Phase 1, single‐dose escalating study of marzeptacog alfa (activated), a recombinant factor VIIa variant, in patients with severe hemophilia

Autor: R.A. Gruppo, D. Malan, J. Kapocsi, L. Nemes, C.R.M. Hay, L. Boggio, P. Chowdary, G. Tagariello, A. von Drygalski, F. Hua, M. Scaramozza, S. Arkin, C.R.J.R. Hermans, C. Claes, I. Hanes, I. Huyghe, C. Kantaridis, L.M. da Costa, M.‐N. Ndongo, W. Petit, E.M. Santagostino, A. Cannavo, M.R. Fasulo, M.E. Mancuso, A. Tosetto, G. Castaman, L. Candiotto, P. Radossi, E. Scarpa, M.P. Smith, A.E. Dick, R.A. Robson, D.S. Waaka, C.J. Wynne, Z.E. Punt, K.R. Kavakli, C. Balkan, M. Duyu, S. Goksel, B. Karapinar, A.R. Ozyurek, G. Saydam, D.Y. Karapinar, M. Laffan, C.M. Millar, P.I. Suppiah, C.K. Rizleigh, G.P. Chowdary, J.S. Davies, E.L. Fosbury, S. Gill, G.N. Pike, J. Varghese Thachil, M. Recht, J. Deutsche, J. Taylor, K.A. Kalinyak, E.S. Mullins, J.S. Palumbo, C.T. Quinn, C. Tarango, S. Tarabar, P.A. Chandler, L. Deats, S.R. Deshpande, N.U. Epstein, A.G. Hansson, S.S. Pawlak, D. Rudin, L.A.J. Valentino, N.C. Kakodkar, M.L. Simpson, P.F. Fogarty, Tami L. Bach, Elaine Y. Chiang, J.W. Adamson, C.S. Glass, N. Sidhu, T.D. Tucker‐Greene

Publikováno v: Journal of Thrombosis and Haemostasis. 16:1984-1993

Essentials Marzeptacog alfa (activated) [MarzAA] is a novel variant of activated human factor VII. A phase 1 dose escalation trial of MarzAA was conducted in subjects with severe hemophilia. MarzAA was safe and tolerated at intravenous doses up to 30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603fd7ef6934d830d4cc2f0ffa2bda85
https://doi.org/10.1111/jth.14247

Murine Bone Marrow Cells Cultured Ex Vivo in the Presence of Multiple Cytokine Combinations Lose Radioprotective and Long-Term Engraftment Potential.

Autor: A. Von Drygalski, G. Alespeiti, L. Ren, J.W. Adamson

Publikováno v: Stem Cells & Development; Feb2004, Vol. 13 Issue 1, p101-111, 11p

Cellular origins of the fetal-haemoglobin-containing cells of normal adults

Autor: William G. Wood, J.W. Adamson, Christopher Bunch, David J. Weatherall

Publikováno v: Lancet (London, England). 1(8127)

The origin of the small population of adult red cells which contain Hb F (F-cells) has been studied in a clonal disorder of haemopoiesis, polycythaemia rubra vera (P.R.V.). In eleven patients who had not received cytotoxic therapy F-cells comprised l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae663adc92d5b9a2269033a578478c6
https://pubmed.ncbi.nlm.nih.gov/86885

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.