tumor heterogeneity presents a formidable challenge in understanding the mechanisms driving tumor progression and metastasis. The heterogeneity of hepatocellular carcinoma (HCC) in cellular level is not clear. Methods Integration
Externí odkaz:
https://doaj.org/article/5bab73eed7a64bc1ad8a6db34ea7804a
Autor:
Guang-Yu Ding, Wei-Min Tan, You-Pei Lin, Yu Ling, Wen Huang, Shu Zhang, Jie-Yi Shi, Rong-Kui Luo, Yuan Ji, Xiao-Ying Wang, Jian Zhou, Jia Fan, Mu-Yan Cai, Bo Yan, Qiang Gao
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background The advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains a significant barrier to clinical application. Methods We establ
Externí odkaz:
https://doaj.org/article/87c9a85be43548f8b4e6ba684603012f