Výsledky vyhledávání - "J.R. Hawkins"

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Developmental aspects of androgen action

Autor: Syed Faisal Ahmed, J.R. Hawkins, Howard Martin, L. Dovey, Nigel P. Mongan, Han N. Lim, Ieuan A. Hughes

Publikováno v: Molecular and Cellular Endocrinology. 185:33-41

The formation of a testis from the indifferent gonad is the prelude to sequential steps in male sex differentiation orchestrated by time-dependent androgen biosynthesis and action. Information about the cellular and molecular mechanisms of androgen a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e0bebe522f1234f75443d2e191199b
https://doi.org/10.1016/s0303-7207(01)00622-0

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Phenotypic Features, Androgen Receptor Binding, and Mutational Analysis in 278 Clinical Cases Reported as Androgen Insensitivity Syndrome1

Autor: A Cheng, Ieuan A. Hughes, L. Dovey, N. Shimura, Jennifer E. Rowland, J.R. Hawkins, Howard Martin, Syed Faisal Ahmed, A. D. Tait

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 85:658-665

Androgen insensitivity syndrome (AIS) is the most common single entity that results in male under-masculinization, but large cohort studies of AIS have rarely been performed. Over the last decade, nationwide cooperation between pediatric endocrinolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c2c328d996b34c13b4d9a7ebe7b81c81
https://doi.org/10.1210/jcem.85.2.6337

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Candidate genes in complete and partial XY sex reversal: Mutation analysis of SRY, SRY-related genes and FTZ-F1

Autor: S.H. Freestone, D. Romero, Han N. Lim, J.R. Hawkins, Ieuan A. Hughes, C Kwok

Publikováno v: Molecular and Cellular Endocrinology. 140:51-58

The sexual phenotype is established in three steps: (1) the sex chromosome constitution; (2) the differentiation of the gonads; and (3) the response of the internal and external genitalia to the hormones produced by the differentiated gonads. Errors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9510273e7313433f83425e9ce88ef299
https://doi.org/10.1016/s0303-7207(98)00029-x

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Contents, Vol. 38, 1992

Autor: Masao Ota, Fausto Zuccato, J. Smitz, P. Rochiccioli, F. Alexandre, T. Torresani, M.T. Tauber, Hideo Sasaki, H. Loeb, H.R. Davies, Massimo Licini, Noriko Ohara, Fernández Martín, R.V.G. García-Mayor, Akira Sekikawa, Ichiro Komiya, Anna Rosa Bussi, Andrade Olivié, Fabio Legati, B. Rogé, Hirofumi Fukushima, P.C. Sizonenko, Johan Auwerx, Ivar K. Rossavik, Maurizio Schettino, Gorm Greisen, I. Dab, G.E. Theintz, J.R. Hawkins, J. De Schepper, E. Flutters, Hiromi Ootsuka, Nobuyuki Takasu, Milo Zachmann, S. Hachimi-Idrissi, M.N. Patterson, C. Páramo, J.-E. Toublanc, S.A. Chalew, D.M. Williams, Afonso Lopes, Takashi Yamada, A. Kowarski, Pankaja S. Venkataraman, Michael R. Waterman, J.C. Galofré, J.A. Batch, Mark A. Brandenburg, William B. Wehrenberg, I.A. Hughes, B.D. Brown, D.J. Hill, B. Sopeña, Diane S. Keeney, B.A.J. Evans, Makoto Tominaga, Z. Zadik, Andrea Giustina

Publikováno v: Hormone Research. 38:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f52033611c3f99a8f69051f465e969bf
https://doi.org/10.1159/000182539

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Longer polyglutamine tracts in the androgen receptor are associated with moderate to severe undermasculinized genitalia in XY males

Autor: Richard Nixon, Ieuan A. Hughes, Han N. Lim, Simon McBride, H. Chen, J.R. Hawkins, Alison M. Dunning

Publikováno v: Human molecular genetics. 9(5)

The androgen receptor (AR) is essential to the normal development of the male internal and external genitalia. Consequently, impairment of AR function can result in undermasculinized genitalia that vary from a completely female appearance to isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb0a8bb91cb37849bc6ba95fa5aa2a1
https://pubmed.ncbi.nlm.nih.gov/10749991

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Sexual dimorphism in the neonatal gonad

Autor: N Coleman, A Cheng, Han N. Lim, J.R. Hawkins, K L Ng, S Faisal Ahmed, Ieuan A. Hughes

Publikováno v: Acta paediatrica (Oslo, Norway : 1992). Supplement. 88(428)

The neonatal gonad has two distinct forms (i.e., is sexually dimorphic), as judged by morphological and endocrine characteristics. The dimorphic process begins early in embryogenesis. It is well established by the time of birth, by which time the gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f6cbfc557dbeb07be834a8cfc9a526
https://pubmed.ncbi.nlm.nih.gov/10102048

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Calbindin and parvalbumin are early markers of non-mitotically regenerating hair cells in the bullfrog vestibular otolith organs

Autor: Richard A. Baird, N. R. Schuff, J.R Hawkins, Peter S. Steyger, Melvin D. Burton

Publikováno v: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 15(4-5)

Earlier studies have demonstrated hair cell regeneration in the absence of cell proliferation, and suggested that supporting cells could phenotypically convert into hair cells following hair cell loss. Because calcium-binding proteins are involved in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad08263b265ce7e840ffaa0aa1ec4b8
https://pubmed.ncbi.nlm.nih.gov/9263023

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