Zobrazeno 1 - 10
of 214
pro vyhledávání: '"JEFFREY A BORGIA"'
Autor:
Kyle D Anderson, Christian Beckmann, Saskia Heermant, Frank C Ko, Bryan Dulion, Imad Tarhoni, Jeffrey A Borgia, Amarjit S Virdi, Markus A Wimmer, D Rick Sumner, Ryan D Ross
Publikováno v:
JBMR Plus, Vol 7, Iss 11, Pp n/a-n/a (2023)
ABSTRACT An increasing number of patients with type 2 diabetes (T2DM) will require total joint replacement (TJR) in the next decade. T2DM patients are at increased risk for TJR failure, but the mechanisms are not well understood. The current study us
Externí odkaz:
https://doaj.org/article/e5de1822a7364e4cb362b8e66e444812
Autor:
Philip Bonomi, Hita Moudgalya, Sandra L. Gomez, Palmi Shah, Sanjib Basu, Marta Batus, Levi B. Martinka, Ahmed Abdelkader, Iphigenia Tzameli, Sonia Cobain, Susie Collins, Edmund J. Keliher, Danna M. Breen, Roberto A. Calle, Mary Jo Fidler, Jeffrey A. Borgia
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 6, Pp 2311-2322 (2024)
Abstract Background The primary objective of this study was to assess the frequency of body composition increases and their relationships to changes in body weight in two cohorts of real world, treatment‐naïve, advanced non‐small cell lung cance
Externí odkaz:
https://doaj.org/article/9783cab46df946fea677b29c1671a54e
Autor:
Ateeq M. Khaliq, Cihat Erdogan, Zeyneb Kurt, Sultan Sevgi Turgut, Miles W. Grunvald, Tim Rand, Sonal Khare, Jeffrey A. Borgia, Dana M. Hayden, Sam G. Pappas, Henry R. Govekar, Audrey E. Kam, Jochen Reiser, Kiran Turaga, Milan Radovich, Yong Zang, Yingjie Qiu, Yunlong Liu, Melissa L. Fishel, Anita Turk, Vineet Gupta, Ram Al-Sabti, Janakiraman Subramanian, Timothy M. Kuzel, Anguraj Sadanandam, Levi Waldron, Arif Hussain, Mohammad Saleem, Bassel El-Rayes, Ameen A. Salahudeen, Ashiq Masood
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-30 (2022)
Abstract Background Colorectal cancer (CRC) consensus molecular subtypes (CMS) have different immunological, stromal cell, and clinicopathological characteristics. Single-cell characterization of CMS subtype tumor microenvironments is required to elu
Externí odkaz:
https://doaj.org/article/ae2d60102a98447596fa9e335944c864
Autor:
Nicholas J. Skertich, MD, Fei Chu, MD, PhD, Imad AM Tarhoni, MD, PhD, Stephen Szajek, MS, Jeffrey A. Borgia, PhD, Mary Beth Madonna, MD
Publikováno v:
Surgery Open Science, Vol 6, Iss , Pp 10-14 (2021)
Background: Inhibition of the programmed death ligand 1, programmed death 1 pathway has been successfully used for treatment of multiple advanced adult cancers. However, its use in pediatric osteosarcoma is still in its infancy. In this study, we inv
Externí odkaz:
https://doaj.org/article/d0d96fadea01498a9d7fba6667923e85
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
BackgroundPlasma cardiac biomarkers have emerged as a cost-effective diagnostic tool aimed at early identification of cardiotoxicity. Soluble urokinase plasminogen activator receptor (suPAR) is a bone marrow cell derived signaling molecule that is as
Externí odkaz:
https://doaj.org/article/6cada3497bd44614b359a128740c4d17
Autor:
Brian M. Larsen, Madhavi Kannan, Lee F. Langer, Benjamin D. Leibowitz, Aicha Bentaieb, Andrea Cancino, Igor Dolgalev, Bridgette E. Drummond, Jonathan R. Dry, Chi-Sing Ho, Gaurav Khullar, Benjamin A. Krantz, Brandon Mapes, Kelly E. McKinnon, Jessica Metti, Jason F. Perera, Tim A. Rand, Veronica Sanchez-Freire, Jenna M. Shaxted, Michelle M. Stein, Michael A. Streit, Yi-Hung Carol Tan, Yilin Zhang, Ende Zhao, Jagadish Venkataraman, Martin C. Stumpe, Jeffrey A. Borgia, Ashiq Masood, Daniel V.T. Catenacci, Jeremy V. Mathews, Demirkan B. Gursel, Jian-Jun Wei, Theodore H. Welling, Diane M. Simeone, Kevin P. White, Aly A. Khan, Catherine Igartua, Ameen A. Salahudeen
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109429- (2021)
Summary: Patient-derived tumor organoids (TOs) are emerging as high-fidelity models to study cancer biology and develop novel precision medicine therapeutics. However, utilizing TOs for systems-biology-based approaches has been limited by a lack of s
Externí odkaz:
https://doaj.org/article/9e05120e2cf8481abf4978520140395c
Autor:
Yuhong Dou, Yong Zhu, Junmei Ai, Hankui Chen, Helu Liu, Jeffrey A. Borgia, Xiao Li, Fan Yang, Bin Jiang, Jun Wang, Youping Deng
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Lung cancer is a major cause of cancer-related mortality worldwide, and around two-thirds of patients have metastasis at diagnosis. Thus, detecting lung cancer at an early stage could reduce mortality. Aberrant levels of circulati
Externí odkaz:
https://doaj.org/article/d2ba930125ce4484b36956df2d6c66e7
Autor:
Mary Jo Fidler, Cristina L. Fhied, Joanna Roder, Sanjib Basu, Selina Sayidine, Ibtihaj Fughhi, Mark Pool, Marta Batus, Philip Bonomi, Jeffrey A. Borgia
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background The VeriStrat test is a serum proteomic signature originally discovered in non-responders to second line gefitinib treatment and subsequently used to predict differential benefit from erlotinib versus chemotherapy in previously tr
Externí odkaz:
https://doaj.org/article/50ebd1b8392c48aa9f668f55a3ffc1c6
Autor:
Connor J, Wakefield, Nicholas, Lund, Julia, Coughlin, Justin M, Karush, Nicole, Geissen, Gillian, Alex, Michael J, Liptay, Jeffrey A, Borgia, Palmi, Shah, Christopher W, Seder
Publikováno v:
Journal of Thoracic Disease. 14:4256-4265
Sarcopenia, as measured at the 3rd lumbar (L3) level, has been shown to prognosticate survival in cancer patients. However, many patients with early-stage non-small cell lung cancer (NSCLC) do not undergo abdominal imaging. We hypothesized that preop
Autor:
Nicolette Jeanblanc, Laurel Jackson, Susan Gawel, Susan Brophy, Shyam Vaidya, Salman Syed, Gerard J Davis, Jeffrey A. Borgia
Publikováno v:
Clinica Chimica Acta. 535:197-202
Early detection of lung cancer allows for earlier stage treatment initiation and improved patient prognosis. This report focuses on utilization of combining patient demographic information with non-invasive biomarkers and their potential ability to p