Zobrazeno 1 - 10
of 129
pro vyhledávání: '"J.M. Reiner"'
Publikováno v:
Journal of Lipid Research, Vol 15, Iss 4, Pp 326-331 (1974)
In this study, young growing swine were made hypercholesterolemic (∼300 mg/dl) by feeding milk and eggs for 7 wk. They were then divided into three groups (untreated, clofibrate-treated, and cholestyramine-treated), and the diet was continued for a
Externí odkaz:
https://doaj.org/article/85701461d6424dd0a29d0c8fba62b7e4
Publikováno v:
Journal of Lipid Research, Vol 13, Iss 5, Pp 600-615 (1972)
Studies of the interaction of cholesterol absorption, excretion, synthesis, and retention were carried out with growing swine through the application of sterol and isotopic balance procedures to a non-steady state situation. The animals were fed eith
Externí odkaz:
https://doaj.org/article/c0872e88e04646ea80521d66d6ca31d4
Publikováno v:
Experimental and Molecular Pathology. 24:360-374
The sine qua non of the lesion of atherosclerosis in man and experimental animals is excessive focal accumulation of modified smooth muscle cells in the intima of arteries. In advanced stages extensive necrosis with accumulation of lipid-rich debris
Publikováno v:
Experimental and Molecular Pathology. 34:191-201
Hybrid hares ( Lepus europaeus male x Lepus timidus female) were fed intermittently with a cholesterol-containing diet for 3 to 13 months. Their aortas were evaluated for extent of lesions, and for glucose-6-phosphate dehydrogenase (G-6-PD) isozyme p
Publikováno v:
Experimental and Molecular Pathology. 34:209-215
In this study fibroblast cultures from the skin of 11 hybrid female hares that were heterozygous for glucose-6-phosphate dehydrogenase (G-6-PD) were grown in a standard culture medium containing successively increasing concentrations of 25-hydroxycho
Publikováno v:
Atherosclerosis. 34:291-301
Summary In the abdominal aortas of young mash-fed swine, intimal cell masses (pads, cushions) are located predominantly away from blood vessel orifices. They are found scattered throughout the aorta but nevertheless have a definite pattern of distrib
Publikováno v:
Experimental and Molecular Pathology. 21:259-267
Previously we demonstrated in swine that a single ip injection of an aqueous extract of swine aortic tissue (containing less than a mg of protein) would inhibit entry of arterial smooth muscle cells into mitosis for at least 2 hr. In the current stud
Autor:
J.M. Reiner, Margaret Wiener
Publikováno v:
Mechanisms of Ageing and Development. 7:445-453
Dilution of tissue fractions from human placenta resulted in an increase in the specific activities of 3β- hydroxy -Δ 5 - steroid dehydrogenase and of 20α-hydroxysteroid dehydrogenase. The apparent K s and V max of 3β- hydroxy -Δ 5 - steroid deh
Publikováno v:
Experimental and Molecular Pathology. 31:318-332
The effects of cholestyramine on cholesterol balance parameters, bile acids and the enzyme activities of HMG-CoA reductase and cholesterol 7α-hydroxylase were studied in mash-fed young male Yorkshire swine. In addition, our previous results on chole
Publikováno v:
Experimental and Molecular Pathology. 24:244-260
The purpose of this study was to determine whether atherosclerotic lesions developing in young swine fed hypercholesterolemic (HC) diets were monoclonal or polyclonal in origin. The approach involved labeling arterial cells with tritiated thymidine p