Výsledky vyhledávání - "J.W. van Oostveen"

Stability and prognostic influence of FLT3 mutations in paired and relapsed AML samples

Autor: Gertjan J.L. Kaspers, Bianca F. Goemans, Nancy Boeckx, Corine J. Hess, S Corthals, Dirk Reinhardt, Karel Hählen, J.W. van Oostveen, Jacqueline Cloos, Gerrit-Jan Schuurhuis, D de Lange, Quinten Waisfisz, U. Creutzig, Ch. M. Zwaan

Publikováno v: Cloos, J, Goemans, B F, Hess, C J, van Oostveen, J W, Waisfisz, Q, Corthals, S, de lange, D, Boeckx, N, Hahlen, K, Reinhardt, D, Creutzig, U, Schuurhuis, G J, Zwaan, C M & Kaspers, G J L 2006, ' Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples ', Leukemia, vol. 20, no. 7, pp. 1217-1220 . https://doi.org/10.1038/sj.leu.2404246
Leukemia, 20(7), 1217-1220. Nature Publishing Group
Leukemia, 20, 1217-1220. Nature Publishing Group

In acute myeloid leukemia (AML), activating mutations in the fms-like tyrosine kinase 3 (FLT3) gene predict poor prognosis. We determined FLT3 internal tandem duplications (FLT3/ITD) and D835 point mutations in paired initial and relapse samples from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71f03a88a9150a558ab887ade7373ad
https://doi.org/10.1038/sj.leu.2404246

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Proteoglycans on bone marrow endothelial cells bind and present SDF-1 towards hematopoietic progenitor cells

Autor: J.J. Zwaginga, Angelika M. Dräger, Tanja Netelenbos, Peter C. Huijgens, Floortje L. Kessler, J. van den Born, P.A. Merle, Sonja Zweegman, J.W. van Oostveen

Publikováno v: Leukemia, 17(1), 175-184. Nature Publishing Group
Netelenbos, T, van den Born, J, Kessler, F L, Zweegman, S, Merle, P A, van Oostveen, J W, Zwaginga, J J, Huijgens, P C & Dräger, A M 2003, ' Proteoglycans on bone marrow endothelial cells bind and present SDF-1 towards hematopoietic progenitor cells ', Leukemia, vol. 17, no. 1, pp. 175-184 . https://doi.org/10.1038/sj.leu.2402738

Recognition events between hematopoietic progenitor cells (HPC) and bone marrow endothelial cells (BMEC) initiate homing of HPC to the bone marrow. The chemokine SDF-1 is present on BMEC and plays a crucial role in bone marrow engraftment. We studied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4ceebc12c7dcf4e4b3cc5587684981
https://doi.org/10.1038/sj.leu.2402738

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Molecular analysis of hematopoietic colonies derived from chronic myeloid leukemia patients: interphase fluorescence in situ hybridization compared with RT-PCR

Autor: A.P. Theijsmeijer, Gert J. Ossenkoppele, S.F.T. Thijsen, M. M. A. C. Langenhuijsen, J.W. van Oostveen, Gerrit-Jan Schuurhuis

Publikováno v: Leukemia. 11:301-305

In this study we compared interphase fluorescence in situ hybridization (I-FISH) with reverse transcription polymerase chain reaction (RT-PCR) for the molecular analysis of hematopoietic colonies derived from patients with chronic myeloid leukemia (C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e55ba808b71946fcae495100ad050b
https://doi.org/10.1038/sj.leu.2400563

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Effects of bryostatin-1 on chronic myeloid leukaemia-derived haematopoietic progenitors

Autor: J.W. van Oostveen, S.F.T. Thijsen, A.P. Theijsmeijer, K G van der Hem, Gert J. Ossenkoppele, Joan H. Odding, Gerrit-Jan Schuurhuis, Angelika M. Dräger

Publikováno v: British Journal of Cancer
Thijsen, S F T, Schuurhuis, G J, van Oostveen, J W, Theijsmeijer, A P, van der Hem, K G, Odding, J H, Draeger, A M & Ossenkoppele, G J 1999, ' Effects of bryostatin-1 on chronic myeloid leukaemia-derived haematopoietic progenitors ', British Journal of Cancer, vol. 79, pp. 1406-1412 . https://doi.org/10.1038/sj.bjc.6690225
British Journal of Cancer, 79, 1406-1412. Nature Publishing Group

Bryostatin-1 belongs to the family of macrocyclic lactones isolated from the marine bryozoan Bugula neritina and is a potent activator of protein kinase C (PKC). Bryostatin has been demonstrated to possess both in vivo and in vitro anti-leukaemic pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82305a6e5f696b887746eb6f8f5a7090
https://pubmed.ncbi.nlm.nih.gov/10188883

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Secondary imatinib resistance associated with an aberrant bcr-abl fusion gene

Autor: Andreas Hochhaus, Jeroen Janssen, J.W. van Oostveen, Gerrit-Jan Schuurhuis, Quinten Waisfisz, Gert J. Ossenkoppele

Publikováno v: Leukemia, 18(5), 1020-1021. Nature Publishing Group
Janssen, JJWM, Hochhaus, A, van Oostveen, JW, Waisfisz, Q, Schuurhuis, GJ & Ossenkoppele, GJ 2004, ' Secondary imatinib resistance associated with an aberrant bcr-abl fusion gene ', Leukemia, vol. 18, no. 5, pp. 1020-1021 . https://doi.org/10.1038/sj.leu.2403338

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adad26e9dcf31324330b425f7caeb5eb
https://hdl.handle.net/1871/26144

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