Zobrazeno 1 - 10
of 293
pro vyhledávání: '"JEFF M. SANDS"'
Autor:
Roxana C. Chicas, Yilin Wang, E. Jennifer Weil, Lisa Elon, Nezahualcoyotl Xiuhtecutli, Madelyn C. Houser, Dean P. Jones, Jeff M. Sands, Vicki Hertzberg, Linda McCauley, Donghai Liang
Publikováno v:
Environment International, Vol 180, Iss , Pp 108206- (2023)
Background: Agricultural workers are consistently exposed to elevated heat exposures and vulnerable to acute kidney injury. The underlying pathophysiology and detailed molecular mechanisms of AKI among agricultural workers, and the disproportionate b
Externí odkaz:
https://doaj.org/article/4f4c6298f8d246d9919117cf6e012e98
Autor:
Yanhua Wang, Lauren M. LaRocque, Joseph A. Ruiz, Eva L. Rodriguez, Jeff M. Sands, Janet D. Klein
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1844 (2023)
Hyponatremia (hypo-osmolality) is a disorder of water homeostasis due to abnormal renal diluting capacity. The body limits the degree to which serum sodium concentration falls through a mechanism called “vasopressin escape”. Vasopressin escape is
Externí odkaz:
https://doaj.org/article/5198fd45c4024b5dabe674b0e5b2153e
Publikováno v:
Molecules, Vol 28, Iss 11, p 4446 (2023)
Detection of erythropoietin (Epo) was difficult until a method was developed by the World Anti-Doping Agency (WADA). WADA recommended the Western blot technique using isoelectric focusing (IEF)-PAGE to show that natural Epo and injected erythropoiesi
Externí odkaz:
https://doaj.org/article/222b398af8554ed08a7072b269486924
Autor:
Janet D. Klein, Ish Khanna, Ram Pillarisetti, Rachael A. Hagan, Lauren M. LaRocque, Eva L. Rodriguez, Jeff M. Sands
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
Nephrogenic diabetes insipidus (NDI) patients produce large amounts of dilute urine. NDI can be congenital, resulting from mutations in the type-2 vasopressin receptor (V2R), or acquired, resulting from medications such as lithium. There are no effec
Externí odkaz:
https://doaj.org/article/3e000dbabb104220804b90dc7a55720c
Publikováno v:
Journal of Clinical and Translational Science, Vol 5 (2021)
Abstract Introduction: The Clinical and Translational Science Awards (CTSA) program of the National Center for Advancing Translational Sciences (NCATS) seeks to improve population health by accelerating the translation of scientific discoveries in t
Externí odkaz:
https://doaj.org/article/e6f7bf2712744a318e12bd89efd26766
Autor:
Yukiko Yasuoka, Takashi Fukuyama, Yuichiro Izumi, Tetsuro Yamashita, Yushi Nakayama, Hideki Inoue, Kengo Yanagita, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Masashi Mukoyama, Yuichi Sato, Jeff M. Sands, Katsumasa Kawahara, Hiroshi Nonoguchi
Publikováno v:
Heliyon, Vol 6, Iss 11, Pp e05389- (2020)
Doping tests for the illegal use of erythropoiesis-stimulating agents (ESAs) have been developed. We developed a new Western blotting method to detect and distinguish endogenous erythropoietin (Epo, 35-38 kDa) and exogenous ESAs (epoetin α and β, 3
Externí odkaz:
https://doaj.org/article/e4e48d4cbd494a719c9eb3d4572c3279
Autor:
Yukiko Yasuoka, Takashi Fukuyama, Yuichiro Izumi, Yushi Nakayama, Hideki Inoue, Kengo Yanagita, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Masashi Mukoyama, Tetsuro Yamashita, Yuichi Sato, Jeff M. Sands, Katsumasa Kawahara, Hiroshi Nonoguchi
Publikováno v:
Physiological Reports, Vol 8, Iss 12, Pp n/a-n/a (2020)
Abstract The detection of erythropoietin (Epo) protein by Western blotting has required pre‐purification of the sample. We developed a new Western blot method to detect plasma and urinary Epo using deglycosylation. Epo in urine and tissue, and eryt
Externí odkaz:
https://doaj.org/article/5ec73d617102476aa3f117aab7606d78
Autor:
Yukiko Yasuoka, Yuichiro Izumi, Takashi Fukuyama, Haruki Omiya, Truyen D. Pham, Hideki Inoue, Tomomi Oshima, Taiga Yamazaki, Takayuki Uematsu, Noritada Kobayashi, Yoshitaka Shimada, Yasushi Nagaba, Tetsuro Yamashita, Masashi Mukoyama, Yuichi Sato, Susan M. Wall, Jeff M. Sands, Noriko Takahashi, Katsumasa Kawahara, Hiroshi Nonoguchi
Publikováno v:
Molecules, Vol 27, Iss 3, p 1119 (2022)
Anemia is a major complication of chronic renal failure. To treat this anemia, prolylhydroxylase domain enzyme (PHD) inhibitors as well as erythropoiesis-stimulating agents (ESAs) have been used. Although PHD inhibitors rapidly stimulate erythropoiet
Externí odkaz:
https://doaj.org/article/454c38365a2d421d94587e564812c29b
Publikováno v:
Cells, Vol 9, Iss 12, p 2533 (2020)
Adrenomedullin (ADM) is a vasodilator that causes natriuresis and diuresis. However, the direct effect of ADM on osmotic water permeability in the rat inner medullary collecting duct (IMCD) has not been tested. We investigated whether ADM and its ADM
Externí odkaz:
https://doaj.org/article/11c03133f4ea4e9c924cd0786c6ff55a
Publikováno v:
Cells, Vol 9, Iss 4, p 967 (2020)
Aldosterone indirectly regulates water reabsorption in the distal tubule by regulating sodium reabsorption. However, the direct effect of aldosterone on vasopressin-regulated water and urea permeability in the rat inner medullary collecting duct (IMC
Externí odkaz:
https://doaj.org/article/9652d6dd0270405e9e21a60163f2e372