Zobrazeno 1 - 10
of 479
pro vyhledávání: '"JE Dixon"'
Publikováno v:
European Cells & Materials, Vol 47, Pp 152-169 (2024)
Traumatic musculoskeletal injuries require advanced therapeutic intervention to heal effectively. Regenerative medicine research has aimed to address this by using biomaterials to deliver gene therapeutic nanoparticles (NPs) to the injury site to dir
Externí odkaz:
https://doaj.org/article/fbc9db1dfb6743f18c91ce00a238ef8a
Publikováno v:
European Cells & Materials, Vol 47, Pp 91-108 (2024)
Articular cartilage (AC) has a poor capacity to repair once damaged, with progressive degeneration often leading to osteoarthritis (OA). While biomaterials fabricated with extra cellular matrix (ECM) native to the AC have shown promise for repair of
Externí odkaz:
https://doaj.org/article/243c755d771d4f9791a0a732ef45c7be
Autor:
VA Brentville, M Vankemmelbeke, RL Metheringham, P Symonds, KW Cook, RA Urbanowicz, T Tsoleridis, CM Coleman, K-C Chang, A Skinner, E Dubinina, I Daniels, S Shah, M Argonza, J Delgado, V Dwivedi, V Kulkarni, JE Dixon, AG Pockley, SE Adams, SJ Paston, JM Daly, JK Ball, LG Durrant
Although the efficacy of vaccines targeting SARS-CoV-2 is apparent now that the approved mRNA and adenovirus vector vaccines are in widespread use, the longevity of the protective immune response and its efficacy against emerging variants remains to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::273049cd8745e311fc379ecc0bdb3904
https://doi.org/10.1101/2021.06.18.448932
https://doi.org/10.1101/2021.06.18.448932
Publikováno v:
Europe PubMed Central
Gene constructs consisting of human growth hormone (hGH) gene driven by promoter/regulatory sequence of mouse metallothionein (mMT), viral thymidine kinase (vTK), rat cholecystokinin (rCCK), or chicken beta-actin (cBA) gene were injected into the cyt
Publikováno v:
Europe PubMed Central
This report describes the cloning and characterization of rat leukocyte common antigen-related protein (rLAR), a receptor-like protein tyrosine phosphatase (PTPase). The recombinant cytoplasmic PTPase domain was expressed at high levels in bacteria a
Publikováno v:
Europe PubMed Central
Soluble proteins which reside in the lumen of the endoplasmic reticulum share a common carboxyl-terminal tetrapeptide Lys-Asp-Glu-Leu (KDEL). Addition of the tetrapeptide to a normally secreted protein is both necessary and sufficient to cause retent
Publikováno v:
Europe PubMed Central
Although pairs of basic amino acids are common endoproteolytic sites in prohormones, the enzymes responsible for these cleavages have not yet been characterized. To investigate the specificity of these endoproteases, cDNAs encoding pro-neuropeptide Y
Publikováno v:
Europe PubMed Central
An expression vector was constructed that placed the cDNA for human neuropeptide Y (NPY) under the control of the mouse metallothionein promoter and was used to transfect the AtT-20 mouse anterior pituitary corticotrope cell line. AtT-20 cells normal
Publikováno v:
Europe PubMed Central
A 43-kDa DNA binding protein which recognizes the TGACGTCA element of the rat somatostatin promoter has been purified from rat brain. Purification of the protein involved initial separation of three sequence-specific binding activities, b1-b3, from e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b0d3073a8a44664582ed5aa7d1dd188c
http://europepmc.org/abstract/med/2564850
http://europepmc.org/abstract/med/2564850
Autor:
Ourania Andrisani, Je, Dixon
Publikováno v:
Europe PubMed Central
The TGACGTCA (CRE) motif required for function by a number of cellular (somatostatin, enkephalin, alpha-human chorionic gonadotropin) and viral (Ad5 E1A-inducible, HTLV-1 TAX-inducible) genes is the site of interaction of multiple sequence-specific c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0a5b94cd60b6898f239b3f79cd658b3a
http://europepmc.org/abstract/med/2137455
http://europepmc.org/abstract/med/2137455