Zobrazeno 1 - 10
of 48
pro vyhledávání: '"J.R. Reeves"'
Autor:
Jennifer Fraser, Timothy G. Cooke, P D Stanton, J.R. Reeves, D.M. Black, James J. Going, John M. S. Bartlett
Publikováno v:
British Journal of Cancer
To test the hypothesis that altered expression of BRCA1 protein may play an important role in sporadic breast cancer development, 50 randomly selected primary breast cancers (frozen sections, 5 years' median follow-up) were immunolabelled with two mo
Autor:
Elizabeth Mallon, P D Stanton, A.D. Watters, J.R. Reeves, John M. S. Bartlett, Brian Donald, Timothy G. Cooke, Jim Richmond, James J. Going, Rhona Ferrier
Publikováno v:
The Journal of Pathology. 195:422-428
The development of Herceptin (Trazumatab) makes testing for HER2 status important for choosing optimal therapy in breast cancer. This study addresses the precision, accuracy, and reproducibility of HER2 assays. HER2 was assessed retrospectively by im
Autor:
J.R. Reeves, Peter Stanton, S. Tovey, Caroline J Witton, John M. S. Bartlett, Timothy G. Cooke
Publikováno v:
Breast Cancer Research
Background We have shown previously that whereas overexpression of human epidermal growth factor receptor (HER)1, HER2 and HER3 is associated with poor prognosis in breast cancer, HER4 is associated with a good prognosis. Cell proliferation is a key
Autor:
John M. S. Bartlett, J.R. Reeves
In common with other tumor types, ovarian cancer is a genetic disease and work at the DNA or RNA level is crucial to gain an understanding of the genetic changes leading to tumor formation. Phenotypic change, however, is the result of loss or aberran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df55384eefc14bf810a5941df49e21b0
https://doi.org/10.1385/1-59259-071-3:471
https://doi.org/10.1385/1-59259-071-3:471
Publikováno v:
The Journal of pathology. 200(3)
EGFr/HER1 and c-erbB-2/HER2 expression are associated with poor prognosis in breast cancer. The type I receptor tyrosine kinase (RTK) family to which they belong has four members (HER1–4). In this study, expression of HER1–4 and oestrogen recepto
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 12
In recent years investigators have looked at the human epidermal growth factor receptor-2 (HER2), which is overexpressed in 20%-30% of breast cancer patients, with regard to its role as a prognostic and predictive factor. Although many studies have s
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 44(11)
The relationship between expression of the c-erbB-2 proto-oncogene and the biology of breast cancer has been investigated widely, most studies using immunohistochemistry in formalin-fixed, paraffin-embedded tissues. This technique is at best semiquan
Publikováno v:
European Journal of Cancer. 37:21-22
Autor:
P D Stanton, J.R. Reeves, B. Ozanne, Elizabeth Mallon, Timothy G. Cooke, W.D. George, D. Chong
Publikováno v:
European Journal of Cancer. 35:S89
Publikováno v:
European Journal of Cancer. 35:S203