Zobrazeno 1 - 10
of 224
pro vyhledávání: '"JAMES D. McCHESNEY"'
Autor:
Pius S. Fasinu, Narayan D. Chaurasiya, N. P. Dhammika Nanayakkara, Yan‑Hong Wang, H. M. T. Bandara Herath, Bharathi Avula, James D. McChesney, David Jollow, Larry A. Walker, Babu L. Tekwani
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Primaquine (PQ) has been used for the radical cure of relapsing Plasmodium vivax malaria for more than 60 years. PQ is also recommended for prophylaxis and prevention of transmission of Plasmodium falciparum. However, clinical uti
Externí odkaz:
https://doaj.org/article/0b7d431ad13d471f97a9489095c3c336
Autor:
Washim Khan, Yan-Hong Wang, Narayan D. Chaurasiya, N. P. Dhammika Nanayakkara, H. M. Bandara Herath, Kerri A. Harrison, Gray Dale, Donald A. Stanford, Eric P. Dahl, James D. McChesney, Waseem Gul, Mahmoud A. ElSohly, David Jollow, Babu L. Tekwani, Larry A. Walker
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Primaquine (PQ) is an 8-aminoquinoline antimalarial, active against dormant Plasmodium vivax hypnozoites and P. falciparum mature gametocytes. PQ is currently used for P. vivax radical cure and prevention of malaria transmission. PQ is a racemic drug
Externí odkaz:
https://doaj.org/article/801eb27d382a49469704097ef32cf698
Autor:
Pius S. Fasinu, N. P. Dhammika Nanayakkara, Yan-Hong Wang, Narayan D. Chaurasiya, H. M. Bandara Herath, James D. McChesney, Bharathi Avula, Ikhlas Khan, Babu L. Tekwani, Larry A. Walker
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-8 (2019)
Abstract Background The activity and haemolytic toxicity associated with primaquine has been linked to its reactive metabolites. The reactive metabolites are thought to be primarily formed through the action of cytochrome P450-mediated pathways. Huma
Externí odkaz:
https://doaj.org/article/bef9c2cb44b441a495645be8bf521194
Autor:
Bharathi Avula, Babu L. Tekwani, Narayan D. Chaurasiya, Pius Fasinu, N. P. Dhammika Nanayakkara, H. M. T. Bhandara Herath, Yan-Hong Wang, Ji-Yeong Bae, Shabana I. Khan, Mahmoud A. Elsohly, James D. McChesney, Peter A. Zimmerman, Ikhlas A. Khan, Larry A. Walker
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-14 (2018)
Abstract Background Primaquine (PQ), an 8-aminoquinoline, is the only drug approved by the United States Food and Drug Administration for radical cure and prevention of relapse in Plasmodium vivax infections. Knowledge of the metabolism of PQ is crit
Externí odkaz:
https://doaj.org/article/654e746afd904edc9c8c9089d7d34a5d
Autor:
Wilmer H. Perera, James D. McChesney
Publikováno v:
Molecules, Vol 26, Iss 7, p 1915 (2021)
Stevia rebaudiana (Bertoni) Bertoni is a plant species native to Brazil and Paraguay well-known by the sweet taste of their leaves. Since the recognition of rebaudioside A and other steviol glycosides as generally recognized as safe by the United Sta
Externí odkaz:
https://doaj.org/article/c2747cdf07ba4ef5bee544ac5f74dc95
Autor:
Renata F. J. Tiossi, Juliana C. Da Costa, Mariza A. Miranda, Fabíola S. G. Praça, Maria Vitória L. B. Bentley, Jairo K. Bastos, James D. McChesney
Publikováno v:
Química Nova, Vol 35, Iss 11, Pp 2312-2316 (2012)
To assess topical delivery studies of glycoalkaloids, an analytical method by HPLC-UV was developed and validated for the determination of solasonine (SN) and solamargine (SM) in different skin layers, as well as in a topical formulation. The method
Externí odkaz:
https://doaj.org/article/af5b9959aece4e25b35f20e0f0831ad9
Autor:
Wilmer H. Perera, Ion Ghiviriga, Douglas L. Rodenburg, Kamilla Alves, Frank T. Wiggers, Charles D. Hufford, Frank R. Fronczek, Mohamed A. Ibrahim, Ilias Muhammad, Bharathi Avula, Ikhlas A. Khan, James D. McChesney
Publikováno v:
Molecules, Vol 23, Iss 12, p 3328 (2018)
Stevia rebaudiana and its diterpene glycosides are one of the main focuses of food companies interested in developing novel zero calorie sugar substitutes since the recognition of steviol glycosides as Generally Recognized as Safe (GRAS) by the Unite
Externí odkaz:
https://doaj.org/article/471b30a998c54890bc06ff3bb93eae20
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 3, Pp o410-o411 (2013)
Stevioside is a naturally occurring diterpenoid glycoside in Stevia rebaudiana Bertoni. The title compound, C38H60O18·4CH3OH, crystallized as its methanol tetrasolvate. Stevioside consists of an aglycone steviol (a tetracyclic diterpene in which the
Externí odkaz:
https://doaj.org/article/beb3c86198a54c8f835d7e8ba1ee0f07
Autor:
Washim Khan, Yan-Hong Wang, N.P. Dhammika Nanayakkara, H.M.T. Bandara Herath, Narayan D. Chaurasiya, Babu L. Tekwani, Mahmoud A. ElSohly, James D. McChesney, Ikhlas A. Khan, Larry A. Walker
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1213
Primaquine (PQ), a prototype 8-aminoquinoline (8-AQ) drug used to treat malaria, is rapidly metabolized into different inactive and active metabolites. Due to the hemolytic toxicity, the uses of PQ have been confined. To understand its overall metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50d1912eb097debbe68d23ee9270888
https://pubmed.ncbi.nlm.nih.gov/36343612
https://pubmed.ncbi.nlm.nih.gov/36343612
Autor:
Amir E. Wahba, Pier Paolo Claudio, Mahesh Kumar Gundluru, David A. Lewis, James D. McChesney, Douglas L. Rodenburg, Michael L. Coen, Igor Nikoulin, Patrice Penfornis, Steve J. Bannister
Veiled Therapeutics has developed an anticancer technology, TumorSelect® Technology, which combines proprietary anticancer prodrugs and nanotechnology, which takes advantage from current knowledge of human physiology. Tumors have a voracious appetit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::399a1fdf86d4b8ca95ce68cbfd612f94
https://doi.org/10.21203/rs.3.rs-701601/v1
https://doi.org/10.21203/rs.3.rs-701601/v1
