Genotoxicity investigation of araticum(Annona crassiflora Mart., 1841, Annonaceae) using SOS-Inductest and Ames test

Autor: JB. Vilar, PH. Ferri, L. Chen-Chen

Publikováno v: Brazilian Journal of Biology, Vol 71, Iss 1, Pp 197-202

Although the use of medicinal plants or natural products has increased in recent decades all over the world, little information is available on their potential risk to health. Annona crassiflora Mart., a plant commonly known as araticum in Brazil, ha

Externí odkaz: https://doaj.org/article/9e6ad582e00d4316b8b1c0244ad144f1

A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder.

Autor: Magrino J; Department of Biochemistry and Biotechnology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Munford V; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Martins DJ; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Homma TK; Genetic Endocrinology Unit, Cellular and Molecular Endocrinology Laboratory LIM25, Endocrinology Discipline of the Faculty of Medicine of the University of São Paulo, São Paulo, Brazil; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM42, Faculty of Medicine of the University of São Paulo, São Paulo, Brazil., Page B; Department of Biochemistry and Biotechnology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Gaubitz C; Department of Biochemistry and Biotechnology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Freire BL; Genetic Endocrinology Unit, Cellular and Molecular Endocrinology Laboratory LIM25, Endocrinology Discipline of the Faculty of Medicine of the University of São Paulo, São Paulo, Brazil; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM42, Faculty of Medicine of the University of São Paulo, São Paulo, Brazil., Lerario AM; Developmental Endocrinology Unit, Laboratory of Hormones and Molecular Genetics LIM42, Faculty of Medicine of the University of São Paulo, São Paulo, Brazil; Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor, Michigan, USA., Vilar JB; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Amorin A; Neurogenetics, Neurology Department, Faculty of Medicine of the University of São Paulo, São Paulo, Brazil., Leão EKE; Medical Genetics Service of the Professor Edgard Santos University Hospital - Federal University of Bahia, Salvador, Brazil., Kok F; Neurogenetics, Neurology Department, Faculty of Medicine of the University of São Paulo, São Paulo, Brazil; Mendelics Genomic Analysis, São Paulo, São Paulo, Brazil., Menck CF; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Jorge AA; Genetic Endocrinology Unit, Cellular and Molecular Endocrinology Laboratory LIM25, Endocrinology Discipline of the Faculty of Medicine of the University of São Paulo, São Paulo, Brazil., Kelch BA; Department of Biochemistry and Biotechnology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA. Electronic address: Brian.Kelch@umassmed.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 May; Vol. 299 (5), pp. 104656. Date of Electronic Publication: 2023 Mar 27.

Localization matters: nuclear-trapped Survivin sensitizes glioblastoma cells to temozolomide by elevating cellular senescence and impairing homologous recombination.

Autor: Reich TR; Department of Toxicology, University Medical Center, Mainz, Germany., Schwarzenbach C; Department of Toxicology, University Medical Center, Mainz, Germany., Vilar JB; Department of Toxicology, University Medical Center, Mainz, Germany., Unger S; Department of Toxicology, University Medical Center, Mainz, Germany., Mühlhäusler F; Department of Toxicology, University Medical Center, Mainz, Germany., Nikolova T; Department of Toxicology, University Medical Center, Mainz, Germany., Poplawski A; Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Mainz, Germany., Baymaz HI; Institute of Molecular Biology (IMB), Johannes Gutenberg University, Mainz, Germany., Beli P; Institute of Molecular Biology (IMB), Johannes Gutenberg University, Mainz, Germany., Christmann M; Department of Toxicology, University Medical Center, Mainz, Germany., Tomicic MT; Department of Toxicology, University Medical Center, Mainz, Germany. tomicic@uni-mainz.de.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Jul; Vol. 78 (14), pp. 5587-5604. Date of Electronic Publication: 2021 Jun 08.

A genetic cluster of patients with variant xeroderma pigmentosum with two different founder mutations.

Autor: Munford V; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Castro LP; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Souto R; Secretariat of Health, Goiania, GO, Brazil., Lerner LK; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Vilar JB; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Quayle C; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Asif H; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Schuch AP; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.; Department of Biochemistry and Molecular Biology, Federal University of Santa Maria, Santa Maria, RS, Brazil., de Souza TA; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Ienne S; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Alves FIA; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Moura LMS; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Galante PAF; Molecular Oncology Center, Hospital Sírio-Libanês, São Paulo, SP, Brazil., Camargo AA; Molecular Oncology Center, Hospital Sírio-Libanês, São Paulo, SP, Brazil., Liboredo R; Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Pena SDJ; Federal University of Minas Gerais, Belo Horizonte, MG, Brazil., Sarasin A; UMR 8200 CNRS, Institut Gustave Roussy and University Paris-Saclay, Villejuif, France., Chaibub SC; General Hospital of Goiania, Goiania, GO, Brazil., Menck CFM; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.

Publikováno v: The British journal of dermatology [Br J Dermatol] 2017 May; Vol. 176 (5), pp. 1270-1278. Date of Electronic Publication: 2017 Mar 22.

Antimutagenicity protection of Ginkgo biloba extract (Egb 761) against mitomycin C and cyclophosphamide in mouse bone marrow.

Autor: Vilar JB; Departamento de Biologia Geral, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, GO, Brazil., Leite KR, Chen Chen L

Publikováno v: Genetics and molecular research : GMR [Genet Mol Res] 2009 Mar 24; Vol. 8 (1), pp. 328-33. Date of Electronic Publication: 2009 Mar 24.