Výsledky vyhledávání

Activation signals leading to proliferation of normal and leukemic CD3+ large granular lymphocytes

Autor: JA Aprile, M Russo, MS Pepe, TP Jr Loughran

Publikováno v: Blood. 78:1282-1285

The activation signals leading to proliferation of normal and leukemic CD3+ large granular lymphocytes (LGL) were studied in vitro. Anti-CD3 monoclonal antibody (MoAb) alone (P less than .01) and recombinant interleukin-2 (IL-2) alone (P less than .0

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f10701c9e81643dd0e88ee923c08bc5
https://doi.org/10.1182/blood.v78.5.1282.bloodjournal7851282

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Rearrangement and expression of T-cell receptor genes in large granular lymphocyte leukemia

Autor: TP Jr Loughran, G Starkebaum, JA Aprile

Publikováno v: Blood. 71:822-824

Ten patients with large granular lymphocyte (LGL) leukemia were studied for rearrangement and expression of T cell receptor (TCR) genes. Eight patients with CD3+ LGL proliferation had unique TCR beta-gene rearrangements, supporting a clonal process.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f22f2e7e95e1c843f1469f7bfe5e40ac
https://doi.org/10.1182/blood.v71.3.822.bloodjournal713822

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Akademický článek

Activation signals leading to proliferation of normal and leukemic CD3+ large granular lymphocytes.

Autor: Aprile JA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98104., Russo M, Pepe MS, Loughran TP Jr

Publikováno v: Blood [Blood] 1991 Sep 01; Vol. 78 (5), pp. 1282-5.

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Akademický článek

Interleukin-2 receptor monoclonal antibodies have no effect on anti-CD3 monoclonal antibody-mediated cytotoxicity in CD3+ leukemic large granular lymphocytes.

Autor: Yoon HJ; Fred Hutchinson Cancer Research Center, Seattle, Washington 98104., Aprile JA, Loughran TP Jr

Publikováno v: Cellular immunology [Cell Immunol] 1990 Dec; Vol. 131 (2), pp. 404-8.

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Akademický článek

Anti-CD3 monoclonal antibody-mediated cytotoxicity occurs through an interleukin-2-independent pathway in CD3+ large granular lymphocytes.

Autor: Loughran TP Jr; Fred Hutchinson Cancer Research Center, Seattle, WA 98104., Aprile JA, Ruscetti FW

Publikováno v: Blood [Blood] 1990 Feb 15; Vol. 75 (4), pp. 935-40.

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Akademický článek

Rearrangement and expression of T-cell receptor genes in large granular lymphocyte leukemia.

Autor: Loughran TP Jr; Fred Hutchinson Cancer Research Center, Department of Medicine, University of Washington School of Medicine, Seattle 98104., Starkebaum G, Aprile JA

Publikováno v: Blood [Blood] 1988 Mar; Vol. 71 (3), pp. 822-4.

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