Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J.Mark Farrant"'
Publikováno v:
Gastroenterology. 108:865-869
Background/Aims: The diagnosis of cholangiocarcinoma in primary sclerosing cholangitis (PSC), even with the use of current imaging techniques and brush cytology, is difficult and particularly important in patients being assessed for liver transplanta
Autor:
Giorgina Mieli-Vergani, Adrian L. W. F. Eddleston, Peter T. Donaldson, Derek G. Doherty, Ann Duthie, J.Mark Farrant, James A. Underhill, Ian G. McFarlane, Alex P. Mowat, Philip J. Johnson, Roger Williams
Publikováno v:
Hepatology. 19:609-615
Susceptibility to autoimmune hepatitis in white patients is associated with the human leukocyte antigen class II antigens DR3 and DR4. To analyze the molecular basis of these associations, we used oligonucleotide probes to determine the DRB, DQA and
Autor:
Roger Williams, Ken I. Welsh, Robert Vaughan, Adrian L. W. F. Eddleston, Peter T. Donaldson, Derek G. Doherty, Karen M. Hayllar, J.Mark Farrant
Publikováno v:
Hepatology (Baltimore, Md.). 16(2)
Previous studies based on serological HLA phenotyping have implicated genes in the HLA class II region in susceptibility to and protection from primary sclerosing cholangitis. In a recent report, the HLA DRw52a antigen was present in all 29 patients
Autor:
J.Mark Farrant, David Westaby, Mark L. Wilkinson, Karen M. Hayllar, Roger Williams, John Karani, Bernard Portmann
Publikováno v:
Gastroenterology. 100(6)
The clinical features at the time of presentation and the outcome in 126 patients with primary sclerosing cholangitis were studied to clarify the natural history and prognosis in symptomatic and asymptomatic individuals. The median age of the patient
Autor:
J.Mark Farrant, G Senaldi, Roger Williams, Graeme J.M. Alexander, Diego Vergani, Peter T. Donaldson, Silvio Magrin
Publikováno v:
Gastroenterology. 97(6)
Recent evidence, including the presence of circulating immune complexes, suggests that abnormalities of humoral immunity may be important in the pathogenesis of primary sclerosing cholangitis. The aim of the present study was to determine whether act