Zobrazeno 1 - 10
of 381
pro vyhledávání: '"J.R. Pasqualini"'
Autor:
J.R. Pasqualini, G.S. Chetrite
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 98:12-17
Estradiol (E(2)) is an important risk factor in the development and progression of breast cancer. However, a "direct effect" of E(2) in breast cancerization has not yet been demonstrated. The estrogen receptor complex can mediate the activation of on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76403b2338b685587ac485fccaad2def
https://doi.org/10.1016/j.jsbmb.2005.10.001
https://doi.org/10.1016/j.jsbmb.2005.10.001
Autor:
J.R. Pasqualini
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 97:401-415
Human fetal and placental compartments have all the enzymatic systems necessary to produce steroid hormones. However, their activities are different and complementary: the fetus is very active in converting acetate into cholesterol, in transforming p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae87ef2e77f3fc5360a0aa1363d7fef
https://doi.org/10.1016/j.jsbmb.2005.08.004
https://doi.org/10.1016/j.jsbmb.2005.08.004
Autor:
Anthony W. Norman, J.R. Pasqualini
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. :1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27f132b6c9271e8db88435b5ea067e8a
https://doi.org/10.1016/j.jsbmb.2004.03.108
https://doi.org/10.1016/j.jsbmb.2004.03.108
Autor:
J.R. Pasqualini, G. Chetrite
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 78:21-24
The great majority of breast cancers are in their early stage hormone-dependent and it is well accepted that estradiol (E(2)) plays an important role in the genesis and evolution of this tumor. Human breast cancer tissues contain all the enzymes: est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f5497c63fbf0c85ff9e0c1264615423
https://doi.org/10.1016/s0960-0760(01)00080-2
https://doi.org/10.1016/s0960-0760(01)00080-2
Autor:
J.R Pasqualini, G.S Chetrite
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 69:287-292
Estrone sulfate (E 1 S) is concentrated in high levels in human breast cancer tissue. The values are particularly high in postmenopausal women and many times those circulating in the plasma. Also, the tissular concentration of this conjugate are sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b27a112eadb3b5d93e284025203d78
https://doi.org/10.1016/s0960-0760(99)00082-5
https://doi.org/10.1016/s0960-0760(99)00082-5
Publikováno v:
International Journal of Cancer. 70:639-643
In the present studies, the concentrations (mammary tissue and plasma) of estrone (E1), estradiol (E2) and their sulfates (E1S and E2S), as well as the sulfatase and aromatase activities, were evaluated in patients with breast fibroadenomas. Comparat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c95f84f004d73af0ba44da77513e3335
https://doi.org/10.1002/(sici)1097-0215(19970317)70:6<639::aid-ijc2>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19970317)70:6<639::aid-ijc2>3.0.co
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 46:17-23
In the present studies the action of Danazol on the conversion of estrone sulfate (E 1 S) to estradiol (E 2 ) as well as on the sulfatase activity in the MCF-7 and T-47D, hormone-dependent, and MDA-MB-231, hormone-independent, mammary cancer cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661e54212ecdd8c62421e2c9f47abfcc
https://doi.org/10.1016/0960-0760(93)90204-a
https://doi.org/10.1016/0960-0760(93)90204-a
Autor:
P. Bertrand-Mercat, J.R. Pasqualini
Publikováno v:
Life Sciences. 48:2081-2087
The effect of the antiestrogen 4-hydroxytamoxifen on the estradiol-stimulated acetylation of nuclear high mobility group (HMG) proteins was studied in the uterus of newborn (3-day-old) guinea-pig. 4-Hydroxytamoxifen (10−6 M) selectively inhibits th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b6dc97e2fce2ce29d46f52e4942021
https://doi.org/10.1016/0024-3205(91)90165-8
https://doi.org/10.1016/0024-3205(91)90165-8
Autor:
J.R. Pasqualini, C. Gelly
Publikováno v:
Cancer Letters. 50:133-139
The biological response on proliferation and progesterone receptor (PR) of the anti-estrogen ICI 164,384 [N-n-butyl-N-methyl-11-(3,17β-dihydroxyestra-1,3,5(10-trien-7α-yl))-undecanamide] was studied in different mammary cancer cell lines. In the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c4fbc4a464473d82c5e184df862180
https://doi.org/10.1016/0304-3835(90)90243-q
https://doi.org/10.1016/0304-3835(90)90243-q
Autor:
J.R Pasqualini
Publikováno v:
Maturitas. 46
There is substantial evidence that mammary cancer tissue contains all the enzymes responsible for the local biosynthesis of estradiol (E2) from circulating precursors. Two principal pathways are implicated in the final steps of E2 formation in breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76c842042ff539f054e6b20b4c49edb
https://pubmed.ncbi.nlm.nih.gov/14670645
https://pubmed.ncbi.nlm.nih.gov/14670645