Zobrazeno 1 - 10
of 63
pro vyhledávání: '"J.V. Halliwell"'
Publikováno v:
Neuroscience Letters. 439:275-280
Many studies have used the channel blocker ZD 7288 to assess possible physiological and pathophysiological roles of hyperpolarization-activated cation currents ( I h ). In view of the known interplay between I h and other membrane conductances, the e
Autor:
J.V. Halliwell, Gareth Owen
Publikováno v:
European Journal of Neuroscience. 13:1767-1780
We have exploited the complementary arrangement of afferents in a coronal slice (300-400 microm) of the rat olfactory tubercle (OT) maintained in vitro to investigate transmission in two separate synaptic pathways. We recorded extracellular responses
Publikováno v:
Neuroscience Letters. 168:106-110
Synaptic transmission in the CA1 area of the hippocampal slice preparation in vitro was studied in bathing media containing different levels of divalent cations. Transmission was abolished by replacing the normal levels (2.5 mM) of Ca2+ with 3 mM Mg.
Autor:
J K Hadley, J.V. Halliwell
Publikováno v:
The European journal of neuroscience. 31(4)
The olfactory tubercle (OT) is found in the brains of mammals that are highly dependent on their sense of smell. Its human analogue is the poorly understood anterior perforated substance. Previous work on rat brain slices identified two types of fiel
Publikováno v:
Neuroscience letters. 425(1)
The piriform cortex (PC) is highly prone to epileptogenesis, particularly in immature animals, where decreased muscarinic modulation of PC intrinsic fibre excitatory neurotransmission is implicated as a likely cause. However, whether higher levels of
Autor:
J.V. Halliwell
Publisher Summary This chapter describes the physiological mechanisms in the hippocampus that are the targets for modulation and control by released acetylcholine (ACh). The electrophysiological processes that govern the excitability and firing patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a9d6dde1f6a91cc34855030049efe5
https://doi.org/10.1016/s0079-6123(08)60910-3
https://doi.org/10.1016/s0079-6123(08)60910-3
This chapter reviews properties and functions of endogenous ionic currents in hippocampal neurones. Currents considered are: Na currents INa(fast) and INa(slow); Ca currents; K currents--delayed rectifier IK(DR), transient IK(A), 'delay' current IK(D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a231c84f565bf7bee5a2355273d39a0
https://doi.org/10.1016/s0079-6123(08)61247-9
https://doi.org/10.1016/s0079-6123(08)61247-9
Autor:
J.V. Halliwell, C.N. Scholfield
Publikováno v:
Neuroscience Letters. 50:13-18
Inward membrane currents were recorded in tetrodotoxin-treated neurones of hippocampus and olfactory cortex in vitro after impalement with CsCl-containing microelectrodes to suppress potassium conductances. They were blocked by the Ca2+ -channel bloc
Publikováno v:
The Journal of Physiology. 341:655-670
We have used a rat brain-slice preparation to study the effects of some cholinomimetic and amino acid agonists and antagonists on the discharge frequency of neurones in the interpeduncular nucleus (i.p.n.), and on the response of these neurones to el
Autor:
J.V. Halliwell
Publikováno v:
Neuroscience Letters. 67:1-6
Intracellular recordings were made in slices of human neocortex that had been surgically excised from patients in order to remove deep lying brain tumours. In more than half the neurones studied under voltage-clamp (n = 9), a non-inactivating K + -cu