Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J.T. Lutgerink"'
Autor:
F.J. ten Vaarwerk, J.T. Lutgerink, J.C.S. Kleinjans, F. ten Hoor, A. Van Der Wurff, P.A.E.L. Schilderman
Publikováno v:
Food and Chemical Toxicology. 33:99-109
The effect of metabolic activation of the food additive 3-tert-butyl-4-hydroxyanisole (BHA) by prostaglandin H synthase on the gastro-intestinal cell proliferation was determined by studies of the nature and the time dependency of early lesions in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2a1e424a41f0ced8a6fee5234576e0
https://doi.org/10.1016/0278-6915(94)00125-8
https://doi.org/10.1016/0278-6915(94)00125-8
Autor:
Barbara Hoebee, J.T. Lutgerink, Hans F.C. Stavenuitez, J.Gerard Westra, E. Kriek, Ed de Graaf
Publikováno v:
Analytical Biochemistry. 201:127-133
A method for the sensitive detection of 8-hydroxyguanine residues in small amounts of DNA (0.2-2 micrograms) was developed. It comprises (i) the enzymatic hydrolysis of DNA to 2'-deoxyribonucleotide 3'-monophosphates, (ii) degradation of the bulk amo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ae3d6b52263ec4159034d0076dd99e
https://doi.org/10.1016/0003-2697(92)90184-9
https://doi.org/10.1016/0003-2697(92)90184-9
Publikováno v:
Nucleic Acids Research. 19:1745-1751
The existence of an unusual form of DNA modification in the bloodstream form of the African trypanosome Trypanosoma brucei has been inferred from partial resistance to cleavage of nuclear DNA with PstI and PvuII (Bernards et al, 1984; Pays et al, 198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d5e7b2dac86b12edcf9a9b24317944
https://doi.org/10.1093/nar/19.8.1745
https://doi.org/10.1093/nar/19.8.1745
Autor:
J.T. Lutgerink, J.G. Westra, E. Kriek, M.J. BIeeker, W.J. van Dijk, J. H. Van Boom, H. F. Brugghe, H.den van Elst, J. C. Klein, A.J.M. Bems, G.A.der van Marel
Publikováno v:
Nucleic Acids Research. 18:4131-4137
We developed a simian virus 40 based shuttle vector system to study the molecular consequences of distinct carcinogen-induced DNA lesions in human cells. To establish the mutagenicity of O4-ethylthymine adducts, oligonucleotides carrying a single O4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60895af60f5e4bd7822aebe815c0a399
https://doi.org/10.1093/nar/18.14.4131
https://doi.org/10.1093/nar/18.14.4131
Autor:
Michel J.X. Hillebrand, E. Kriek, N. van Zandwijk, J.T. Lutgerink, F.J. van Schooten, H.M. Jansen, F.E. van Leeuwen
Publikováno v:
ResearcherID
Carcinogenesis, 11(9), 1677-1681. Oxford University Press
Carcinogenesis, 11(9), 1677-1681. Oxford University Press
In an attempt to probe for polycyclic aromatic hydrocarbon (PAH)-DNA adducts in human subjects resulting from smoking (or other chronic environmental exposure), lung tissue and lung tumours were obtained from patients hospitalized for lung cancer. DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b15fb386b00014857a2de495590e75e
https://doi.org/10.1093/carcin/11.9.1677
https://doi.org/10.1093/carcin/11.9.1677
Autor:
R. van Grondelle, J.G. Westra, J. T. Bokma, Joh. Blok, L. P.A. van Houte, J.T. Lutgerink, J. Retèl
Publikováno v:
Carcinogenesis. 8:759-766
Calf thymus DNA was modified with 2-aminofluorene (AF) to different extents by treatment with N-hydroxy-2-aminofluorene. The AF-modified DNAs together with free AF, the AF-modified guanine (Gua-C8-AF) and the AF-modified deoxyguanosine (dGuo-C8-AF) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd33f8930bacf419c0d3e002742b61a
https://doi.org/10.1093/carcin/8.6.759
https://doi.org/10.1093/carcin/8.6.759
Publikováno v:
Carcinogenesis. 6:1501-1506
To examine the effects of aminofluorene-DNA adduct formation on the biological activity of DNA, single-stranded (ss) phi X174 DNA and phi X174 replicative form (RF) DNA were modified to different extents with 3H-labeled N-hydroxy-2-aminofluorene and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72717f8fc8183e9d9585ddb81e37f01
https://doi.org/10.1093/carcin/6.10.1501
https://doi.org/10.1093/carcin/6.10.1501
Publikováno v:
Carcinogenesis. 7:1359-1364
The major aminofluorene-DNA derivative, found in the liver of rats after administration of the hepatocarcinogen N-acetyl-2-aminofluorene and identified as N-(deoxyguanosin-8-yl)-2-aminofluorene (dGuo-C8-AF), was introduced in different amounts in sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a829c029ccfeb9b77ce4cc23dfcc1d1
https://doi.org/10.1093/carcin/7.8.1359
https://doi.org/10.1093/carcin/7.8.1359
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Akademický článek
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