Výsledky vyhledávání - "JB Lecaillon"

Pharmacokinetics of CGP 6140 (amocarzine) after oral administration of single 100-1600 mg doses to patients with onchocerciasis

Autor: A.A. Poltera, CD Ginger, JB Lecaillon, JP Dubois, K Awadzi

Publikováno v: British Journal of Clinical Pharmacology. 30:625-628

The concentrations of CGP 6140 [4-nitro-4'-(N-methyl-piperazinylthiocarbonylamido)-diphenylamine] and of its N-oxide metabolite, CGP 13,231, were measured in plasma and urine after single oral dose of 100-1600 mg of CGP 6140 to 41 fasted Ghanaian pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6532138d758d6e29404832bf6a89b7e
https://doi.org/10.1111/j.1365-2125.1990.tb03824.x

Zobrazit plný text záznamu

Pharmacokinetics of cadralazine and its hydrazino-metabolite in patients with renal impairment after repeated administration of 5 mg once daily

Autor: J. Ménard, Patrick Brunel, Marichal Jf, JB Lecaillon, P. Brignon, B. Faller, Godbillon J

Publikováno v: European journal of drug metabolism and pharmacokinetics. 17(3)

Since the hydrazino-pyridazine metabolite of cadralazine, CGP 22 639 is believed to contribute to the activity of the drug, its pharmacokinetics and that of cadralazine were investigated in 8 hypertensive patients with renal impairment. The creatinin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a48b08bdd873214a754a6e7c9320d2
https://pubmed.ncbi.nlm.nih.gov/1490491

Zobrazit plný text záznamu

[Distomatosis of the bile ducts. Value of retrograde cholangiography. Efficacy of triclabendazole]

Autor: De Ronde T, Mélange M, Bernard Van Beers, Jp, Trigaux, Dive C, Jb, Lecaillon, Aa, Poltera

Publikováno v: Europe PubMed Central

A case of chronic biliary fascioliasis is reported, which was confirmed by endoscopic retrograde cholangiography. After unsuccessful attempts of treatment with classic antiparasitic drugs, cure was obtained with triclabendazole the absorption of whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c79fd06a541cf923d9ed24a5d3c2ee17
https://pubmed.ncbi.nlm.nih.gov/1332351

Zobrazit plný text záznamu

The influence of food on the pharmacokinetics of CGP 6140 (amocarzine) after oral administration of a 1200 mg single dose to patients with onchocerciasis

Autor: JP Dubois, E Pichard, G Soula, A.A. Poltera, JB Lecaillon, CD Ginger

Eleven male patients from Mali with Onchocerca volvulus infections received in random order a 1200 mg single oral dose of CGP 6140 after an overnight fast and after food intake. The concentrations of CGP 6140 and of its N-oxide metabolite, CGP 13231,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e807e91a4271bbdf4e8af6f9146caf2
https://europepmc.org/articles/PMC1368257/

Zobrazit plný text záznamu

Influence of acetylator status on the haemodynamic effects and pharmacokinetics of cadralazine in healthy subjects

Autor: Joël Ménard, P Imhof, JB Lecaillon, T. T. Guyene, Patrick Brunel

Publikováno v: British journal of clinical pharmacology. 29(5)

1. Cadralazine is a new antihypertensive agent which causes peripheral vasodilation, probably mediated by a hydrazinopyridazine metabolite. 2. The possible influence of acetylator status on the pharmacokinetics and haemodynamics of the drug was studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e799b78e4a8f87ce9cf12a3aee14d64d
https://pubmed.ncbi.nlm.nih.gov/2190629

Zobrazit plný text záznamu

Influence of food on the absorption of metoprolol administered as an Oros drug delivery system to man

Autor: P Massias, F Abadie, JP Schoeller, JB Lecaillon

Publikováno v: British Journal of Clinical Pharmacology. 19:245S-249S

The influence of food on the release, absorption and metabolism of metoprolol has been studied after single administration of a 19/190 Oros system to eight healthy volunteers on four occasions, once after an overnight fast, and just before each of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b951014b07b566ab5fafe145816822
https://doi.org/10.1111/j.1365-2125.1985.tb02770.x

Zobrazit plný text záznamu

Akademický článek

Pharmacokinetics and tolerability of formoterol in healthy volunteers after a single high dose of Foradil dry powder inhalation via Aerolizer.

Autor: Lecaillon JB; Novartis Pharma, Rueil-Malmaison, France., Kaiser G, Palmisano M, Morgan J, Della Cioppa G

Publikováno v: European journal of clinical pharmacology [Eur J Clin Pharmacol] 1999 Apr; Vol. 55 (2), pp. 131-8.

Zobrazit plný text záznamu

Akademický článek

Effect of food on the bioavailability of triclabendazole in patients with fascioliasis.

Autor: Lecaillon JB; Novartis Pharma S.A., Drug Metabolism & Pharmacokinetics, Rueil-Malmaison, France., Godbillon J, Campestrini J, Naquira C, Miranda L, Pacheco R, Mull R, Poltera AA

Publikováno v: British journal of clinical pharmacology [Br J Clin Pharmacol] 1998 Jun; Vol. 45 (6), pp. 601-4.

Zobrazit plný text záznamu

Akademický článek

The influence of food on the disposition of the antiepileptic rufinamide in healthy volunteers.

Autor: Cardot JM; Laboratoires Ciba-Geigy, Bioanalytics and Pharmacokinetics (BPK), Rueil-Malmaison, France., Lecaillon JB, Czendlik C, Godbillon J

Publikováno v: Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 1998 May; Vol. 19 (4), pp. 259-62.

Zobrazit plný text záznamu

Akademický článek

Automated and sensitive method for the determination of formoterol in human plasma by high-performance liquid chromatography and electrochemical detection.

Autor: Campestrini J; Novartis Pharma, Drug Metabolism and Pharmacokinetics, Rueil-Malmaison, France., Lecaillon JB, Godbillon J

Publikováno v: Journal of chromatography. B, Biomedical sciences and applications [J Chromatogr B Biomed Sci Appl] 1997 Dec 19; Vol. 704 (1-2), pp. 221-9.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání