Zobrazeno 1 - 10
of 15
pro vyhledávání: '"J.Gerald Brook"'
Publikováno v:
Pathophysiology. 4:235-240
Some cancer patients demonstrate low levels of plasma cholesterol. This has been explained as resulting from a defect in the cholesterol feedback control in tumor cells. The objective of this study was to determine the presence of a relationship betw
Publikováno v:
European Journal of Cardiovascular Prevention & Rehabilitation. 2:57-62
Increasing evidence suggests that oxidized low-density lipoprotein (LDL) is associated with the development of atherosclerosis in vivo. Because endothelial injury contributes to the development of the atherogenic , we investigated the efficacy of oxi
Publikováno v:
European journal of internal medicine. 19(3)
Background Mixed hyperlipidemia is a common disorder characterized by elevated VLDL and LDL levels. Patients with this syndrome usually are in need of combination therapy, comprising a fibric acid derivate with a statin drug in order to achieve LDL a
Autor:
Ruth Gershoni-Baruch, Ada Tamir, J.Gerald Brook, Ilana Kepten, Ilana Oren, Efrat Wolfovitz, Shai Linn
Publikováno v:
Atherosclerosis. 145(2)
Coronary artery disease is a polygenic disease whose phenotypic manifestation depends on the interaction of the genetic background with a number of environmental factors. Recently, the gene coding for the angiotensin-converting enzyme (ACE) has been
Publikováno v:
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies. 33(10)
Epidemiological evidence suggests that plasma high-density lipoprotein (HDL) is protective against coronary artery disease, whereas oxidatively modified low density lipoprotein is atherogenic. Human apolipoprotein A-I transgenic mice with overexpress
Publikováno v:
Metabolism: clinical and experimental. 41(3)
Under experimental conditions, oxidized low-density lipoprotein (Ox-LDL) may possess atherogenic properties, as is evidenced by its contribution to cholesterol accumulation in macrophages. LDL was oxidized in a cell-free system by predialysis of the
Publikováno v:
Metabolism: clinical and experimental. 40(3)
Both macrophages and platelets play an important role in atherogenesis. We studied the effect of conditioned medium obtained from human monocyte-derived macrophages on in vitro platelet aggregation. Incubation of macrophage-conditioned medium (MCM) w
Publikováno v:
Atherosclerosis. 65:207-214
Total cholesterol (TC) content of mouse peritoneal macrophages (MPM) increased when incubated with increasing concentrations of normal low density (N-LDL) or very low density (N-VLDL) lipoprotein. Incubation with increasing concentrations of normal h
Publikováno v:
Biochemical Medicine and Metabolic Biology. 41:117-124
The aims of our study were to assess the differences between plasma lipoproteins separated from five angiographically normal subjects and five patients with proven CHD. The patients with CHD had significantly higher levels of LDL-cholesterol and apo-
Publikováno v:
Biochemical Medicine. 30:253-260
High density lipoprotein (HDL) cholesterol, total cholesterol, and total triglyceride levels were assayed in the plasma of 42 octogenarians. No differences were found in the levels of HDL cholesterol and total triglycerides when comparing subjects wi