Zobrazeno 1 - 10
of 352
pro vyhledávání: '"JB Weinberg"'
Autor:
Joseph O. Moore, Russell P. Hall, Takashi Matsushita, Mayuka Horikawa, Ayumi Yoshizaki, Louis F. Diehl, Daphne R. Friedman, Guglielmo M. Venturi, Karen M. Matta, David J. DiLillo, J M Bryant, Yohei Iwata, Thomas F. Tedder, JB Weinberg, Giandomenico Russo, Youwei Chen, Alicia D. Volkheimer, Jon P. Gockerman, Mark C. Lanasa
Publikováno v:
Leukemia. 27:170-182
Chronic lymphocytic leukemia (CLL) can be immunosuppressive in humans and mice, and CLL cells share multiple phenotypic markers with regulatory B cells that are competent to produce interleukin (IL)-10 (B10 cells). To identify functional links betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024f4439b0af091d83988036895fce1d
https://doi.org/10.1038/leu.2012.165
https://doi.org/10.1038/leu.2012.165
Autor:
George J. Cianciolo, Karen M. Bond, Daphne R. Friedman, Mark C. Lanasa, Louis F. Diehl, M N Kennedy, Salvatore V. Pizzo, Joseph O. Moore, JB Weinberg, Yvonne M. Mowery, Jon P. Gockerman
Publikováno v:
Leukemia. 24:1580-1587
B-cell chronic lymphocytic leukemia (CLL) is characterized by slow accumulation of malignant cells, which are supported in the microenvironment by cell-cell interactions and soluble cytokines such as tumor necrosis factor (TNF). We evaluated the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4b94f654aecc02a0047bca85a32e0a
https://doi.org/10.1038/leu.2010.150
https://doi.org/10.1038/leu.2010.150
Autor:
Jon P. Gockerman, Joseph O. Moore, Mirta Mihovilovic, Karen M. Bond, Louis F. Diehl, Marc C. Levesque, JB Weinberg, Alicia D. Volkheimer, Youwei Chen, David A. Rizzieri, Robert M. DeKroon, Ning Jiang, Warren J. Strittmatter, C. M. De Castro
Publikováno v:
Leukemia. 22:2184-2192
Survival of chronic lymphocytic leukemia (CLL) cells requires sustained activation of the antiapoptotic PI-3-K/Akt pathway, and many therapies for CLL cause leukemia cell death by triggering apoptosis. Blood lipoprotein particles are either pro- or a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c475755b3b95f88ba2c0c79d5dc4a19c
https://doi.org/10.1038/leu.2008.241
https://doi.org/10.1038/leu.2008.241
Autor:
Marc C. Levesque, JB Weinberg
Publikováno v:
Current Molecular Medicine. 4:777-786
Atherosclerosis is an inflammatory disorder, and the inflammation associated with systemic lupus erythematosus (SLE) accelerates the development of atherosclerosis. Nitric oxide (NO) is an important mediator of inflammation including the inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96bdfb312f356ab06672f17e4d9f8646
https://doi.org/10.2174/1566524043359872
https://doi.org/10.2174/1566524043359872
Autor:
D L Wilson, Youwei Chen, Bethany E. Beasley, R Silber, Charles W. O’Loughlin, Mary A. Misukonis, David J. Adams, JB Weinberg, Marc C. Levesque
Publikováno v:
Leukemia. 17:442-450
Chronic lymphocytic leukemia (B-CLL) is characterized by the accumulation of long-lived non-dividing CD5(+) B cells. Nitric oxide (NO) is an important regulator of apoptosis, and the viability of cultured B-CLL cells may be dependent on the autocrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077d006c641c45313aea59ef1e719ac6
https://doi.org/10.1038/sj.leu.2402783
https://doi.org/10.1038/sj.leu.2402783
Publikováno v:
Leukemia. 12:1461-1466
Nitric oxide (NO) has potent antiproliferative properties. In previous work we have shown that NO inhibits growth, induces differentiation and modulates gene expression in acute nonlymphocytic leukemia (ANLL) cells. The goal of this work was to deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9d3619825af1e82c43801b743539c6
https://doi.org/10.1038/sj.leu.2401131
https://doi.org/10.1038/sj.leu.2401131
Publikováno v:
Blood. 88:1857-1864
Nitric oxide (NO) is a paramagnetic gas that has been implicated in a wide range of biologic functions. The common pathway to evoke the functional response frequently involves the formation of an iron- nitrosyl complex in a target (heme) protein. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bcdb624cd0659fcc858baadcd03627d
https://doi.org/10.1182/blood.v88.5.1857.1857
https://doi.org/10.1182/blood.v88.5.1857.1857
Autor:
Paul J. Shami, JB Weinberg
Publikováno v:
Blood. 87:977-982
Nitric oxide (NO) is a reactive molecule with numerous physiologic and pathophysiologic roles affecting the nervous, cardiovascular, and immune systems. In previous work, we have demonstrated that NO inhibits the growth and induces the monocytic diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f981353faced4f6c4b3f856f9e47b0b
https://doi.org/10.1182/blood.v87.3.977.bloodjournal873977
https://doi.org/10.1182/blood.v87.3.977.bloodjournal873977
Publikováno v:
Blood. 86:1281-1287
Various cobalamins act as important enzyme cofactors and modulate cellular function. We investigated cobalamins for their abilities to modify productive human immunodeficiency virus-1 (HIV-1) infection of hematopoietic cells in vitro. We show that hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f402e91ab8cc8c3b91422e712ab0e80d
https://doi.org/10.1182/blood.v86.4.1281.bloodjournal8641281
https://doi.org/10.1182/blood.v86.4.1281.bloodjournal8641281
Autor:
B McDonald, Derrick L. Sauls, KE Bachus, PJ Shami, JB Weinberg, WA Dittman, ER Wood, Mary A. Misukonis, SN Mason, GK Smith
Publikováno v:
Blood. 86:1184-1195
Nitric oxide (NO) is produced by numerous different cell types, and it is an important regulator and mediator of many processes including smooth muscle relaxation, neurotransmission, and murine macrophage- mediated cytotoxicity for microbes and tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560f12072e2e8c7130cf2cebe69af2ed
https://doi.org/10.1182/blood.v86.3.1184.1184
https://doi.org/10.1182/blood.v86.3.1184.1184