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Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis

Autor: Andrew T. Chan, David Conen, Caroline Pot, Therese Lincke, Stephanie Meier, Chiara Zecca, Muhamed Barakovic, David Leppert, Johanna Oechtering, Sabine Schaedelin, Özgür Yaldizli, Oliver Findling, Jens Kuhle, Yvonne Naegelin, Stefanie Aeschbacher, Tobias Derfuss, Bettina Fischer-Barnicol, Aleksandra Maceski, Ingmar Heijnen, Tim Sinnecker, Patrice H. Lalive, Suvitha Subramaniam, Pascal Benkert, Heinz Wiendl, Riccardo Galbusera, Reza Rahmanzadeh, Giulio Disanto, Claudio Gobbi, Axel Regeniter, Lutz Achtnichts, J.M. Lieb, Ludwig Kappos, Klaus Berger, Annette Orleth, Jens Wuerfel, Stefanie Müller, Jochen Vehoff, Cristina Granziera

Publikováno v: Annals of Neurology
Oechtering, Johanna; Schaedelin, Sabine; Benkert, Pascal; Müller, Stefanie; Achtnichts, Lutz; Vehoff, Jochen; Disanto, Giulio; Findling, Oliver; Fischer-Barnicol, Bettina; Orleth, Annette; Chan, Andrew; Pot, Caroline; Barakovic, Muhamed; Rahmanzadeh, Reza; Galbusera, Riccardo; Heijnen, Ingmar; Lalive, Patrice H; Wuerfel, Jens; Subramaniam, Suvitha; Aeschbacher, Stefanie; ... (2021). Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis. Annals of neurology, 90(3), pp. 477-489. Wiley-Blackwell 10.1002/ana.26137
Annals of neurology, vol. 90, no. 3, pp. 477-489

We aimed to determine in relapsing multiple sclerosis (MS) whether intrathecal synthesis of immunoglobulin (Ig) M and IgG is associated with outcomes reflecting inflammatory activity and chronic worsening. We compared cerebrospinal fluid analysis, cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab1fe314388de122195b79e1794d174

Balkenfehlbildungen

Autor: J.M. Lieb, F J Ahlhelm

Publikováno v: Der Radiologe. 58:636-645

Clinical issue Agenesis of the corpus callosum is reported to have an incidence of about 1:4000 live births. In 30-45% of cases, genetic etiologies can be identified, e. g., 10% chromosomal anomalies and 20-35% genetic syndromes. Environmental factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74359ccba58f09b0e20b07b0f85c7deb
https://doi.org/10.1007/s00117-018-0388-2

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Postoperative Befunde an der Wirbelsäule

Autor: Stephan Ulmer, J.M. Lieb, Christoph Stippich, J. Kelm, F.J. Ahlhelm, K Shariat

Postoperative imaging after spinal surgery is usually performed to document the correct positioning of implants or to rule out complications if patients still suffer from pain after surgery. Depending on the question various imaging modalities can be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2fb6c84fdb4c87e97a2451d527fa72
http://doc.rero.ch/record/322170/files/117_2011_Article_2146.pdf