Zobrazeno 1 - 10
of 277
pro vyhledávání: '"J.P. Franke"'
Autor:
Zhao, Xianxian1,2 (AUTHOR) 18486302954@163.com, Wang, Yizhou1,2 (AUTHOR) wangzl@gzu.edu.cn, Wang, Zhenlu1 (AUTHOR) 18786109114@163.com, Luo, Tianma1,2 (AUTHOR) shaojian5098@163.com, Huang, Jun3 (AUTHOR) 13697335706@163.com, Shao, Jian1 (AUTHOR)
Publikováno v:
Animals (2076-2615). Oct2024, Vol. 14 Issue 20, p3005. 14p.
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis, 48(1), 158-170. ELSEVIER SCIENCE BV
Solid phase extraction (SPE) is a widely used method for sample cleanup and sample concentration in bioanalytical sample preparation. A few methods to model the retention behaviour on SPE cartridges have been described previously but they are either
Publikováno v:
Journal of Proteome Research, 5(5), 1186-1194. NLM (Medline)
An automated inhibitor affinity extraction method for the activity-based enrichment of matrix metalloproteases (MMPs) is presented. Samples containing purified MMP-12 were first extracted at different flow rates in a syringe pump setup, using cartrid
Publikováno v:
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 829(1-2):1-25
Receptor-ligand interactions play a crucial role in biological systems and their measurement forms an important part of modem pharmaceutical development. Numerous assay formats are available that can be used to screen and quantify receptor ligands. I
Autor:
J.P. Franke, Rainer Bischoff, Donald R. A. Uges, Marieke P.H. Kroeze, Katharina Krämer, Lutea A.A. de Jong
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis, 39(5), 964-971. ELSEVIER SCIENCE BV
This article describes the development and validation of a radioreceptor assay for the determination of morphine and morphine-6-beta-glucuronide (M6G) in serum. The assay is based on competitive inhibition of the mu-opioid-selective radiolabeled liga
Publikováno v:
Protein Expression and Purification, 33(2), 176-184
The human dopamine D2S receptor was expressed in the methylotrophic yeast Pichia pastoris, where the receptor with a molecular mass of approximately 40 kDa exhibited specific and saturable binding properties. The dopamine antagonist [H-3]spiperone sh
Publikováno v:
Chromatographia, 57(3-4), 221-225
Solid-phase extraction (SPE) was combined with thermal desorption (TD) and gas chromatographic (GC) analysis to determine drugs in urine. The extraction was performed inside a fritted GC liner using about 5 mg TENAX that was inserted into the liner o
Publikováno v:
Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 766(1), 37-45. ELSEVIER SCIENCE BV
Solid-phase extraction-pipette tips (SPE-PTs) were used for micro solid-phase extraction of lidocaine and diazepam from plasma. Off-line extraction was followed by on-line desorption. On-line desorption was carried out by direct coupling of the SPE-P
Publikováno v:
Journal of Analytical Toxicology, 26(1), 48-51. Oxford University Press
Broad-spectrum drug screening is frequently applied inforensic and clinical toxicology, drugs and driving and doping,for example. It requires that all toxicologically relevant sub-stances be isolated, detected, and identified, regardless theirstructu
Autor:
Dirk Sleijfer, Donald R. A. Uges, Tom Gelevert, Jaurik A. Gietema, Jürgen Messerschmidt, MT Meinardi, F. Alt, J.P. Franke
Publikováno v:
Therapeutic Drug Monitoring. 23:169-173
Patients cured of metastatic testicular cancer with cisplatin chemotherapy may suffer late adverse effects even after 20 years. The cause of these late adverse effects has not been elucidated yet. One cause might be prolonged tissue retention of plat