Zobrazeno 1 - 10
of 78
pro vyhledávání: '"JAMES J. STARLING"'
Autor:
Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell
p38α mitogen-activated protein kinase (MAPK) is activated in cancer cells in response to environmental factors, oncogenic stress, radiation, and chemotherapy. p38α MAPK phosphorylates a number of substrates, including MAPKAP-K2 (MK2), and regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22628225105d10e01b1823421dc49781
https://doi.org/10.1158/1535-7163.c.6536578.v1
https://doi.org/10.1158/1535-7163.c.6536578.v1
Autor:
Anne H. Dantzig, Everett J. Perkins, Enaksha R. Wickremsinhe, James J. Starling, Gregory P. Donoho, Robert L. Shepard, Sara Durland–Busbice, Susan E. Pratt
PDF file - 112K, Supplementary Figure 2 - in vivo study body weights
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b26de16f0ee5d751321264d9d15621d
https://doi.org/10.1158/1535-7163.22498848
https://doi.org/10.1158/1535-7163.22498848
Autor:
Anne H. Dantzig, Everett J. Perkins, Enaksha R. Wickremsinhe, James J. Starling, Gregory P. Donoho, Robert L. Shepard, Sara Durland–Busbice, Susan E. Pratt
PDF file - 316K, Supplementary Figure 1 - in vivo study body weights
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b531576d023873277f8bbc6e15fa91
https://doi.org/10.1158/1535-7163.22498851
https://doi.org/10.1158/1535-7163.22498851
Autor:
Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell
PDF file - 43K, Effect of LY2228820 on MK2 phosphorylation in mouse peripheral blood mononuclear cells (PBMC) and from patients with multiple myeloma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22324d5e3fb3ac4e9a4d4c1e89f1bae3
https://doi.org/10.1158/1535-7163.22500817.v1
https://doi.org/10.1158/1535-7163.22500817.v1
Autor:
Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell
PDF file - 86K, Supplemental Table 1. Kinases where LY2228820 shows >1000-fold selectivity in vitro (p38 MAPK vs. other kinase).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32264138e74601170f5f533f626867e
https://doi.org/10.1158/1535-7163.22500811.v1
https://doi.org/10.1158/1535-7163.22500811.v1
Autor:
Jian Du, Alfonso de Dios, Richard B. Gaynor, James J. Starling, Xiang S. Ye, Amit Aggarwal, Song Wu, Shuyu Li, Yuewei Qian, Gregory P. Donoho, Aimee B. Lin, Bart W. Halstead, Sean E. Sissons, Douglas Zeckner, Robert T. Foreman, Timothy I. Meier, Phillip W. Iversen, Damien M. Cronier, Rose T. Ajamie, Graham N. Wishart, Raquel Torrres, Santiago Carballares, Kevin R. Fales, Emiko L. Kreklau, Maria J. Lallena, Tinggui Yin
PDF - 1128K, Figure S1. Knockdown of CDK7 and CDK9 can inhibit RNAP II CTD P-Ser2 and P-Ser5. Figure S2. LY2857785 and flavopiridol inhibit MCL-1, XIAP protein expression and induce CASP-3 and cleaved PARP in AML cell MV-4-11. Table S1. LY2857785 inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb62eb48bfbf19159c380c73cb9da0d
https://doi.org/10.1158/1535-7163.22500105.v1
https://doi.org/10.1158/1535-7163.22500105.v1
Autor:
Anne H. Dantzig, Everett J. Perkins, Enaksha R. Wickremsinhe, James J. Starling, Gregory P. Donoho, Robert L. Shepard, Sara Durland–Busbice, Susan E. Pratt
PDF file - 72K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b0837c46c6fb9854d5f51893366d9a
https://doi.org/10.1158/1535-7163.22498845.v1
https://doi.org/10.1158/1535-7163.22498845.v1
Autor:
Sheng-Bin Peng, Richard P. Beckmann, James J. Starling, Edward M. Chan, Sean G. Buchanan, Youyan Zhang, Robert D. Van Horn, Lysiane Huber, Teresa F. Burke, Vipin Yadav
Supplementary figure S1 describes the molecular mechanisms of resistance across vemurafenib-resistant cell line models. Supplementary figure S2 serves as a repeat of figure 3a describing development of in vivo model of resistance, and demonstrates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bd36236a130dcd815e4329a2a4012f
https://doi.org/10.1158/1535-7163.22501512.v1
https://doi.org/10.1158/1535-7163.22501512.v1
Autor:
Xiang S. Ye, Yong Wang, Juan A. Velasco, Courtney Tate, James J. Starling, Louis F. Stancato, Chuan Shih, Susan E. Pratt, Stephen H. Parsons, Songqing Na, Denis McCann, Mary Mader, Enrique Jambrina, Jeremy R. Graff, Raymond Gilmour, Alfonso De Dios, Edward M. Chan, Harold B. Brooks, Nathan A. Brooks, Bryan D. Anderson, Robert M. Campbell
PDF file - 90K, shRNA silencing of p38a MAPK in U-87MG glioma (Westerns and xenograft tumor growth data).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d956222196f28eb3db5494e81e7cc02
https://doi.org/10.1158/1535-7163.22500814.v1
https://doi.org/10.1158/1535-7163.22500814.v1
Autor:
Jian Du, Alfonso de Dios, Richard B. Gaynor, James J. Starling, Xiang S. Ye, Amit Aggarwal, Song Wu, Shuyu Li, Yuewei Qian, Gregory P. Donoho, Aimee B. Lin, Bart W. Halstead, Sean E. Sissons, Douglas Zeckner, Robert T. Foreman, Timothy I. Meier, Phillip W. Iversen, Damien M. Cronier, Rose T. Ajamie, Graham N. Wishart, Raquel Torrres, Santiago Carballares, Kevin R. Fales, Emiko L. Kreklau, Maria J. Lallena, Tinggui Yin
XLSX - 54K, Table S2. 261 probsets gene signature in sens and res cell lines in Excel format.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70fa29c964bb208bbfee904a5d0548e
https://doi.org/10.1158/1535-7163.22500102
https://doi.org/10.1158/1535-7163.22500102