Zobrazeno 1 - 10
of 46
pro vyhledávání: '"JADEL M. KRATZ"'
Autor:
Brian W. Slafer, Marco A. Dessoy, Ramon G. de Oliveira, Maria C. Mollo, Eun Lee, An Matheeussen, Louis Maes, Guy Caljon, Leonardo L. G. Ferreira, Renata Krogh, Adriano D. Andricopulo, Luiza R. Cruz, Charles E. Mowbray, Jadel M. Kratz, Luiz C. Dias
Publikováno v:
ACS Omega, Vol 9, Iss 20, Pp 22360-22370 (2024)
Externí odkaz:
https://doaj.org/article/181f8460774544aa8d922443939c65c7
Autor:
Amanda F. Francisco, Gong Chen, Wen Wang, Melissa L. Sykes, Fanny Escudié, Ivan Scandale, Francisco Olmo, David M. Shackleford, Bilal Zulfiqar, Jadel M. Kratz, Thao Pham, Jessica Saunders, Meiyu Hu, Vicky M. Avery, Susan A. Charman, John M. Kelly, Eric Chatelain
Publikováno v:
Frontiers in Tropical Diseases, Vol 4 (2023)
The repurposing of approved drugs is an appealing method to fast-track the development of novel therapies for neglected diseases. Amiodarone and dronedarone, two approved antiarrhythmic agents, have been reported to have potential for the management
Externí odkaz:
https://doaj.org/article/ef8763e0491744609722bd57eeca7461
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that endangers almost 70 million people worldwide. The only two drugs that are currently approved for its treatment, benznidazole and nifurtimox, have c
Externí odkaz:
https://doaj.org/article/c76f51040f3544ce95ce570ee07e311c
Autor:
Benjamin Kirchweger, Jadel M. Kratz, Angela Ladurner, Ulrike Grienke, Thierry Langer, Verena M. Dirsch, Judith M. Rollinger
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
The G protein-coupled bile acid receptor (GPBAR1) has been recognized as a promising new target for the treatment of diverse diseases, including obesity, type 2 diabetes, fatty liver disease and atherosclerosis. The identification of novel and potent
Externí odkaz:
https://doaj.org/article/c0afcca1828e4f18980f618a8eb4299a
Autor:
SIMONE Q. OLIVEIRA, JADEL M. KRATZ, VITOR C. CHAVES, TATIANA R. GUIMARÃES, DANIELLE T.M. COSTA, SAPFO DIMITRAKOUDI, ARGYRO VONTZALIDOU, SÉRGIO A.L. BORDIGNON, CESAR P. SIMIONATO, MÁRIO STEINDEL, FLÁVIO H. REGINATTO, CLÁUDIA M.O. SIMÕES, ELOIR P. SCHENKEL
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 91, Iss 3
Abstract: Aristolochia triangularis Cham., is one of the most frequently used medicinal plant in Southern Brazil. Preparations containing the leaves and/or stems are traditionally used as anti-inflammatory, diuretic, as well as antidote against snake
Externí odkaz:
https://doaj.org/article/516d57b4df364d9593119b1d9545a71a
Autor:
Jadel M Kratz, Karolina R Gonçalves, Lavínia MD Romera, Carolina Borsoi Moraes, Paula Bittencourt-Cunha, Sergio Schenkman, Eric Chatelain, Sergio Sosa-Estani
Publikováno v:
Memórias do Instituto Oswaldo Cruz, Volume: 117, Article number: e200501, Published: 23 MAY 2022
Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi. There is an urgent need for safe, effective, and accessible new treatments since the currently approved drugs have serious limitations. Drug developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b8b2af06a6ca34e48c8c088c47de41
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762022000100206&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762022000100206&lng=en&tlng=en
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 9 (2021)
Frontiers in Chemistry, Vol 9 (2021)
Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that endangers almost 70 million people worldwide. The only two drugs that are currently approved for its treatment, benznidazole and nifurtimox, have c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df6c0084a57091ece23e058c5ccfc9d
https://pubmed.ncbi.nlm.nih.gov/34778217
https://pubmed.ncbi.nlm.nih.gov/34778217
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Paediatrics Publications
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Paediatrics Publications
Introduction: Chagas disease (CD) is one of the most neglected public health problems in the Americas, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2523888eeb85eaae99629a89fbd1b8
https://doi.org/10.1080/17512433.2018.1509704
https://doi.org/10.1080/17512433.2018.1509704
Autor:
Judith M. Rollinger, Sarah K. Oettl, Steffen Hering, Christina E. Mair, Daniela Schuster, Jadel M. Kratz, Olaf Scheel, Priyanka Saxena
Publikováno v:
Planta Medica. 81:S1-S381
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2152779639331f0981eb5994fda74999
https://doi.org/10.1055/s-0036-1597035
https://doi.org/10.1055/s-0036-1597035
Autor:
Paul J. Koovits, Guy Caljon, Charles E. Mowbray, Luiz C. Dias, Louis Maes, Jadel M. Kratz, Marco A. Dessoy, An Matheeussen
Publikováno v:
Bioorganic and medicinal chemistry letters
The structure-activity relationship of a 4-Azaindole-2-piperidine compound selected from GlaxoSmithKline’s recently disclosed open-resource “Chagas box” and possessing moderate activity against Trypanosoma cruzi, the parasite responsible for Ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03546ec15a533b242294aa2d60c4cb2
https://pubmed.ncbi.nlm.nih.gov/31706667
https://pubmed.ncbi.nlm.nih.gov/31706667