Výsledky vyhledávání

Modulation of spontaneous B-cell differentiation in macroglobulinemia by retinoic acid

Autor: Y Levy, S Labaume, MC Gendron, JC Brouet

Publikováno v: Blood. 83:2206-2210

We previously showed that clonal blood B cells from patients with macroglobulinemia spontaneously differentiate in vitro to plasma cells. This process is dependent on an interleukin (IL)-6 autocrine pathway. We investigate here whether all-trans-reti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46b8e69f659119f3fdbc58120df1736d
https://doi.org/10.1182/blood.v83.8.2206.bloodjournal8382206

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Altered signal transduction secondary to surface IgM cross-linking on B-chronic lymphocytic leukemia cells. Differential activation of the phosphatidylinositol-specific phospholipase C

Autor: Claire Hivroz, Gény B, Jc, Brouet, Grillot-Courvalin C

Publikováno v: Europe PubMed Central

To further study the mechanisms by which surface Ig triggering activates the inositol phospholipid signaling pathway, we have used B cells from chronic lymphocytic leukemia patients which, as previously described, display two patterns of response upo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c6c728a755589a26b41819dc21ca6e6
https://doi.org/10.4049/jimmunol.144.6.2351

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Evaluation of bone mineral density and fat-lean distribution in patients with multiple myeloma in sustained remission

Autor: J Frija, Xavier Mariette, J.-P. Fermand, Sophie Roux, Catherine Bergot, JC Brouet

Publikováno v: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 18(2)

To study the usefulness of bone mineral density (BMD) in the follow-up of myeloma (MM) patients, BMD was evaluated in 44 MM patients in sustained remission for at least 2 years (35.4 +/- 10.5 months) after high-dose or conventional chemotherapy in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266d369690996641c880a88e41b6a64f
https://pubmed.ncbi.nlm.nih.gov/12568400

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[Cost of intensive treatment followed by autograft of circulating stem cells. Application to multiple myeloma]

Autor: Callaert S, Philippe Ravaud, Viens-Bitker C, Dreyfus F, Hazebroucq G, Amor B, Jc, Brouet, Jp, Fermand

Publikováno v: Europe PubMed Central

Legitimate efforts to reduce health care costs, especially of intensive protocols including transplantation for haematological diseases, require realistic economic evaluations. We determined the direct cost of intensive chemotherapy associated with t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eaeac075846b5cf58d9af92c435a21b2
https://pubmed.ncbi.nlm.nih.gov/7915417

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The syndrome of T8 hyperlymphocytosis: variation in phenotype and cytotoxic activities of granular cells and evaluation of their role in associated neutropenia

Autor: C Grillot-Courvalin, G Vinci, A Tsapis, MC Dokhelar, W Vainchenker, JC Brouet

Publikováno v: Blood. 69:1204-1210

We performed a longitudinal study of the phenotype and functions of granular lymphoid cells from seven patients with T8 hyperlymphocytosis and neutropenia. Whereas cells retained a T3+ T8+ (six cases) or T3- T8+ (one case) phenotype at different exam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9996906e1af8b12a84c422b33715371
https://doi.org/10.1182/blood.v69.4.1204.bloodjournal6941204

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Associated chronic lymphocytic leukemia and multiple myeloma: origin from a single clone

Autor: JP Fermand, JM James, P Herait, JC Brouet

Publikováno v: Blood. 66(2)

We investigated the clonal relationship of malignant cells in a patient affected with both chronic lymphocytic leukemia (CLL) and multiple myeloma (MM). CLL cells and malignant plasma cells synthesized IgG1 kappa and IgA kappa molecules, respectively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1a7bccd69d0fd96347cf3d0b5130fc
https://pubmed.ncbi.nlm.nih.gov/2990608

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Cross-linking of membrane IgM on B CLL cells

Autor: Grillot-Courvalin C, Claire Hivroz, Jc, Brouet

Publikováno v: Europe PubMed Central

We report here the study of early events following surface Ig cross-linking such as Ca2+ mobilization and IP3 generation, in chronic lymphocytic leukemia (CLL) B cells. Those leukemic populations were previously shown to be frozen at different stages

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b16d40cf33b48d96ad52507eade894c4
https://pubmed.ncbi.nlm.nih.gov/3146745

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Acute leukemia with Burkitt's tumor cells: A study of six cases with special reference to lymphocyte surface markers

Autor: G Flandrin, JC Brouet, MT Daniel, JL Preud'homme

Publikováno v: Blood. 45(2)

In six patients with acute leukemia (about 2% of the patients referred for acute lymphoblastic leukemia) the blast cells invading bone marrow and blood showed all the cytologic, cytochemical, and electron microscopy features of Burkitt's tumor cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7e0f15e68bab56fa42f8695a9ab315
https://pubmed.ncbi.nlm.nih.gov/47248

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Anti-p53 antibodies are rarely detected in serum of patients with rheumatoid arthritis and Sjogren's syndrome

Autor: Mariette X, Jean Sibilia, Delaforge C, Bengoufa D, Jc, Brouet, Soussi T

Publikováno v: Scopus-Elsevier
Karolinska Institutet
Europe PubMed Central

To detect evidence of abnormalities of the p53 protein in autoimmune diseases. Mutation of the p53 protein may inhibit apoptosis and thereby lead to cancer and possibly play a role in the pathogenesis of autoimmune diseases.Serum antibodies to p53 ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a4897b947766243f8fb288dc0efc5565
http://www.scopus.com/inward/record.url?eid=2-s2.0-0032770624&partnerID=MN8TOARS

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