Amitriptyline prolongs the antihyperalgesic effect of 2Hz electroacupuncture in mononeuropathic rats

Autor: Rafael Sobrano Fais, J.W.S. Silveira, William Alves do Prado, G.M. Reis, Quintino Moura Dias, A.C. Rossaneis

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Amitriptyline and electroacupuncture (EA) have been used in the management of neuropathic pain. This study examines whether the use of an intraperitoneal injection of amitriptyline changes the effectiveness of EA to reduce neuropathic pain in rats. C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dac29020a3e48dcac9a4907ed64707
https://doi.org/10.1016/j.arthe.2013.03.001

Antinociceptive Effect of Stimulating the Occipital or Retrosplenial Cortex in Rats

Autor: J.W.S. Silveira, Wiliam A. Prado, Norberto Garcia-Cairasco, G.M. Reis, Quintino Moura Dias, Flávio Del Vecchio

Publikováno v: The Journal of Pain. 11:1015-1026

A role for the occipital or retrosplenial cortex in nociceptive processing has not been demonstrated yet, but connections from these cortices to brain structures involved in descending pain-inhibitory mechanisms were already demonstrated. This study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29119072f24f5980e9efed7a0a505d1f
https://doi.org/10.1016/j.jpain.2010.01.269

Protective Effects of Cannabidiol on Lesion-Induced Intervertebral Disc Degeneration

Autor: Vitor Castania, A.C. Issy, Elaine Aparecida Del Bel, Marcello Henrique Nogueira-Barbosa, Francisco Silveira Guimarães, Carlos Ernesto Garrido Salmon, Helton Luiz Aparecido Defino, J.W.S. Silveira

Publikováno v: PLoS ONE
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS ONE, Vol 9, Iss 12, p e113161 (2014)

Disc degeneration is a multifactorial process that involves hypoxia, inflammation, neoinnervation, accelerated catabolism, and reduction in water and glycosaminoglycan content. Cannabidiol is the main non-psychotropic component of the Cannabis sativa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb77114c62f7ced0f73f6acf7280238
http://europepmc.org/articles/PMC4269422

Amitriptyline converts non-responders into responders to low-frequency electroacupuncture-induced analgesia in rats

Autor: J.W.S. Silveira, Quintino Moura Dias, A.C. Rossaneis, Wiliam A. Prado, Rafael Sobrano Fais, G.M. Reis

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Aims The purpose of this study was to examine whether the use of intraperitoneal or intrathecal amitriptyline combined with electroacupuncture modifies the tail-flick reflex and incision pain in rats that normally do not have analgesia to electroacup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1e4a1eba15a2941d98617502d2cba5
https://pubmed.ncbi.nlm.nih.gov/22677436

Serotonin receptors are involved in the spinal mediation of descending facilitation of surgical incision-induced increase of Fos-like immunoreactivity in rats

Autor: Quintino Moura Dias, Elaine Aparecida Del Bel, J.W.S. Silveira, Wiliam A. Prado

Publikováno v: Molecular Pain, Vol 6, Iss 1, p 17 (2010)
Molecular Pain

Background: Descending pronociceptive pathways may be implicated in states of persistent pain. Paw skin incision is a well-established postoperative pain model that causes behavioral nociceptive responses and enhanced excitability of spinal dorsal ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f131f31dbb8dfc81dd69229a6c3e4728
http://www.molecularpain.com/content/6/1/17