Zobrazeno 1 - 10
of 37
pro vyhledávání: '"JAK2, Janus kinase 2"'
Publikováno v:
Balkan Journal of Medical Genetics, Vol 22, Iss 1, Pp 57-60 (2019)
Myelofibrosis (MF) is characterized by a presence of an extra fibrous tissue in the bone marrow and additional hematopoiesis. The somatic mutation in the Janus kinase 2 (JAK2) gene (V617F) occurs gradually and is detected in about 50.0% of myelofibro
Externí odkaz:
https://doaj.org/article/14dbd66e31384fd2ac81affcdcc2e55a
Akademický článek
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Autor:
Chuyao Liao, Di Wang, Ying Zhang, Zunjian Zhang, Fengguo Xu, Siyuan Qin, Yuxin Zhang, Danting Li, Yuan Tian, Jie Chen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 763-780 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Intestinal toxicity induced by chemotherapeutics has become an important reason for the interruption of therapy and withdrawal of approved agents. In this study, we demonstrated that chemotherapeutics-induced intestinal damage were commonly character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af930bc5ea3c9fbae9d582539b35a5f
https://doi.org/10.1016/j.apsb.2020.07.017
https://doi.org/10.1016/j.apsb.2020.07.017
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 9, Pp 1101-1111 (2020)
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal : SPJ
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease, which is accompanied by progressive joint damage and disability. The intolerability of conventional antirheumatic drugs by some patients necessitates the search for effective antirheuma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955123f7fe28b608ccba43d266079aeb
https://doi.org/10.1016/j.jsps.2020.07.011
https://doi.org/10.1016/j.jsps.2020.07.011
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 196-207 (2020)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Highlights • Clonal hematopoiesis is a common condition in the elderly that can result from the acquisition of somatic mutations in HSPCs that confer a selective advantage and allow for clonal cell expansion. • This clonal population of mutated H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa4a4043fba203b6aa8e576cf452af8
http://www.sciencedirect.com/science/article/pii/S2452302X19302591
http://www.sciencedirect.com/science/article/pii/S2452302X19302591
Autor:
Sano, Soichi, Wang, Ying, Yura, Yoshimitsu, Sano, Miho, Oshima, Kosei, Yang, Yue, Katanasaka, Yasufumi, Min, Kyung-Duk, Matsuura, Shinobu, Ravid, Katya, Mohi, Golam, Walsh, Kenneth
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Clonal hematopoiesis can develop from JAK2V617F mutant cells, but mouse models harboring this mutation are confounded by myeloproliferative disease phenotypes. • To establish a model of JAK2V617F clonal hematopoi
Highlights • Clonal hematopoiesis can develop from JAK2V617F mutant cells, but mouse models harboring this mutation are confounded by myeloproliferative disease phenotypes. • To establish a model of JAK2V617F clonal hematopoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::51a7a3a653ac6f636a4d4ca58778a47a
http://europepmc.org/articles/PMC6834960
http://europepmc.org/articles/PMC6834960
Publikováno v:
Balkan Journal of Medical Genetics, Vol 22, Iss 1, Pp 57-60 (2019)
Balkan Journal of Medical Genetics : BJMG
Balkan Journal of Medical Genetics : BJMG
Myelofibrosis (MF) is characterized by a presence of an extra fibrous tissue in the bone marrow and additional hematopoiesis. The somatic mutation in the Janus kinase 2 (JAK2) gene (V617F) occurs gradually and is detected in about 50.0% of myelofibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c1d3787d6e693f1a43cbae03f3be88
https://doaj.org/article/14dbd66e31384fd2ac81affcdcc2e55a
https://doaj.org/article/14dbd66e31384fd2ac81affcdcc2e55a
Autor:
Jonel Trebicka, Yasuko Iwakiri
Publikováno v:
JHEP Reports
JHEP reports 3(4), 100316 (2021). doi:10.1016/j.jhepr.2021.100316
JHEP reports 3(4), 100316 (2021). doi:10.1016/j.jhepr.2021.100316
JHEP reports 3(4), 100316 (2021). doi:10.1016/j.jhepr.2021.100316
Published by Elsevier, Amsterdam
Published by Elsevier, Amsterdam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817e7f2fa6a8c7f053d31fbdccf64294
http://publikationen.ub.uni-frankfurt.de/files/63083/container.zip
http://publikationen.ub.uni-frankfurt.de/files/63083/container.zip
Autor:
David A. Goukassian, Lahouaria Hadri, Kenneth Fish, Malik Bisserier, Walid Hamouche, Abrisham Eskandari, Agnieszka Brojakowska
Publikováno v:
Journal of Molecular and Cellular Cardiology
The first confirmed case of novel Coronavirus Disease 2019 (COVID-19) in the United States was reported on January 20, 2020. As of November 24, 2020, close to 12.2 million cases of COVID-19 was confirmed in the US, with over 255,958 deaths. The rapid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d439cbf7ea2e5b22768fd838287da5
https://pubmed.ncbi.nlm.nih.gov/33373644
https://pubmed.ncbi.nlm.nih.gov/33373644
Autor:
Ergun Pinarbasi, Merve Nur Aydemir, Mahir Budak, Nilgun Cekin, Ertan Mahir Korkmaz, Habes Bilal Aydemir
Publikováno v:
Gene Reports
Recently an outbreak that emerged in Wuhan, China in December 2019, spread to the whole world in a short time and killed >1,410,000 people. It was determined that a new type of beta coronavirus called severe acute respiratory disease coronavirus type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74b1417480891b038305389c4712706
https://pubmed.ncbi.nlm.nih.gov/33398248
https://pubmed.ncbi.nlm.nih.gov/33398248