Zobrazeno 1 - 10
of 34
pro vyhledávání: '"JC Betts"'
Autor:
RJ Packer, N Shrine, R Hall, CA Melbourne, R Thompson, AT Williams, ML Paynton, AL Guyatt, PH Lee, C John, A Campbell, C Hayward, M de Vries, JM Vonk, J Davitte, E Hessel, D Michalovich, JC Betts, I Sayers, A Yeo, IP Hall, MD Tobin, LV Wain
BackgroundChronic sputum production impacts on quality of life and is a feature of many respiratory diseases. Identification of the genetic variants associated with chronic sputum production in a disease agnostic sample could improve understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0807dee241dc34e2c14db70ea93cc92b
https://doi.org/10.1101/2022.01.11.22269075
https://doi.org/10.1101/2022.01.11.22269075
Autor:
Carrasco-Zanini J; Human Genetics and Genomics, GSK Research and Development, Stevenage, UK. j.carrasco-zanini-sanchez@qmul.ac.uk.; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK. j.carrasco-zanini-sanchez@qmul.ac.uk.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK. j.carrasco-zanini-sanchez@qmul.ac.uk.; Computational Medicine, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany. j.carrasco-zanini-sanchez@qmul.ac.uk., Pietzner M; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK.; Computational Medicine, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany., Davitte J; Human Genetics and Genomics, GSK Research and Development, Collegeville, PA, USA., Surendran P; Human Genetics and Genomics, GSK Research and Development, Stevenage, UK., Croteau-Chonka DC; Human Genetics and Genomics, GSK Research and Development, Cambridge, MA, USA., Robins C; Human Genetics and Genomics, GSK Research and Development, Collegeville, PA, USA., Torralbo A; Institute of Health Informatics, University College London, London, UK., Tomlinson C; Institute of Health Informatics, University College London, London, UK.; National Institute for Health Research, Biomedical Research Centre, University College London Hospitals NHS Trust, London, UK., Grünschläger F; Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany.; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ) and DKFZ-ZMBH Alliance, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Fitzpatrick N; Institute of Health Informatics, University College London, London, UK., Ytsma C; Institute of Health Informatics, University College London, London, UK., Kanno T; Human Genetics and Genomics, GSK Research and Development, Collegeville, PA, USA., Gade S; Genomic Sciences, Cellzome GmbH, GSK Research and Development, Heidelberg, Germany., Freitag D; Human Genetics and Genomics, GSK Research and Development, Stevenage, UK., Ziebell F; Genomic Sciences, Cellzome GmbH, GSK Research and Development, Heidelberg, Germany., Haas S; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK.; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Charité-Universitätsmedizin, Berlin, Germany.; Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., Denaxas S; Institute of Health Informatics, University College London, London, UK.; National Institute for Health Research, Biomedical Research Centre, University College London Hospitals NHS Trust, London, UK.; Health Data Research UK, London, UK.; British Heart Foundation Data Science Centre, London, UK., Betts JC; Human Genetics and Genomics, GSK Research and Development, Stevenage, UK., Wareham NJ; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Hemingway H; Institute of Health Informatics, University College London, London, UK.; National Institute for Health Research, Biomedical Research Centre, University College London Hospitals NHS Trust, London, UK.; Health Data Research UK, London, UK., Scott RA; Human Genetics and Genomics, GSK Research and Development, Stevenage, UK. robert.a.scott@gsk.com., Langenberg C; MRC Epidemiology Unit, School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge, UK. claudia.langenberg@qmul.ac.uk.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK. claudia.langenberg@qmul.ac.uk.; Computational Medicine, Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany. claudia.langenberg@qmul.ac.uk.
Publikováno v:
Nature medicine [Nat Med] 2024 Sep; Vol. 30 (9), pp. 2489-2498. Date of Electronic Publication: 2024 Jul 22.
Autor:
Williams AT; Department of Population Health Sciences, University of Leicester, Leicester, UK., Shrine N; Department of Population Health Sciences, University of Leicester, Leicester, UK., Naghra-van Gijzel H; R&D, GSK, Stevenage, UK., Betts JC; R&D, GSK, Stevenage, UK., Chen J; Department of Population Health Sciences, University of Leicester, Leicester, UK., Hessel EM; R&D, GSK, Stevenage, UK., John C; Department of Population Health Sciences, University of Leicester, Leicester, UK., Packer R; Department of Population Health Sciences, University of Leicester, Leicester, UK., Reeve NF; Department of Population Health Sciences, University of Leicester, Leicester, UK., Yeo AJ; R&D, GSK, Stevenage, UK., Abner E; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Riia 23b, 51010, Estonia., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health, Norwegian University of Science and Technology, Levanger, Norway.; Department of Endocrinology, Clinic of Medicine, St Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Auvinen J; Medical Research Center Oulu, Oulu University Hospital, Center for Life Course Health Research, University of Oulu, Oulu, Finland., Bartz TM; Department of Biostatistics, University of Washington, Seattle, Washington, USA.; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA., Bradford Y; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health, Norwegian University of Science and Technology, Levanger, Norway.; Clinic of Thoracic and Occupational Medicine, St Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Chu S; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Crosslin DR; University of Washington, School of Medicine, Seattle, Washington, USA., Feng Q; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Riia 23b, 51010, Estonia., Gharib SA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.; Center for Lung Biology, Division of Pulmonary & Critical Care Medicine, Department of Medicine, University of Washington, Seattle, Washington, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Hebbring S; Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield, Wisconsin, USA., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health, Norwegian University of Science and Technology, Levanger, Norway., Järvelin MR; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.; Department of Epidemiology and Biostatistics, School of Public Health, MRC Centre for Environment and Health, Imperial College London, London, UK.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK., Jarvik GP; University of Washington, School of Medicine, Seattle, Washington, USA., Landis SH; R&D, GSK, Stockley Park, UK., Larson EB; University of Washington, School of Medicine, Seattle, Washington, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, Washington, USA., Liu J; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Luo Y; Department of Preventive Medicine, Northwestern University, Chicago, Illinois, USA., Moscati A; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Mullerova H; R&D, GSK, Stockley Park, UK., Namjou B; Center for Autoimmune Genomics and Etiology (CAGE), Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Quint JK; National Heart and Lung Institute, Imperial College London, London, UK., Ritchie MD; Department of Genetics and Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Sliz E; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Computational Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland., Stanaway IB; University of Washington, School of Medicine, Seattle, Washington, USA., Thomas L; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; BioCore - Bioinformatics Core Facility, Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Wilson JF; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Hall IP; Division of Respiratory Medicine and NIHR-Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Michalovich D; R&D, GSK, Stevenage, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Publikováno v:
Wellcome open research [Wellcome Open Res] 2023 Nov 21; Vol. 6, pp. 290. Date of Electronic Publication: 2023 Nov 21 (Print Publication: 2021).
Autor:
Packer RJ; Department of Population Health Sciences, University of Leicester, Leicester, UK richard.packer@leicester.ac.uk.; Leicester NIHR Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Shrine N; Department of Population Health Sciences, University of Leicester, Leicester, UK., Hall R; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Melbourne CA; Department of Population Health Sciences, University of Leicester, Leicester, UK., Thompson R; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Williams AT; Department of Population Health Sciences, University of Leicester, Leicester, UK., Paynton ML; Department of Population Health Sciences, University of Leicester, Leicester, UK., Guyatt AL; Department of Population Health Sciences, University of Leicester, Leicester, UK., Allen RJ; Department of Population Health Sciences, University of Leicester, Leicester, UK., Lee PH; Department of Population Health Sciences, University of Leicester, Leicester, UK., John C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK., de Vries M; University of Groningen, University Medical Center Groningen, Department of Epidemiology and Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands., Vonk JM; University of Groningen, University Medical Center Groningen, Department of Epidemiology and Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands., Davitte J; GSK R&D, Collegeville, PA, USA., Hessel E; GSK R&D, Stevenage, UK., Michalovich D; GSK R&D, Stevenage, UK., Betts JC; GSK R&D, Stevenage, UK., Sayers I; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Yeo A; GSK R&D, Stevenage, UK., Hall IP; Centre for Respiratory Research, NIHR Nottingham Biomedical Research Centre, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Publikováno v:
The European respiratory journal [Eur Respir J] 2023 Jun 15; Vol. 61 (6). Date of Electronic Publication: 2023 Jun 15 (Print Publication: 2023).
Autor:
Betts JC; R&D, GlaxoSmithKline Stevenage, United Kingdom., Mayer RJ; R&D, GlaxoSmithKline King of Prussia, Pennsylvania, USA., Tal-Singer R; R&D, GlaxoSmithKline King of Prussia, Pennsylvania, USA., Warnock L; R&D, GlaxoSmithKline Stevenage, United Kingdom., Clayton C; R&D, GlaxoSmithKline Stevenage, United Kingdom., Bates S; R&D, GlaxoSmithKline Stevenage, United Kingdom., Hoffman BE; R&D, GlaxoSmithKline King of Prussia, Pennsylvania, USA., Larminie C; R&D, GlaxoSmithKline Stevenage, United Kingdom., Singh D; University of Manchester, Medicines Evaluation Unit, University Hospital of South Manchester Foundations Trust Manchester, United Kingdom.
Publikováno v:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2015 Feb; Vol. 3 (1), pp. e00094. Date of Electronic Publication: 2014 Dec 09.
Autor:
Pheiffer C; MRC Centre for Molecular and Cellular Biology, Department of Medical Biochemistry, University of Stellenbosch Medical School, PO Box 19063, Tygerberg, 7505, South Africa., Betts JC; GlaxoSmithKline Research and Development, Stevenage, Hertfordshire SG1 2NY, UK., Flynn HR; GlaxoSmithKline Research and Development, Stevenage, Hertfordshire SG1 2NY, UK., Lukey PT; GlaxoSmithKline Research and Development, Stevenage, Hertfordshire SG1 2NY, UK., van Helden P; MRC Centre for Molecular and Cellular Biology, Department of Medical Biochemistry, University of Stellenbosch Medical School, PO Box 19063, Tygerberg, 7505, South Africa.
Publikováno v:
Microbiology (Reading, England) [Microbiology (Reading)] 2005 Apr; Vol. 151 (Pt 4), pp. 1139-1150.
Autor:
Cowley S; Department of Medicine, Division of Infectious Diseases, University of British Columbia, 2733 Heather St., Vancouver, British Columbia, Canada V5Z 3J5., Ko M, Pick N, Chow R, Downing KJ, Gordhan BG, Betts JC, Mizrahi V, Smith DA, Stokes RW, Av-Gay Y
Publikováno v:
Molecular microbiology [Mol Microbiol] 2004 Jun; Vol. 52 (6), pp. 1691-702.
Autor:
Downing KJ; MRC/NHLS/WITS Molecular Mycobacteriology Research Unit, School of Pathology of the University of the Witwatersrand and the National Health Laboratory Service, P.O. Box 1038, Johannesburg 2000, South Africa., Betts JC, Young DI, McAdam RA, Kelly F, Young M, Mizrahi V
Publikováno v:
Tuberculosis (Edinburgh, Scotland) [Tuberculosis (Edinb)] 2004; Vol. 84 (3-4), pp. 167-79.
Autor:
Kendall SL; Department of Pathology and Infectious Diseases, Royal Veterinary College, London NW1 0TU, UK., Movahedzadeh F, Rison SC, Wernisch L, Parish T, Duncan K, Betts JC, Stoker NG
Publikováno v:
Tuberculosis (Edinburgh, Scotland) [Tuberculosis (Edinb)] 2004; Vol. 84 (3-4), pp. 247-55.
Autor:
Betts JC; GlaxoSmithKline Research and Development, Stevenage, Hertfordshire, SG1 2NY, United Kingdom. joanna.c.betts@gsk.com, McLaren A, Lennon MG, Kelly FM, Lukey PT, Blakemore SJ, Duncan K
Publikováno v:
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2003 Sep; Vol. 47 (9), pp. 2903-13.