Zobrazeno 1 - 10
of 133
pro vyhledávání: '"J.P. Franke"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis, 48(1), 158-170. ELSEVIER SCIENCE BV
Solid phase extraction (SPE) is a widely used method for sample cleanup and sample concentration in bioanalytical sample preparation. A few methods to model the retention behaviour on SPE cartridges have been described previously but they are either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f090b486204caeb450174e69ba5f4d
https://research.rug.nl/en/publications/fbbb618d-02db-43b0-818f-28e8aef8512e
https://research.rug.nl/en/publications/fbbb618d-02db-43b0-818f-28e8aef8512e
Publikováno v:
Journal of Proteome Research, 5(5), 1186-1194. NLM (Medline)
An automated inhibitor affinity extraction method for the activity-based enrichment of matrix metalloproteases (MMPs) is presented. Samples containing purified MMP-12 were first extracted at different flow rates in a syringe pump setup, using cartrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af30152c8f831aee99fb21f60859b273
https://doi.org/10.1021/pr050483b
https://doi.org/10.1021/pr050483b
Publikováno v:
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 829(1-2):1-25
Receptor-ligand interactions play a crucial role in biological systems and their measurement forms an important part of modem pharmaceutical development. Numerous assay formats are available that can be used to screen and quantify receptor ligands. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba0c1f728d0d123b00fb9f1d721b2db9
https://doi.org/10.1016/j.jchromb.2005.10.002
https://doi.org/10.1016/j.jchromb.2005.10.002
Autor:
J.P. Franke, Rainer Bischoff, Donald R. A. Uges, Marieke P.H. Kroeze, Katharina Krämer, Lutea A.A. de Jong
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis, 39(5), 964-971. ELSEVIER SCIENCE BV
This article describes the development and validation of a radioreceptor assay for the determination of morphine and morphine-6-beta-glucuronide (M6G) in serum. The assay is based on competitive inhibition of the mu-opioid-selective radiolabeled liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbef1f5e45f50fabea1028b74c80764
https://doi.org/10.1016/j.jpba.2005.04.049
https://doi.org/10.1016/j.jpba.2005.04.049
Publikováno v:
Protein Expression and Purification, 33(2), 176-184
The human dopamine D2S receptor was expressed in the methylotrophic yeast Pichia pastoris, where the receptor with a molecular mass of approximately 40 kDa exhibited specific and saturable binding properties. The dopamine antagonist [H-3]spiperone sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e868531dc86ddf8876752172a8c627
https://doi.org/10.1016/j.pep.2003.08.018
https://doi.org/10.1016/j.pep.2003.08.018
Publikováno v:
Chromatographia, 57(3-4), 221-225
Solid-phase extraction (SPE) was combined with thermal desorption (TD) and gas chromatographic (GC) analysis to determine drugs in urine. The extraction was performed inside a fritted GC liner using about 5 mg TENAX that was inserted into the liner o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0fd99a2e36c8b668908f800e731a462
https://research.rug.nl/en/publications/f79ff57d-1b41-4930-89e5-e0681123a87c
https://research.rug.nl/en/publications/f79ff57d-1b41-4930-89e5-e0681123a87c
Publikováno v:
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 766(1), 37-45. ELSEVIER SCIENCE BV
Solid-phase extraction-pipette tips (SPE-PTs) were used for micro solid-phase extraction of lidocaine and diazepam from plasma. Off-line extraction was followed by on-line desorption. On-line desorption was carried out by direct coupling of the SPE-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680cfca22e138beb4cccb857c7287c63
https://doi.org/10.1016/s0378-4347(01)00431-5
https://doi.org/10.1016/s0378-4347(01)00431-5
Publikováno v:
Journal of Analytical Toxicology, 26(1), 48-51. Oxford University Press
Broad-spectrum drug screening is frequently applied inforensic and clinical toxicology, drugs and driving and doping,for example. It requires that all toxicologically relevant sub-stances be isolated, detected, and identified, regardless theirstructu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc8a3e784d2c3e7be9fc11e97f4ab26
https://research.rug.nl/en/publications/a0d44209-bd33-4f20-bd66-9e4627cccf29
https://research.rug.nl/en/publications/a0d44209-bd33-4f20-bd66-9e4627cccf29
Autor:
Dirk Sleijfer, Donald R. A. Uges, Tom Gelevert, Jaurik A. Gietema, Jürgen Messerschmidt, MT Meinardi, F. Alt, J.P. Franke
Publikováno v:
Therapeutic Drug Monitoring. 23:169-173
Patients cured of metastatic testicular cancer with cisplatin chemotherapy may suffer late adverse effects even after 20 years. The cause of these late adverse effects has not been elucidated yet. One cause might be prolonged tissue retention of plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c892e933d2b2305401faf8ea3701ee2
https://doi.org/10.1097/00007691-200104000-00013
https://doi.org/10.1097/00007691-200104000-00013
Publikováno v:
Journal of Analytical Toxicology, 24(2), 97-101. Oxford University Press
Broad-spectrum drug screening requires that all relevant substances be isolated, detected, and identified, regardless of their structure and/or polarity. To this end, systematic solid-phase extraction (SPE) approaches for drug isolation from biologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db72129504fc05dfbea9fba8de8a8b4
https://doi.org/10.1093/jat/24.2.97
https://doi.org/10.1093/jat/24.2.97