Phenotypic profiling of CD34+ cells by advanced flow cytometry improves diagnosis of juvenile myelomonocytic leukemia

Autor: Cristina Bugarin, Laura Antolini, Chiara Buracchi, Sergio Matarraz, Tiziana Angela Coliva, Vincent H. van der Velden, Tomasz Szczepanski, Elaine Sobral da Costa, Alita van der Sluijs, Michaela Novakova, Ester Mejstrikova, Stefan Nierkens, Fabiana Vieira de Mello, Paula Fernandez, Carmen Aanei, Łukasz Sędek, Luisa Strocchio, Riccardo Masetti, Laura Sainati, Jan Philippé, Maria Grazia Valsecchi, Franco Locatelli, Jacques J.M. van Dongen, Andrea Biondi, Alberto Orfao, Giuseppe Gaipa

Publikováno v: Haematologica, Vol 109, Iss 2 (2023)

Diagnostic criteria for juvenile myelomonocytic leukemia (JMML) are currently well defined, however in some patients diagnosis still remains a challenge. Flow cytometry is a well established tool for diagnosis and follow-up of hematological malignanc

Externí odkaz: https://doaj.org/article/3abdb5e2d8864a9e90c339f16117bbbf

Experience With IVDR Implementation in Three Diagnostic Laboratories: Messages to EU Health Institutions, Diagnostic Healthcare Payers, and Authorities

Autor: Bart R. Lubbers, Isabel Dombrink, Tomas Kalina, Mattias Hofmans, Morten S. Bruun, Simon J. Stanworth, Marie C. Béné, Konstanze Döhner, Monika Brüggemann, Elizabeth Macintyre, Jacques J.M. van Dongen

Publikováno v: HemaSphere, Vol 7, Iss 4, p e865 (2023)

Externí odkaz: https://doaj.org/article/69d8edeb5ddf4d78b50d553c9477a008

Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID

Autor: Laura Garcia-Perez, Marja van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, Michael Rothe, Dagmar Berghuis, Chantal Lagresle-Peyrou, Marina Cavazzana, Fang Zhang, Adrian J. Thrasher, Daniela Salvatori, Pauline Meij, Anna Villa, Jacques J.M. Van Dongen, Jaap-Jan Zwaginga, Mirjam van der Burg, H. Bobby Gaspar, Arjan Lankester, Frank J.T. Staal, Karin Pike-Overzet

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 666-682 (2020)

Recombinase-activating gene-1 (RAG1)-deficient severe combined immunodeficiency (SCID) patients lack B and T lymphocytes due to the inability to rearrange immunoglobulin and T cell receptor genes. Gene therapy is an alternative for those RAG1-SCID pa

Externí odkaz: https://doaj.org/article/054d2c31c1974fd68ef81093f23e0c9c

Dissection of the Pre-Germinal Center B-Cell Maturation Pathway in Common Variable Immunodeficiency Based on Standardized Flow Cytometric EuroFlow Tools

Autor: Lucía del Pino-Molina, Eduardo López-Granados, Quentin Lecrevisse, Juan Torres Canizales, Martín Pérez-Andrés, Elena Blanco, Marjolein Wentink, Carolien Bonroy, Jana Nechvatalova, Tomas Milota, Anne-Kathrin Kienzler, Jan Philippé, Ana E. Sousa, Mirjam van der Burg, Tomas Kalina, Jacques J.M. van Dongen, Alberto Orfao

Publikováno v: Frontiers in Immunology, Vol 11 (2021)

IntroductionCommon Variable Immunodeficiency (CVID) is characterized by defective antibody production and hypogammaglobulinemia. Flow cytometry immunophenotyping of blood lymphocytes has become of great relevance for the diagnosis and classification

Externí odkaz: https://doaj.org/article/6ce62a42e8ed43f8beb66a248fe99179

The (cost-)effectiveness of combined lifestyle interventions for people with persistent low-back pain who are overweight or obese

Autor: J.C.J. Huijbers, P. Coenen, G.L.B. Burchell, M.W. Coppieters, I.H.M. Steenhuis, J.H. Van Dieën, B.W. Koes, D.H.R. Kempen, J.R. Anema, I. Kingma, L. Voogt, C.M. Williams, J.M. Van Dongen, H.P. Van der Ploeg, R.W.J.G. Ostelo, G.G.M. Scholten-Peeters

Publikováno v: Huijbers, J C J, Coenen, P, Burchell, G L B, Coppieters, M W, Steenhuis, I H M, van Dieën, J H, Koes, B W, Kempen, D H R, Anema, J R, Kingma, I, Voogt, L, Williams, C M, van Dongen, J M, van der Ploeg, H P, Ostelo, R W J G & Scholten-Peeters, G G M 2023, ' The (cost-)effectiveness of combined lifestyle interventions for people with persistent low-back pain who are overweight or obese : A systematic review ', Musculoskeletal Science and Practice, vol. 65, 102770 . https://doi.org/10.1016/j.msksp.2023.102770
Huijbers, J C J, Coenen, P, Burchell, G L B, Coppieters, M W, Steenhuis, I H M, Van Dieën, J H, Koes, B W, Kempen, D H R, Anema, J R, Kingma, I, Voogt, L, Williams, C M, Van Dongen, J M, Van der Ploeg, H P, Ostelo, R W J G & Scholten-Peeters, G G M 2023, ' The (cost-)effectiveness of combined lifestyle interventions for people with persistent low-back pain who are overweight or obese : A systematic review ', Musculoskeletal Science and Practice, vol. 65, 102770 . https://doi.org/10.1016/j.msksp.2023.102770
Musculoskeletal Science and Practice, 65:102770. Elsevier BV

Introduction: Lifestyle factors are expected to contribute to the persistence and burden of low-back pain (LBP). However, there are no systematic reviews on the (cost-)effectiveness of combined lifestyle interventions for overweight or obese people w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b771d47bb15749cecff623e5e60862
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