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Akademický článek

The Total Thrombus Formation (T-TAS) platelet (PL) assay, a novel test that evaluates whole blood platelet thrombus formation under physiological conditions

Autor: K.L. Zheng, H. Wallen, D. Aradi, T.C. Godschalk, C.M. Hackeng, J.R. Dahlen, J.M. Ten Berg

Publikováno v: Platelets, Vol 33, Iss 2, Pp 273-277 (2022)

Dual antiplatelet therapy (DAPT, aspirin, and a P2Y12 inhibitor) reduces thrombotic events in patients with coronary artery disease (CAD). The T-TAS PL assay uses arterial shear flow over collagen surface, better mimicking in vivo conditions compared

Externí odkaz: https://doaj.org/article/4c646e79b5ef44f7ab5e8d7c82c0aa97

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Low energy cyclotron production and chemical separation of 'no carrier added' iodine-124 from a reusable, enriched tellurium-124 dioxide/aluminum oxide solid solution target

Autor: J. Koziorowski, Julius Balatoni, Y. Sheh, C. Lom, J.R. Dahl, Ronald D. Finn

Publikováno v: Radiochimica Acta. 88:169-174

Iodine-124 is a radionuclide with a 4.18 day half-life which decays by positron emission(23.3%) and electron capture (76.7%). Details on the preparation of this radionuclide via the 124Te(p,n)124I nuclear reaction are described. A reusable target uni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f7b755266736cb1e213f79f4b6bfa9d
https://doi.org/10.1524/ract.2000.88.3-4.169

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Cyclotron production and potential clinical application of Iodine-124 labeled radiotracers

Autor: J.R. Dahl, H. R. Adams, Julius Balatoni, Ronald D. Finn, K. Pentlow, Y. Sheh, S. M. Larson, P. Kothari, W. Eckelman, C. Lom, P. Plascjak

Publikováno v: AIP Conference Proceedings.

Positron emission tomography (PET) is a dynamic molecular imaging technique applicable to clinical research, drug development as well as clinical diagnoses. The potential for PET is derived from specificity of the radiotracers and radioligands that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ae2589f838e028edec46ff4ed930589
https://doi.org/10.1063/1.1395436

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Consequences of electroplated targets on radiopharmaceutical preparations

Autor: A. Knott, Steven M. Larson, Y. Sheh, A.S. Gelbard, J.R. Dahl, S. Tirelli, Ronald D. Finn

Publikováno v: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. :1284-1286

The staff of the cyclotron facility at Memorial Sloan-Kettering Cancer Center is involved in a comprehensive radionuclide preparation program which culminates with the formulation of numerous requested short-lived, positron-emitting radiopharmaceutic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca389dcfa61ab2352ca098d59722750b
https://doi.org/10.1016/0168-583x(91)95152-4

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Akademický článek

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Synthesis and purification of sodium [11C]benzoate for physiological and metabolic studies: evaluation in a tumor-bearing dog

Autor: P.B. Zanzonico, R. Lee, M.B. Winstead, R.E. Bigler, J.K. Jacobsen, Robert E. Reiman, B. Schmall, J.R. Dahl, P.S. Conti

Publikováno v: International Journal of Nuclear Medicine and Biology. 11:179-183

Sodium benzoate labeled with the cyclotron produced, positron emitting radioisotope 11C ( t 1 2 = 20.4 min ) has been investigated as a potential agent for renal and tumor visualization using γ-scintigraphy. Sodium [11]benzoate was prepared by the G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7aff4ec5af3822e1eb7165fa43a378a
https://doi.org/10.1016/0047-0740(84)90058-5

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The use of a compact, multi-particle cyclotron for the production of 52Fe, 67Ga, 111In and 123I for medical purposes

Autor: J.R. Dahl, Roy S. Tilbury

Publikováno v: The International Journal of Applied Radiation and Isotopes. 23:431-437

Methods of production of 52 Fe, 67 Ga, 111 In and 123 I using a small medical cyclotron are described and discussed. The methods of preparing targets by electroplating are described as well as the design and operation of the internal target probe. Yi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225432f6e52d204c82061f6ea8092c70
https://doi.org/10.1016/0020-708x(72)90110-x

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