NMR Reveals an Undeclared Constituent in Custom Synthetic Peptides

Autor: Mary P. Choules, JB McAlpine, Charlotte Simmler, Matthias Niemitz, Anton Bzhelyansky, Jonathan Bisson, Guido F. Pauli, Gabriel I. Giancaspro

Publikováno v: J Pharm Biomed Anal
Journal of Pharmaceutical and Biomedical Analysis
Journal of Pharmaceutical and Biomedical Analysis, Elsevier, 2020, 178, pp.112915. ⟨10.1016/j.jpba.2019.112915⟩
Journal of Pharmaceutical and Biomedical Analysis, 2020, 178, pp.112915. ⟨10.1016/j.jpba.2019.112915⟩

Whereas generic, LC-based pharmaceutical control quality procedures depend largely on the detection mode and can be particularly ‘blind’ to certain impurities, NMR is a more versatile and, thus, often more judicious detector. While adulteration p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4f5df7fd07c1f2967cf9d82986bfcd
https://europepmc.org/articles/PMC6913887/

Minimizing the problems with 'PIMPs'

Autor: JB McAlpine, Jonathan Bisson, Guido F. Pauli

Publikováno v: Planta Medica. 81

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f552203f550168df31b7a52269a242e5
https://doi.org/10.1055/s-0035-1556293

The generally useful estimate of solvent systems method enables the rapid separation of curcuminoids by countercurrent separation

Autor: Yong Liu, S-N Chen, Guido F. Pauli, JB Friesen, JB McAlpine

Publikováno v: Planta Medica. 81

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ccad447bda0d2fae59940d91c3c7342
https://doi.org/10.1055/s-0035-1556274

TLC-bioautography linked with guess: A truely targeted active compound isolation process

Autor: Guido F. Pauli, S-N Chen, Edyta M. Grzelak, JB Friesen, JB McAlpine, J Cheng, Yong Liu, Joo Won Suh, DC Lankin, Joo Won Nam, Birgit U. Jaki, SH Cho, SH Yang, H Lee, Scott G. Franzblau, Jy Kim

Publikováno v: Planta Medica. 81

In order to optimize the isolation procedure of anti-TB lead compounds, a truly targeted isolation approach was developed, which aligns (HP)TLC-bioautography with GUESS1 based countercurrent separation (CCS). (HP)TLC-bioautography was specifically de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d32f8cec608927f82f28780562f1c7b
https://doi.org/10.1055/s-0035-1556275

Dissemination of original NMR data enhances the reproducibility of natural product research

Autor: S-N Chen, Matthias Niemitz, DC Lankin, Dean J. Tantillo, Jonathan Bisson, JT Shaw, JB Friesen, JB McAlpine, Guido F. Pauli, Cristian Soldi

Publikováno v: Planta Medica. 81

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cee9b1074d82b1fa6acc0eebae3cf6bf
https://doi.org/10.1055/s-0035-1556552