Intracellular localization of glycosyl-phosphatidylinositol-anchored CD67 and FcRIII (CD16) in affected neutrophil granulocytes of patients with paroxysmal nocturnal hemoglobinuria

Autor: CR Jost, ML Gaillard, JA Fransen, MR Daha, LA Ginsel

Publikováno v: Blood. 78(11)

Immunoelectron microscopical studies performed in healthy human neutrophils showed the presence of glycosyl-phosphatidylinositol (GPI)- linked CD67 in granules. The use of immunogold double-labeling of CD67 and lactoferrin (LF; as marker for specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadcc094ca36ad99643d53c12b8873d6
https://pubmed.ncbi.nlm.nih.gov/1835413

Intracellular localization and de novo synthesis of FcRIII in human neutrophil granulocytes

Autor: CR Jost, TW Huizinga, R de Goede, JA Fransen, PA Tetteroo, MR Daha, LA Ginsel

Publikováno v: Blood. 75(1)

Immunoelectron microscopic studies in human neutrophils showed that FcRIII was present on the plasma membrane, in the Golgi complex, and in many small vesicles (120 to 180 nm). FcRIII was not found in specific or azurophilic granules as shown by immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7814159418618a289a934d4471ef7ada
https://pubmed.ncbi.nlm.nih.gov/2136801

Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes.

Autor: Lachmandas E; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands., Boutens L; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, 6708 WE, Wageningen, The Netherlands., Ratter JM; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, 6708 WE, Wageningen, The Netherlands., Hijmans A; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands., Hooiveld GJ; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, 6708 WE, Wageningen, The Netherlands., Joosten LA; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands., Rodenburg RJ; Department of Pediatrics, Radboud Center for Mitochondrial Medicine, 774 Translational Metabolic Laboratory, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands., Fransen JA; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 1105 AZ, Nijmegen, The Netherlands., Houtkooper RH; Laboratory Genetic Metabolic Diseases, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., van Crevel R; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands., Netea MG; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands., Stienstra R; Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, 6708 WE, Wageningen, The Netherlands.

Publikováno v: Nature microbiology [Nat Microbiol] 2016 Dec 19; Vol. 2, pp. 16246. Date of Electronic Publication: 2016 Dec 19.

NAMPT-mediated salvage synthesis of NAD+ controls morphofunctional changes of macrophages.

Autor: Venter G; Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands., Oerlemans FT; Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands., Willemse M; Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands., Wijers M; Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands., Fransen JA; Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands., Wieringa B; Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands.

Publikováno v: PloS one [PLoS One] 2014 May 13; Vol. 9 (5), pp. e97378. Date of Electronic Publication: 2014 May 13 (Print Publication: 2014).

Intracellular NAD(H) levels control motility and invasion of glioma cells.

Autor: van Horssen R; Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences (NCMLS), Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. r.vanhorssen@ncmls.ru.nl, Willemse M, Haeger A, Attanasio F, Güneri T, Schwab A, Stock CM, Buccione R, Fransen JA, Wieringa B

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2013 Jun; Vol. 70 (12), pp. 2175-90. Date of Electronic Publication: 2013 Jan 10.