Zobrazeno 1 - 10
of 40
pro vyhledávání: '"J.M. Connellan"'
Publikováno v:
Thrombosis Research. 63:563-568
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d1349cacdaa78f396b805b53710ae9
https://doi.org/10.1016/0049-3848(91)90183-w
https://doi.org/10.1016/0049-3848(91)90183-w
Publikováno v:
British Journal of Haematology. 75:549-556
Summary. A monoclonal antibody (anti-Fn2) was prepared which was reactive with both plasma fibronectin and fibronectin located within the platelet alpha granule. Immunoblotting analysis, on thermolysin digestion fragments of fibronectin, identified t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73d1b5bd8a5776ed871a3e5f6601a04
https://doi.org/10.1111/j.1365-2141.1990.tb07797.x
https://doi.org/10.1111/j.1365-2141.1990.tb07797.x
Publikováno v:
Thrombosis research. 61(5-6)
Quinine, a drug known to induce immune mediated thrombocytopenia, has been postulated to mediate binding of drug dependent antibodies to a range of platelet membrane glycoproteins. Quinine may not act solely as a hapten however, as we have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca5fdf751a90a8465cf8f15b620f167
https://pubmed.ncbi.nlm.nih.gov/2028452
https://pubmed.ncbi.nlm.nih.gov/2028452
Publikováno v:
Thrombosis Research. 17:225-238
Collagen induces a coagulant activity in both PRP and washed platelets. The activity is inhibited by antifactor XI antibody (human). Platelet extracts partially corrected the clotting time of factor XI deficient plasma and were effected by antifactor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9addac4ed0ebd248ec50cb51c78cf66
https://doi.org/10.1016/0049-3848(80)90309-6
https://doi.org/10.1016/0049-3848(80)90309-6
Publikováno v:
Pathophysiology of Haemostasis and Thrombosis. 11:109-118
Platelets were labelled with surface-labelling agents which identified up to six platelet membrane proteins. Three of these labelled proteins were recognised by a specific anti-platelet membrane serum by immunoprecipitation. Affinity fractionation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85f9cdac92823cac06f5b92555c37fc
https://doi.org/10.1159/000214649
https://doi.org/10.1159/000214649
Publikováno v:
Thrombosis Research. 47:427-439
A murine monoclonal antibody (anti-C2G7), reactive with fibrinogen, was used to analyse the structure and function of the fibrinogen epitope C2G7. Anti-C2G7 was found to be reactive with fibrinogen but not with fibronectin, Factor VIII-von Willebrand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cece150e994be01b34a4e35e6d5b8f6
https://doi.org/10.1016/0049-3848(87)90458-0
https://doi.org/10.1016/0049-3848(87)90458-0
Publikováno v:
Pathophysiology of Haemostasis and Thrombosis. 6:41-52
Washed platelets were ruptured by freezing and thawing; a coagulant activity was released which would correct the clotting time of factor XI (FXI)-deficient plasma only in the presence of kaolin. Platelets from a FXI-deficient patient treated in a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a269ee1cef20bd5072f38fede907e47
https://doi.org/10.1159/000214164
https://doi.org/10.1159/000214164
Publikováno v:
VIth International Congress on Thrombosis and Haemostasis.
Platelets provide coagulant activities, other than the Phospholipid Platelet factor 3, which can be released from the platelet. In Platelet Poor Plasma, the initiation of the intrinsic pathway is proposed to proceed via factors Xll & XI as well as 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efbd307dab3442e138bb9d53de892b88
https://doi.org/10.1055/s-0039-1682669
https://doi.org/10.1055/s-0039-1682669
Publikováno v:
VIth International Congress on Thrombosis and Haemostasis.
Contact factors are known to be associated with platelets. There is evidence to suggest that F XI may mediate an enhancement of coagulant activity in response to collagen stimulation of platelets. The aim of this study was to further explore this rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd4deddeb25f1bd36ce5966fcdc31f8a
https://doi.org/10.1055/s-0039-1680644
https://doi.org/10.1055/s-0039-1680644
Autor:
P.A. Castaldi, J.M. Connellan
Publikováno v:
Thrombosis research. 7(5)
Factors XI and XIa have been purified by using affinity chromatography of plasma or contact product on heparin coupled to Sepharose. Further purification was achieved by chromatography on hydroxylapatite. Both forms of the protein co-chromatographed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d52ffa9286727a45d8040278ff8078
https://pubmed.ncbi.nlm.nih.gov/813327
https://pubmed.ncbi.nlm.nih.gov/813327