Zobrazeno 1 - 10
of 311
pro vyhledávání: '"JA Ledbetter"'
Publikováno v:
Blood. 82:1212-1220
We have previously observed that ionizing radiation induces tyrosine phosphorylation in human B-lymphocyte precursors by stimulation of unidentified tyrosine kinases and this phosphorylation is substantially augmented by vanadate. Ionizing radiation
Autor:
KG Schlechte, W. C. Van Voorhis, Ann M. Waltersdorph, Seymour J. Klebanoff, S Olszowski, JA Ledbetter
Publikováno v:
Blood. 80:225-234
stimulating factor (GM-CSF), formylmethionyl-leucyl-phenylalanine (FMLP), opsonized zymosan, and lipopolysaccharide (LPS), as compared with cells comparably preincubated in the absence of IFN-y. The decline in the staphylocidal activity of the stored
Autor:
Fatih M. Uckun, Haissig S, Ja, Ledbetter, Fidler P, Myers DE, Kuebelbeck V, Weisdorf D, Gajl-Peczalska K, Jh, Kersey, Nk, Ramsay
Publikováno v:
Europe PubMed Central
Sequential immunophenotypes of bone marrow (BM) and peripheral blood (PBL) lymphoid cells from 15 B-lineage acute lymphoblastic leukemia (ALL) patients who underwent autologous bone marrow transplantation (BMT) during complete remission were determin
Publikováno v:
Europe PubMed Central
The heavy (VH) and light (VL) chain variable regions of the murine anti-human CD20 mAb 1F5 were cloned, and four single-chain Ab (scFv) molecules were constructed using linker peptides of variable lengths to join the VH and VL domains. Three construc
Publikováno v:
Europe PubMed Central
CD20 is a nonglycosylated 33 to 37 kD phosphoprotein involved in B-cell signaling that subserves important functions in the regulation of B-cell proliferation and differentiation. In addition, this B-cell surface antigen has been shown recently to be
Autor:
Lg, Lum, Id, Joshi, Sc, Galoforo, Abella E, Karanes C, Ratanatharathorn V, Kirk Schultz, Jp, Uberti, Ll, Sensenbrenner, Ja, Ledbetter
Publikováno v:
Europe PubMed Central
Recent studies show that costimulation of T cells with anti-CD28 Mab (anti-CD28) enhances anti-CD3 Mab (anti-CD3)-induced proliferative responses and cytokine production. This study determines if coactivation with anti-CD3 and anti-CD28 corrects defe
Publikováno v:
Europe PubMed Central
It has been proposed that during T cell receptor antigen recognition, CD4- or CD8-p56lck molecules interact with the T cell antigen receptor-CD3 complex (TCR-CD3) to phosphorylate various undefined substrates, which then initiate signal transduction
Autor:
Fatih M. Uckun, Jh, Kersey, Da, Vallera, Ja, Ledbetter, Weisdorf D, Myers DE, Haake R, Nk, Ramsay
Publikováno v:
Europe PubMed Central
Fourteen patients with high-risk T-lineage acute lymphoblastic leukemia (ALL) in complete remission underwent autologous bone marrow transplantation (BMT) in an attempt to eradicate their residual disease burden. A combined immunochemotherapy protoco
Autor:
FM Uckun, W Jaszcz, JL Ambrus, AS Fauci, K Gajl-Peczalska, CW Song, MR Wick, DE Myers, K Waddick, JA Ledbetter
Publikováno v:
Blood. 71:13-29
Extensive immunologic surface marker analyses and binding competition assays demonstrated that B43 monoclonal antibody (MoAb) is a new member of the CD19 cluster that recognizes the same surface epitope as several other anti-CD19 MoAbs. We used B43 M
Autor:
Fatih M. Uckun, Jaszcz W, Jl, Ambrus, As, Fauci, Gajl-Peczalska K, Cw, Song, Wick MR, Myers DE, Waddick K, Ja, Ledbetter
Publikováno v:
Europe PubMed Central
Extensive immunologic surface marker analyses and binding competition assays demonstrated that B43 monoclonal antibody (MoAb) is a new member of the CD19 cluster that recognizes the same surface epitope as several other anti-CD19 MoAbs. We used B43 M