Zobrazeno 1 - 10
of 267
pro vyhledávání: '"J.M. Brogard"'
Publikováno v:
La Revue de Médecine Interne. 20:379s-383s
Resume La mise au point de therapeutiques antidiabetiques ayant des points d’impact complementaires, apparait desormais comme une necessite. En inhibant de facon reversible l’hydrolyse des disaccharides et les etapes ultimes de la digestion des p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f9ace7b9ce03878891f562fd80cf321
https://doi.org/10.1016/s0248-8663(99)80511-6
https://doi.org/10.1016/s0248-8663(99)80511-6
Publikováno v:
La Revue de Médecine Interne. 20:351s-359s
Resume L’anomalie fonctionnelle de la cellule β represente l’une des cibles therapeutiques majeures dans le traitement du diabete de type 2. Parmi les antidiabetiques oraux actuellement disponibles, seuls les sulfamides hypoglycemiants sont doue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0197f85a497ef25bb352c1b14097db8
https://doi.org/10.1016/s0248-8663(99)80508-6
https://doi.org/10.1016/s0248-8663(99)80508-6
Publikováno v:
La Revue de Médecine Interne. 20:371s-378s
The relief of insulin resistance is one of the two therapeutic targets of the treatment of type 2 diabetes. Insulin-sensitizers are therefore complemental with other oral diabetic drugs. The treatment of insulin resistance was for a long time limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::270066122df7842ca60405f0d08bedd5
https://doi.org/10.1016/s0248-8663(99)80510-4
https://doi.org/10.1016/s0248-8663(99)80510-4
Autor:
J.M. Brogard, Jean-Frédéric Westphal
Publikováno v:
Drugs. 57:81-91
Initial therapy of acute cholecystitis and cholangitis is directed towards general support of the patient, including fluid and electrolyte replacement, correction of metabolic imbalances and antibacterial therapy. Factors affecting the efficacy of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5157e87c2177d19219869a4989d160e4
https://doi.org/10.2165/00003495-199957010-00007
https://doi.org/10.2165/00003495-199957010-00007
Autor:
Jean-Frédéric Westphal, J.M. Brogard
Publikováno v:
Drug Safety. 17:47-73
Cirrhosis encompasses a range of pathophysiological changes that may alter drug disposition. Drugs that are dependent primarily on the liver for their systemic clearance are more likely to be subject to reduced elimination and subsequent accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da4203e990aa1366ea64c7713813299
https://doi.org/10.2165/00002018-199717010-00004
https://doi.org/10.2165/00002018-199717010-00004
Publikováno v:
La Revue de Médecine Interne. 16:20-30
Resume Deux mecanismes principaux, l'insulinoresistance peripherique et l'alteration de la secretion d'insuline participent conjointement, mais a des degres variables, a la genese du diabete non insulinodependant, maladie dont l'heterogeneite, longte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cdfd7e6d9b2b19240bf2797fa611b5c
https://doi.org/10.1016/0248-8663(96)80661-8
https://doi.org/10.1016/0248-8663(96)80661-8
Autor:
J.M. Brogard, Jean-Frédéric Westphal
Publikováno v:
Clinical Pharmacokinetics. 24:46-58
Liver disease may produce significant, albeit highly variable, effects on the pharmacokinetic behaviour of antibiotics in serum. Drug disposition may be altered through several pathophysiological mechanisms including reduced hepatobiliary clearance,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0909d91f359a8c14e99bf5c3cfd3800f
https://doi.org/10.2165/00003088-199324010-00004
https://doi.org/10.2165/00003088-199324010-00004
Autor:
J.F. Blicklé, J.M. Brogard
Publikováno v:
La Revue de Médecine Interne. 13:S285-S288
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6a798ae5bc6e7f4f5d20fe54739b02d
https://doi.org/10.1016/s0248-8663(05)80882-3
https://doi.org/10.1016/s0248-8663(05)80882-3
Publikováno v:
Médecine et Maladies Infectieuses. 21:685-693
Resume Chez l'homme, l'administration intraveineuse de 2 g de piperacilline a 6 sujets normaux a donne lieu a un passage moyen de 0,08 ± 0,03 % dans le liquide d'aspiration duodenale recueilli pendant les 4 heures succedant a l'injection. Chez 10 pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a1e909fe575d13ac8ba1251ae3cc9a3
https://doi.org/10.1016/s0399-077x(05)80234-3
https://doi.org/10.1016/s0399-077x(05)80234-3