Abstract P5-15-04: The PROCEED trial KCSG BR11-01 phase III multicenter randomized open-label study of irinotecan plus capecitabine versus capecitabine in patients previously treated with anthracycline and taxane for HER2 negative metastatic breast cancer

Autor: IH Park, S-A Im, KH Jung, JH Sohn, YH Park, K-H Park, B-H Nam, JH Kim, H-J Kim, S Lee, T-Y Kim, K-H Lee, S-B Kim, KS Lee, J Ro

Publikováno v: Cancer Research. 77:P5-15

Purpose We investigated whether the combination of irinotecan plus capecitabine improved progression free survival (PFS) compared with capecitabine alone in patients with HER2 negative MBC previously exposed to anthracyclines and taxanes. Patients an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbb9f0aef43164b9b405fca2d137b94a
https://doi.org/10.1158/1538-7445.sabcs16-p5-15-04

Chondroitin Sulfate-Based Biocompatible Crosslinker Restores Corneal Mechanics and Collagen Alignment

Autor: Deepak P. Edward, Garret Ma, Samuel C Yiu, Walter J. Stark, Jennifer H. Elisseeff, Shoumyo Majumdar, Awad Al-Qarni, JH Sohn, Xiaokun Wang

Publikováno v: Investigative ophthalmologyvisual science. 58(10)

Purpose To evaluate the crosslinking effect of functionalized chondroitin sulfate (CS) in an ex vivo rabbit cornea model. Methods Chondroitin sulfate molecules were chemically modified with the N-hydroxysuccinimide (NHS) group. Enucleated rabbit eyes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236ebf4bc6786e5894d3ca8ee9a222bf
https://pubmed.ncbi.nlm.nih.gov/28763562

The 20th Conference of the Asian Pacific Association for the Study of the Liver Poster Presentation

Autor: SW Paik, JH Sohn, YO Kweon, Rmf Yuen, K Lee, Doo-Man Kim, T Piratvisuth, A Trylesinski, SH Ahn, C Avila

Publikováno v: Hepatology International

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d1fcca00c49600914202b0a178d6a0
https://doi.org/10.1007/s12072-010-9169-3

Functional expression of recombinant insulins in Saccharomyces cerevisiae.

Autor: Kim MJ; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-Ro, Yuseong-Gu, Daejeon, 34141, Republic of Korea., Park SL; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-Ro, Yuseong-Gu, Daejeon, 34141, Republic of Korea., Kim HJ; Cellapy Bio Inc. Bio-Venture Center, #211, 125 Gwahak-Ro, Yuseong-Gu, Daejeon, 34141, Republic of Korea., Sung BH; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-Ro, Yuseong-Gu, Daejeon, 34141, Republic of Korea., Sohn JH; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-Ro, Yuseong-Gu, Daejeon, 34141, Republic of Korea. sohn4090@kribb.re.kr.; Cellapy Bio Inc. Bio-Venture Center, #211, 125 Gwahak-Ro, Yuseong-Gu, Daejeon, 34141, Republic of Korea. sohn4090@kribb.re.kr., Bae JH; Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-Ro, Yuseong-Gu, Daejeon, 34141, Republic of Korea. hoon@kribb.re.kr.

Publikováno v: Microbial cell factories [Microb Cell Fact] 2024 Nov 11; Vol. 23 (1), pp. 302. Date of Electronic Publication: 2024 Nov 11.

Small molecules targeting selective PCK1 and PGC-1α lysine acetylation cause anti-diabetic action through increased lactate oxidation.

Autor: Mutlu B; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Sharabi K; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA; Institute of Biochemistry, Food Science and Nutrition, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Jerusalem, Israel., Sohn JH; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Yuan B; Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA., Latorre-Muro P; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Qin X; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Yook JS; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA., Lin H; Department of Molecular Medicine, The Wertheim UF Scripps Institute for Biomedical Innovation and Technology, University of Florida, Jupiter, FL 33458, USA., Yu D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA., Camporez JPG; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520-8020, USA; Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06520-8020, USA., Kajimura S; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Chevy Chase, MD 020815, USA., Shulman GI; Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520-8020, USA; Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06520-8020, USA; Howard Hughes Medical Institute, Chevy Chase, MD 020815, USA., Hui S; Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA., Kamenecka TM; Department of Molecular Medicine, The Wertheim UF Scripps Institute for Biomedical Innovation and Technology, University of Florida, Jupiter, FL 33458, USA., Griffin PR; Department of Molecular Medicine, The Wertheim UF Scripps Institute for Biomedical Innovation and Technology, University of Florida, Jupiter, FL 33458, USA., Puigserver P; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02215, USA. Electronic address: pere_puigserver@dfci.harvard.edu.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2024 Oct 17; Vol. 31 (10), pp. 1772-1786.e5. Date of Electronic Publication: 2024 Sep 27.