Zobrazeno 1 - 10
of 120
pro vyhledávání: '"J.M. Teijón"'
Publikováno v:
Pharmaceutical Research. 31:1264-1274
In vivo evaluation of tamoxifen (TMX)-loaded folate-targeted nanoparticles prepared from a mixture of disulphide bond reduced bovine serum albumin (BSA-SH) and alginate-cysteine (ALG-CYS) as targeted delivery systems of TMX to tumour tissues. TMX in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb5c2580627f0ef18424868c69889ea
https://doi.org/10.1007/s11095-013-1247-5
https://doi.org/10.1007/s11095-013-1247-5
Publikováno v:
International Journal of Pharmaceutics. 436:574-581
Tamoxifen (TMX) is the most common clinical choice for the treatment of advanced or metastatic estrogen-dependent breast cancer. However, research on new challenging therapies is necessary due to its undesirable side effects and the limitation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::008011495d092f7fc70eb58f4593e3ea
https://doi.org/10.1016/j.ijpharm.2012.07.045
https://doi.org/10.1016/j.ijpharm.2012.07.045
Autor:
María Dolores Blanco, J.M. Teijón, Rafael Lozano, I. Iglesias, A. Fenández, César Teijón, Marta Benito
Publikováno v:
Journal of Applied Polymer Science. 124:2987-2998
Mixtures of different bioerosionable polyesters were used to prepare microparticulated tamoxifen delivery systems to achieve anticancer effects in breast malignant cancer cells. Tamoxifen (TMX) was included into microspheres (MS) formulated via spray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42ba708c538365d294d6908c859eaee9
https://doi.org/10.1002/app.35327
https://doi.org/10.1002/app.35327
Publikováno v:
Journal of Inorganic Biochemistry. 99:2395-2402
The interaction between nickel and yeast hexokinase was studied. The binding of nickel showed a positive cooperativity, and saturation was not reached. The nickel binding induced modifications in the secondary structure of the protein; thus, a lost o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01862255cbabb645084809546bcfbdd4
https://doi.org/10.1016/j.jinorgbio.2005.09.007
https://doi.org/10.1016/j.jinorgbio.2005.09.007
Publikováno v:
Journal of Microencapsulation. 22:671-682
5-Fluorouracil (5-FU), a hydrosoluble anti-neoplastic drug, was encapsulated in microspheres of poly(D,L-lactide) (PLA) and poly(lactide-co-glycolide) (PLGA) polymers using the spray-drying technique, in order to obtain small size microspheres with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1476761635ba9b024ec690956a892e
https://doi.org/10.1080/02652040500161990
https://doi.org/10.1080/02652040500161990
Publikováno v:
Il Farmaco. 58:1187-1191
Chitosan beads loaded with bupivacaine (16+/-3 microg of drug per milligram of beads) were prepared by cross-linking with glutaraldehyde. In vitro drug release at pH and temperature conditions similar to those of the biological systems were studied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670fc21391cc0bf44d216c03049031d9
https://doi.org/10.1016/s0014-827x(03)00192-7
https://doi.org/10.1016/s0014-827x(03)00192-7
Publikováno v:
Journal of Applied Polymer Science. 86:327-334
Copolymeric hydrogels of poly(acrylamide-co-monomethyl itaconate) (A/MMI) crosslinked with N,N′-methylenbisacrylamide (NBA) were synthesized as devices for the controlled release of bupivacaine (Bp). Two compositions of the copolymer, 60A/40MMI and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bb9639a98f83db6fa5be558e376de0c
https://doi.org/10.1002/app.10962
https://doi.org/10.1002/app.10962
Publikováno v:
Polymer International. 50:822-827
The interaction between lead and yeast hexokinase has been studied. Lead provokes a large variation in the aggregation state of the protein, forming bigger structures of high molecular mass. This phenomenon is characterized by a small modification in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd12e67e0a5a4dc41d091b58ef48196
https://doi.org/10.1002/pi.703
https://doi.org/10.1002/pi.703
Publikováno v:
Journal of Pharmacy and Pharmacology. 52:1319-1325
Poly(2-hydroxyethyl methacrylate-co-acrylamide) hydrogels crosslinked with ethylen glycol dimethacrylate were used as devices for the in-vivo drug release of 5-fluorouracil (5-FU). Drug-loaded hydrogels were subcutaneously implanted in the back of Wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ccb697db8821e69106430e898ac830f
https://doi.org/10.1211/0022357001777469
https://doi.org/10.1211/0022357001777469
Publikováno v:
Journal of Protein Chemistry. 19:199-208
The aluminum and yeast hexokinase interaction was studied. Structural changes were correlated with variations in protein functionality. Results show two different behaviors: At low metal concentrations preferential adsorption of metal (and water excl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3daf625efb02bbdef02062e0020ac13
https://doi.org/10.1023/a:1007055719926
https://doi.org/10.1023/a:1007055719926