Zobrazeno 1 - 10
of 103
pro vyhledávání: '"JEFFREY R. BALSER"'
Publikováno v:
Confluence of Policy and Leadership in Academic Health Science Centers ISBN: 9781846198786
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae6572d4f80c81329d62194c18344a22
https://doi.org/10.1201/9781846198786-4
https://doi.org/10.1201/9781846198786-4
Autor:
Jeffrey R. Balser
Publikováno v:
Consulting Psychology Journal: Practice and Research. 71:165-169
Autor:
Jonathan B. Perlin, Bruce Siegel, Jaewon Ryu, Jeffrey R. Balser, Gary S. Kaplan, M. Michelle Hood
Publikováno v:
NAM Perspect
Autor:
Jeffrey R, Balser, William W, Stead
Publikováno v:
Transactions of the American Clinical and Climatological Association. 128
Academic health centers (AHCs) are the nation’s primary resource for healthcare discovery, innovation, and training. US healthcare revenue growth has declined sharply since 2009, and is forecast to remain well below historic levels for the foreseea
Autor:
Corey R. Hopkins, Sabina Kupershmidt, Sebastien Chaigne, Svetlana Z. Stepanovic, Jeffrey R. Balser, Alfred L. George, Franck Potet, Amanda Lorinc, Craig W. Lindsley, David Afshartous, Darren W. Engers, L. Michelle Lewis, Franz J. Baudenbacher, Veniamin Y. Sidorov, Courtney M. Campbell, Min Li, Beiyan Zou, C. David Weaver, Emily Days, Raghav Venkataraman
Publikováno v:
Journal of Biological Chemistry. 287:39613-39625
The human Ether-à-go-go-related gene (hERG)-encoded K(+) current, I(Kr) is essential for cardiac repolarization but is also a source of cardiotoxicity because unintended hERG inhibition by diverse pharmaceuticals can cause arrhythmias and sudden car
Autor:
Jens Meiler, Sabina Kupershmidt, Jeffrey R. Balser, Christina I. Petersen, Jarrod A. Smith, Svetlana Z. Stepanovic, Franck Potet
Publikováno v:
The Journal of Physiology. 587:2555-2566
Human ether-a-go-go-related gene (HERG) encodes the rapid, outwardly rectifying K+ current IKr that is critical for repolarization of the cardiac action potential. Congenital HERG mutations or unintended pharmaceutical block of IKr can lead to life-t
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (10), pp.6436-6445. ⟨10.1074/jbc.M807747200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (10), pp.6436-6445. ⟨10.1074/jbc.M807747200⟩
The voltage-gated sodium channel NaV1.5 is responsible for the initial upstroke of the action potential in cardiac tissue. Levels of intracellular calcium modulate inactivation gating of NaV1.5, in part through a C-terminal EF-hand calcium binding do
Autor:
Walter J. Chazin, Jeffrey R. Balser, Prakash C. Viswanathan, Sabina Kupershmidt, Svetlana Z. Stepanovic, Benjamin Chagot, Mircea Anghelescu, Franck Potet
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (13), pp.8846-8854. ⟨10.1074/jbc.M806871200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, 284 (13), pp.8846-8854. ⟨10.1074/jbc.M806871200⟩
Sodium channels are fundamental signaling molecules in excitable cells, and are molecular targets for local anesthetic agents and intracellular free Ca(2+) ([Ca(2+)](i)). Two regions of Na(V)1.5 have been identified previously as [Ca(2+)](i)-sensitiv
Autor:
Franck Potet, Jeffrey R. Balser, Wen Shuai, Svetlana Z. Stepanovic, Sabina Kupershmidt, Christina I. Petersen, Olivier Boutaud
Publikováno v:
Journal of Molecular and Cellular Cardiology. 46:257-267
The human ether-a-go-go related gene (HERG) constitutes the pore forming subunit of I(Kr), a K(+) current involved in repolarization of the cardiac action potential. While mutations in HERG predispose patients to cardiac arrhythmias (Long QT syndrome
Autor:
Lee E. Limbird, Abigail M. Brown, Daniel W. Byrne, Steven G. Gabbe, Nancy J. Brown, Jeffrey R. Balser, Jason D. Morrow
Publikováno v:
Academic Medicine. 83:969-975
Advances in biomedical science today provide an unprecedented opportunity to improve human health. The translation of scientific and technological advances into better health requires the training of physician–scientists who are equipped with the s