Zobrazeno 1 - 10
of 14
pro vyhledávání: '"JAK-STAT signaling cascade"'
Autor:
Tze Chiew Christie Soo, Subha Bhassu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258655 (2021)
PLoS ONE, Vol 16, Iss 10 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258655 (2021)
Diseases have remained the major issue for shrimp aquaculture industry for decades by which different shrimp species demonstrated alternative disease resistance or tolerance. However, there had been insufficient studies on the underlying host mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc58eda1386be3f382d1d87b18cf87d3
http://europepmc.org/articles/PMC8519450
http://europepmc.org/articles/PMC8519450
Autor:
Sudipta Halder, Gaurab Ghosh, Girish Deshpande, Purbasa Dasgupta, Sayan Acharjee, Ritabrata Ghosh, Mohit Prasad, Aresh Sahu, Susnata Karmakar
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 17, Iss 8, p e1009685 (2021)
PLoS Genetics, Vol 17, Iss 8, p e1009685 (2021)
Gap junction (GJ) proteins, the primary constituents of GJ channels, are conserved determinants of patterning. Canonically, a GJ channel, made up of two hemi-channels contributed by the neighboring cells, facilitates transport of metabolites/ions. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe9fead0775404ed5fe517a5e34bc7c0
https://doi.org/10.1371/journal.pgen.1009685
https://doi.org/10.1371/journal.pgen.1009685
Autor:
Lorenza Borin, Francesco Spina, Alessandra Trojani, Mauro Turrini, Chiara Elena, Ester Pungolino, Cristina Bucelli, Roberto Cairoli, Giacomo Baruzzo, Alessandra Perego, Pierangelo Spedini, Gabriella De Canal, Mariella D'Adda, Maria Luisa Latargia, Barbara Di Camillo, Alessandra Dal Molin, Maria Cristina Carraro, Michela Anghilieri, Milena Lodola, Giuseppe Rossi, Simona Malato, Salvatore Artale, Enrica Morra, Alessandra Iurlo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0218444 (2019)
PLoS ONE, Vol 14, Iss 7, p e0218444 (2019)
Chronic myeloid leukemia (CML) is characterized by the constitutive tyrosine kinase activity of the oncoprotein BCR-ABL1 in myeloid progenitor cells that activates multiple signal transduction pathways leading to the leukemic phenotype. The tyrosine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af75033faa7817e3679cc53f005d79cd
http://europepmc.org/articles/PMC6638825
http://europepmc.org/articles/PMC6638825
Publikováno v:
PLoS Genetics, Vol 15, Iss 3, p e1007931 (2019)
PLoS Genetics
PLoS Genetics
Dipteran insects transmit serious diseases to humans, often in the form of trypanosomatid parasites. To accelerate research in more difficult contexts of dipteran-parasite relationships, we studied the interaction of the model dipteran Drosophila mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f6bc763321cbec9544aa35acb44d07
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Ayaz Ahmed, Safina Ghaffar, Shabbir Khan Afridi, Rahman M. Hafizur, Meha Fatima Aftab, Munazza Murtaza, Gulnaz Khan, Rizwana S. Waraich
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0178910 (2017)
PLoS ONE, Vol 12, Iss 6, p e0178910 (2017)
Several members of cucurbitaceae family have been reported to regulate growth of cancer by interfering with STAT3 signaling. In the present study, we investigated the unique role and molecular mechanism of cucurbitacins (Cucs) in reducing symptoms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7e0cbd9d52816418452e2747e63b26
http://europepmc.org/articles/PMC5466318
http://europepmc.org/articles/PMC5466318
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0186004 (2017)
PLoS ONE, Vol 12, Iss 10, p e0186004 (2017)
The PubMed database offers an extensive set of publication data that can be useful, yet inherently complex to use without automated computational techniques. Data repositories such as the Genomic Data Commons (GDC) and the Gene Expression Omnibus (GE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c109d3b39bab28e3a2ae9f3ea66bb42a
https://pubmed.ncbi.nlm.nih.gov/29049295
https://pubmed.ncbi.nlm.nih.gov/29049295
Autor:
Michelle Petri, Yushi Liu, Daniel J. Wallace, Robert W Hoffman, Xiong Liu, Thomas Dörner, Bradley B. Miller, Brian J. Eastwood, Richard E. Higgs, Ernst R. Dow, Yupeng Li
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0225651 (2019)
PLoS ONE, Vol 14, Iss 12, p e0225651 (2019)
Systemic lupus erythematosus (SLE) is a chronic, remitting, and relapsing, inflammatory disease involving multiple organs, which exhibits abnormalities of both the innate and adaptive immune responses. A limited number of transcriptomic studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb71b48cef5323c6c0023ee22ae3cb3
https://doi.org/10.1371/journal.pone.0225651
https://doi.org/10.1371/journal.pone.0225651
Autor:
Qingxu Zheng, Yun Zheng, Xin Zhang, Xiangqi Hao, Pei Zhou, Weijie Zeng, Lifang Wang, Shoujun Li, Guihong Zhang, Xi Lin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 10, p e0185698 (2017)
PLoS ONE, Vol 12, Iss 10, p e0185698 (2017)
Feline panleukopenia is a common contagious disease with high morbidity and mortality. At present, feline parvovirus (FPV) and canine parvovirus (CPV) variants are the pathogens of feline panleukopenia. Many studies have shown that miRNAs are involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73fa3544bc9f7e6c719fad251628a7f
https://pubmed.ncbi.nlm.nih.gov/29049413
https://pubmed.ncbi.nlm.nih.gov/29049413
Autor:
Begoña Oliver-Martos, Patricia Urbaneja, Antonio León, Oscar Fernández, Miguel Guerrero, Jose Luis Rodriguez-Bada, María Jesús Pinto-Medel, Laura Leyva, Isaac Hurtado-Guerrero
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170031 (2017)
PLoS ONE
PLoS ONE
Interferon beta (IFNß) is a common treatment used for multiple sclerosis (MS) which acts through the activation of the JAK-STAT pathway. However, this therapy is not always effective and currently there are no reliable biomarkers to predict therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b18663091dcacfc3b661d3532e4712
http://europepmc.org/articles/PMC5245989?pdf=render
http://europepmc.org/articles/PMC5245989?pdf=render
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 1, p e1006542 (2017)
PLoS Genetics, Vol 13, Iss 1, p e1006542 (2017)
Intercellular communication mediated by gap junction (GJ) proteins is indispensable during embryogenesis, tissue regeneration and wound healing. Here we report functional analysis of a gap junction protein, Innexin 2 (Inx2), in cell type specificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de7b4fcbd0c2eef66bdf9d62b674a87
https://pubmed.ncbi.nlm.nih.gov/28114410
https://pubmed.ncbi.nlm.nih.gov/28114410