Zobrazeno 1 - 10
of 19
pro vyhledávání: '"JA McKinna"'
Autor:
Stanley W. Ashley, I. E. Smith, G. Walsh, S. R. Ebbs, Michael J. Baum, JA McKinna, P. A. Ellis, Npm Sacks
Publikováno v:
Journal of Clinical Oncology. 16:107-114
PURPOSE This study aimed to identify clinical factors that are of prognostic significance or that predict for subsequent treatment outcome in patients with large operable breast cancer treated with primary chemotherapy (PCT) at our institution. METHO
Autor:
JA McKinna, NM Sacks, Janine Salter, Mitchell Dowsett, K.A. McLennan, Michael Baum, I.E. Smith, S.R.D. Johnston
Publikováno v:
The Breast. 2:93-99
Over-expression of c-erbB2 in human breast cancer correlates with a poor prognosis and increased tumour aggressiveness. Recent in-vitro evidence has suggested that expression of c-erbB2 may be hormonally regulated, and in particular that oestrogen-wi
Autor:
I. E. Smith, A. G. Nash, A. L. Jones, T. J. Powles, Matthew Law, JA McKinna, R. C. Coombes, H. T. Ford, A. Tidy, Doug Easton
Publikováno v:
Journal of Clinical Oncology. 10:1547-1552
PURPOSE The study purpose was to evaluate aminoglutethimide (AG) as adjuvant therapy in patients with primary node-positive breast cancer in a randomized double-blind placebo-controlled trial. PATIENTS AND METHODS In a multicenter trial, 354 postmeno
Publikováno v:
European journal of cancer (Oxford, England : 1990). (12)
84 patients with large operable breast cancer have been treated with primary medical chemotherapy rather than mastectomy in three sequential studies. 86% had tumours greater than 4 cm in diameter; median diameter was 6 cm (range 1–12). Median age w
Autor:
Alison Jones, A Tidy, JC Gazer, M Law, H. T. Ford, I. E. Smith, A. G. Nash, T. J. Powles, Mitchell Dowsett, Doug Easton, R.C. Coombes, JA McKinna
Publikováno v:
The Breast. 1:160-161
Publikováno v:
The Breast. 1:162
Autor:
NM Sacks, K. Maclennan, S.R.D. Johnston, I. E. Smith, Mitchell Dowsett, JA McKinna, Janine Salter
Publikováno v:
The Breast. 1:166
Publikováno v:
The Breast. 1:154
Autor:
A Kurkure, JA McKinna, L Carr, I.E. Smith, T. Bozek, J.-C. Gazet, R. Stuart-Harris, Mitchell Dowsett, S.L. Jeffcoate
Publikováno v:
The Lancet. 324:604-607
The clinical and endocrine effects of low-dose aminoglutethimide without hydrocortisone in patients with advanced breast cancer were investigated. In a dose escalation study low-dose aminoglutethimide alone (62.5-125 mg twice daily) was as effective
Autor:
TJ Powles, JR Hardy, SE Ashley, GM Farrington, D Cosgrove, JB Davey, M Dowsett, JA McKinna, AG Nash, HD Sinnett, CR Tillyer, JG Treleaven
Publikováno v:
British Journal of Cancer
Epidemiological and experimental evidence indicates that oestrogens are involved in the carcinogenic promotion of human breast cancer. We have undertaken a pilot trial of tamoxifen, an anti-oestrogen, compared to placebo given to 200 women at a high