Zobrazeno 1 - 10
of 268
pro vyhledávání: '"JAMES D. OTVOS"'
Autor:
Sant Kumar, Katherine M. Conners, Joseph J. Shearer, Jungnam Joo, Sarah Turecamo, Maureen Sampson, Anna Wolska, Alan T. Remaley, Margery A. Connelly, James D. Otvos, Nicholas B. Larson, Suzette J. Bielinski, Véronique L. Roger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)
Background Frailty is common in heart failure (HF) and is associated with death but not routinely captured clinically. Frailty is linked with inflammation and malnutrition, which can be assessed by a novel plasma multimarker score: the metabolic vuln
Externí odkaz:
https://doaj.org/article/a7804c95517543f4979d503539466b34
Autor:
Rebecca O. Oyetoro, Katherine M. Conners, Jungnam Joo, Sarah Turecamo, Maureen Sampson, Anna Wolska, Alan T. Remaley, James D. Otvos, Margery A. Connelly, Nicholas B. Larson, Suzette J. Bielinski, Maryam Hashemian, Joseph J. Shearer, Véronique L. Roger
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundThe relationship between ketone bodies (KB) and mortality in patients with heart failure (HF) syndrome has not been well established.ObjectivesThe aim of this study is to assess the distribution of KB in HF, identify clinical correlates, an
Externí odkaz:
https://doaj.org/article/b66c5f7e55c94c8fa65bd28c91799bee
Autor:
Austin Deets, Parag H. Joshi, Alvin Chandra, Kavisha Singh, Amit Khera, Salim S. Virani, Christie M. Ballantyne, James D. Otvos, Robin P. F. Dullaart, Eke G. Gruppen, Margery A. Connelly, Colby Ayers, Ann Marie Navar, Ambarish Pandey, John T. Wilkins, Anand Rohatgi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background High‐density lipoprotein (HDL) particle concentration likely outperforms HDL cholesterol in predicting atherosclerotic cardiovascular events. Whether size‐based HDL subspecies explain the atheroprotective associations of HDL particle c
Externí odkaz:
https://doaj.org/article/3ef89734bb2f46c88e6ec6de3a77d86f
Autor:
Erwin Garcia, Irina Shalaurova, Steven P. Matyus, Lita A. Freeman, Edward B. Neufeld, Maureen L. Sampson, Rafael Zubirán, Anna Wolska, Alan T. Remaley, James D. Otvos, Margery A. Connelly
Publikováno v:
Molecules, Vol 29, Iss 3, p 564 (2024)
Lipoprotein X (LP-X) is an abnormal cholesterol-rich lipoprotein particle that accumulates in patients with cholestatic liver disease and familial lecithin–cholesterol acyltransferase deficiency (FLD). Because there are no high-throughput diagnosti
Externí odkaz:
https://doaj.org/article/7b4075c84b5d4606bf457aaea0b6e7e5
Autor:
Konrad T. Sawicki, Hongyan Ning, Norrina B. Allen, Mercedes R. Carnethon, Amisha Wallia, James D. Otvos, Issam Ben-Sahra, Elizabeth M. McNally, Janet K. Snell-Bergeon, John T. Wilkins
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
BACKGROUND Elevated circulating branched chain amino acids (BCAAs), measured at a single time point in middle life, are strongly associated with an increased risk of developing type 2 diabetes mellitus (DM). However, the longitudinal patterns of chan
Externí odkaz:
https://doaj.org/article/779ab5635c88401293a683894932f4f4
Autor:
Maureen Sampson, Rami A. Ballout, Daniel Soffer, Anna Wolska, Sierra Wilson, Jeff Meeusen, Leslie J. Donato, Erica Fatica, James D. Otvos, Eliot A. Brinton, Robert S. Rosenson, Peter Wilson, Marcelo Amar, Robert Shamburek, Sotirios K. Karathanasis, Alan T. Remaley
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-21 (2021)
Highlights A new algorithm is described for categorizing dyslipidemic patients into Fredrickson-like lipoprotein phenotypes except for Type III. The new lipoprotein phenotypes were validated by NMR-lipoprotein analysis and by agarose gel electrophore
Externí odkaz:
https://doaj.org/article/00d7e07ea77947e29c74d7d4034f28c2
Autor:
Kayla A. Riggs, Parag H. Joshi, Amit Khera, James D. Otvos, Philip Greenland, Colby R. Ayers, Anand Rohatgi
Publikováno v:
American Journal of Preventive Cardiology, Vol 12, Iss , Pp 100373- (2022)
Objective: Inflammatory markers are associated with cardiovascular disease (CVD); however, the ability to specifically predict myocardial infarction (MI) as well as ischemic stroke remains unknown. There has not been a direct comparison of the associ
Externí odkaz:
https://doaj.org/article/9fd6e59b8af54cdfa6b9a504de78a8db
Autor:
Virginia Byers Kraus, Sisi Ma, Roshan Tourani, Gerda G. Fillenbaum, Bruce M. Burchett, Daniel C. Parker, William E. Kraus, Margery A. Connelly, James D. Otvos, Harvey Jay Cohen, Melissa C. Orenduff, Carl F. Pieper, Xin Zhang, Constantin F. Aliferis
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104292- (2022)
Summary: Background: The hard endpoint of death is one of the most significant outcomes in both clinical practice and research settings. Our goal was to discover direct causes of longevity from medically accessible data. Methods: Using a framework th
Externí odkaz:
https://doaj.org/article/03e3db4d345a43a484bb3be87612d634
Autor:
Michele Mietus-Snyder, William Suslovic, Meghan Delaney, Martin P. Playford, Rami A. Ballout, John R. Barber, James D. Otvos, Roberta L. DeBiasi, Nehal N. Mehta, Alan T. Remaley
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundMyriad roles for high-density lipoprotein (HDL) beyond atheroprotection include immunologic functions implicated in the severity of coronavirus disease-2019 (COVID-19) in adults. We explored whether there is an association between HDL and C
Externí odkaz:
https://doaj.org/article/7e5f7ab623b341c6bbba59110c3d23fc
Autor:
Erwin Garcia, Dennis W. Bennett, Margery A. Connelly, Elias J. Jeyarajah, Franklin C. Warf, Irina Shalaurova, Steven P. Matyus, Justyna Wolak-Dinsmore, David N. Oskardmay, Randolph M. Young, Maureen Sampson, Alan T. Remaley, James D. Otvos
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-11 (2020)
Abstract Background Standard lipid panel assays employing chemical/enzymatic methods measure total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C), from which are calculated estimates of low-density lipoprotein
Externí odkaz:
https://doaj.org/article/3c2856fe12cf477db880001f9fbcec69