Optimisation of DNA extraction from the crustacean Daphnia

Autor: Camila Gonçalves Athanasio, James K. Chipman, Mark R. Viant, Leda Mirbahai

Publikováno v: PeerJ, Vol 4, p e2004 (2016)

Daphnia are key model organisms for mechanistic studies of phenotypic plasticity, adaptation and microevolution, which have led to an increasing demand for genomics resources. A key step in any genomics analysis, such as high-throughput sequencing, i

Externí odkaz: https://doaj.org/article/d5ec689de1744095b1f89b85e1fff7cc

Gene expression and metabolic responses of HepG2/C3A cells exposed to flame retardants and dust extracts at concentrations relevant to indoor environmental exposures

Autor: Mohamed Abou-Elwafa Abdallah, Tim D. Williams, Mark R. Viant, James K. Chipman, Stuart Harrad, Jinkang Zhang

Publikováno v: Chemosphere. 144:1996-2003

Humans are routinely exposed to mixtures of flame retardants (FRs) from multiple sources including indoor dust. As a model to explore the potential effects of FR exposure from indoor dust on human health, the molecular responses of human hepatoma cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd07eb6bfa326e221875bd1c213c7913
https://doi.org/10.1016/j.chemosphere.2015.10.014

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish

Autor: Alexandra Rolaki, Marlies Halder, Nancy D. Denslow, Dick Roelofs, Raquel N. Carvalho, Ksenia J. Groh, Cheryl A. Murphy, Kristin Schirmer, Karen H. Watanabe, James K. Chipman

Publikováno v: Chemosphere, 120
Chemosphere, 120, 778-792. Elsevier Limited
Groh, K J, Carvalho, R N, Chipman, J K, Denslow, N D, Halder, M, Murphy, C A, Roelofs, D, Rolaki, A, Schirmer, K & Watanabe, K H 2015, ' Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish ', Chemosphere, vol. 120, pp. 778-792 . https://doi.org/10.1016/j.chemosphere.2014.10.006

Adverse outcome pathways (AOPs) organize knowledge on the progression of toxicity through levels of biological organization. By determining the linkages between toxicity events at different levels, AOPs lay the foundation for mechanism-based alternat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adcf07ac00d153925a0cc12dbe0eb2b

Development of haemostatic decontaminants for the treatment of wounds contaminated with chemical warfare agents. 1: Evaluation ofin vitroclotting efficacy in the presence of certain contaminants

Autor: John S. Graham, Helen L. Lydon, Robert P. Chilcott, James K. Chipman, Christopher H. Dalton, Charlotte A. Hall

Publikováno v: Journal of Applied Toxicology. 35:536-542

The treatment of penetrating, haemorrhaging injuries sustained within a hazardous environment may be complicated by contamination with toxic chemicals. There are currently no specific medical countermeasures for such injuries. Haemostats with an abso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::36efd9a8cf5973c98e9ad79f7e111f7b
https://doi.org/10.1002/jat.3019

Protein Corona Modulates Uptake and Toxicity of Nanoceria via Clathrin-Mediated Endocytosis

Autor: Emily J. Guggenheim, Robert K. Shaw, Abdullah O. Khan, Hsueh-Shih Chen, Mark R. Viant, James K. Chipman, Joshua Z. Rappoport, Julie Mazzolini, Ralf J. M. Weber

Publikováno v: The Biological bulletin. 231(1)

Particles present in diesel exhaust have been proposed as a significant contributor to the development of acute and chronic lung diseases, including respiratory infection and allergic asthma. Nanoceria (CeO2 nanoparticles) are used to increase fuel e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0757f9e58fdd0fd19bb0fcf3b440af
https://pubmed.ncbi.nlm.nih.gov/27638694