Zobrazeno 1 - 10
of 97
pro vyhledávání: '"JAK/STAT3 signaling pathway"'
Autor:
Binhui Xie, Yuankang Xie, Cuifu Fang, Baiyin Zhong, Rong Ye, Jianhong Zhang, Qingquan Liu, Heping Li
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Previous studies have shown that Family with sequence similarity 134 member B (FAM134B) was involved in the occurrence and development of malignancy, however, the function and molecular mechanism of FAM134B in Hepatocellular Carci
Externí odkaz:
https://doaj.org/article/1b54f97365cf4367aa0f71deec20798c
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTObjectives Although cytarabine (AraC) has greatly contributed to improving the prognosis of patients with acute myeloid leukemia (AML), many patients developed drug resistance and eventually succumbed to AML. Thus, resistance to AraC is a maj
Externí odkaz:
https://doaj.org/article/c5522958013048b6b0012a8bb426f6ad
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 12, Pp n/a-n/a (2022)
Abstract Introduction This study aimed to investigate the effect of etanercept in psoriasis and its underlying mechanism. Methods Female mice were treated with imiquimod (IMQ) to induce psoriasis, and intraperitoneally administered etanercept (0.1–
Externí odkaz:
https://doaj.org/article/532c1913f21f4140b05d4bb3cd71470e
Publikováno v:
Marine Drugs, Vol 21, Iss 4, p 218 (2023)
The JAK/STAT3 signaling pathway is aberrantly hyperactivated in many cancers, promoting cell proliferation, survival, invasiveness, and metastasis. Thus, inhibitors targeting JAK/STAT3 have enormous potential for cancer treatment. Herein, we modified
Externí odkaz:
https://doaj.org/article/f9f1d5ddb9834265b1d3cb10085ad02e
Autor:
Jia‐Wen Wang, Yi‐Bin Pan, Yong‐Qing Cao, Chen Wang, Wei‐Dong Jiang, Wei‐Feng Zhai, Jin‐Gen Lu
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 36, Iss 4, Pp 257-264 (2020)
Abstract Inflammatory bowel disease (IBD) is a chronic, recurrent gastrointestinal inflammation that affects millions of people around the world. Loganin, an iridoid glycoside, has shown the anti‐inflammatory effects. However, the effect of loganin
Externí odkaz:
https://doaj.org/article/714af673b528475c9ec473e66ff7e821
Akademický článek
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Autor:
Leitao Sun, Shuning Ding, Qi Luo, Peipei Wang, Xiao Yang, Linqin Wu, Yangfan Chen, Xueer Zheng, Hang Zhang, Li Yuan, Shanming Ruan, Changsheng Xie
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
As one of the most common neoplasms globally, lung cancer (LC) is the leading cause of cancer-related mortality. Recurrence and metastasis negatively influencing therapeutic efficacy and overall survival demand new strategies in LC treatment. The adv
Externí odkaz:
https://doaj.org/article/73a0cd2e1a544800afded5e96fd0ce52
Publikováno v:
Di-san junyi daxue xuebao, Vol 41, Iss 17, Pp 1642-1648 (2019)
Objective To detect the expression level of aldehyde dehydrogenase 1 family member A3 (ALDH1A3) in pancreatic cancer and adjacent tissues, and to study its specific mechanism involved in the regulation of invasion of pancreatic cancer cells. Methods
Externí odkaz:
https://doaj.org/article/4e40733289cd4850ab93f52ffadfaafa
Autor:
Xiao-Feng Xu, Feng Gao, Jian-Jiang Wang, Cong Long, Xing Chen, Lan Tao, Liu Yang, Li Ding, Yong Ji
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background Cancer stem cells (CSCs), drug-resistant cancer cell subsets, are known to be responsible for tumor metastasis and relapse. The JAK/STAT pathway, activated by SH2 domain, is known to regulate the tumor growth in gastric cancer (GC
Externí odkaz:
https://doaj.org/article/6f9d12490eaa4766ad935c9bc52d4525
Akademický článek
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