Zobrazeno 1 - 10
of 29
pro vyhledávání: '"J.P. Swerts"'
Autor:
M.J. Guinaudy, Cathy Soula, Y Sagot, A.M. Duprat, P Ferrara, J.P. Swerts, Jean-Claude Guillemot, Philippe Cochard
Publikováno v:
Journal of Biological Chemistry. 267:10596-10600
In adult mammals, injured axons regrow over long distances in peripheral nerves but fail to do so in the central nervous system. Analysis of molecular components of tissue environments that allow axonal regrowth revealed a dramatic increase in the le
Publikováno v:
Brain research. 543(1)
We have used the recently developed cryoculture bioassay (Carbonetto et al., J. Neurosci., 7 (1987) 610-620) to document changes during development of CNS tissular ability to support nerve fiber growth. Neuronal attachment and neurite outgrowth of pu
Autor:
Alain Foucault, Anne Guyon, Bernard P. Roques, F. Guyon, Jean-Charles Schwartz, J.P. Swerts, Rémy Perdrisot
Publikováno v:
Life Sciences. 25:1605-1611
The degradation of the Met-enkephalin by peptidases present in striatum extracts was followed by a new H.P.L.C. method, based on ligand exchange chromatography. An aminopeptidase activity is present in both the soluble and the particulate fractions o
Autor:
Bernard Malfroy, Jacques Barbet, Jean-Charles Schwartz, J.P. Swerts, Bernard P. Roques, Anne Guyon
Publikováno v:
Biochemical and Biophysical Research Communications. 88:919-926
The breakdown of the Tyr-Gly bond of enkephalins by aminopeptidases from mouse striatum can be studied by following the disappearance of energy transfer between the tyrosine residue and the dimethylaminonaphtalene sulfonyl group (DNS) in the biologic
Publikováno v:
Neuroscience Letters. 11:329-334
The distribution of a high affinity enkephalin-dipeptidylcarboxypeptidase between regions of mouse brain is markedly heterogenous and parallels that of opiate receptors. Furthermore intrastriatal administration of kainic acid as well as interruption
Autor:
Bernard P. Roques, Jean-Charles Schwartz, Marie-Claude Fournie-Zaluski, J.P. Swerts, Gilles Gacel, Rémi Perdrisot, C. Llorens
Publikováno v:
Biochemical and biophysical research communications. 96(4)
The inhibitory potency (IC 50 ) of a variety of dipeptides regarding enkephalinase (enkephalin carboxydipeptidase) activity from mouse striatum indicates that the substrate specificity of this enzyme can be clearly distinguished from that of other me
Publikováno v:
Nature. 276(5687)
CONSIDERABLE evidence now exists to suggest that the endogenous opioid pentapeptides Met-enkephalin (Tyr-Gly-Gly-Phe-Met) and Leu-enkephalin (Tyr-Gly-Gly-Phe-Leu) function as neurotransmitters in the central nervous system. A correlate of this hypoth
Autor:
Marie-Claude Fournie-Zaluski, Jean-Charles Schwartz, Bernard Senault, E. Fellion, Jeanne-Marie Lecomte, J.P. Swerts, Gilles Gacel, Bernard P. Roques, Bernard Malfroy
Publikováno v:
Life sciences. 24(8)
In order to explore the role of the additional Arg or Tyr residue in the activity of Arg-Methionine-enkephalin (Arg-Met-E) and Tyr-Met-E, a series of analog were prepared and their biological activities in the inhibition of 3 H-Leu-E binding to mouse
Publikováno v:
European journal of pharmacology. 57(2-3)
Autor:
B.P. Roques, G. Gacel, Marie-Claude Fournie-Zaluski, Bernard Malfroy, B. Senault, J.-C. Schwartz, J.M. Lecomte, J.P. Swerts
Publikováno v:
Biochemical and biophysical research communications. 83(1)
Fluorescent dansylated derivatives of enkephalins were prepared, with the dansyl group either at the N- or C-terminal part of methionine-enkephalin (Met-E) or its peptidase-resistant analogue D-Ala2-Met-E. An energy transfer, from the Tyr to the dans