Výsledky vyhledávání - "J.G. Wolbers"

Damage to tumour and brain by interstitial photodynamic therapy in the 9L rat tumour model comparing intravenous and intratumoral administration of the photosensitiser

Autor: Henricus J. C. M. Sterenborg, W. Kamphorst, J.G. Wolbers, Konnie M. Hebeda

Publikováno v: Acta Neurochirurgica, 140, 495-501. Springer Vienna
Acta neurochirurgica, 140(5), 495-501. Springer Wien

In the 9L rat brain tumour model the damage to tumour and normal brain by photodynamic therapy after intratumoural photosensitizer administration (intratumoural PDT) was studied. Twenty four rats received an intratumoural injection of 4 or 40 mm 3 ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3490d9157903791e8f16b69a58d6c101
https://doi.org/10.1007/s007010050131

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Digital imaging of haematoporphyrin derivative distribution in rat brain following intracerebral administration

Autor: J.G. Wolbers, D. P. Noske, Wouter Kamphorst, Henricus J. C. M. Sterenborg

Publikováno v: Lasers In Medical Science. 9:283-290

The distribution of intracerebrally injected HPD in rat brain was analysed by means of a digital imaging system. A technique based on light absorption and optical densitometry was applied for measuring and analysing relative HPD concentrations. Accor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e1e02ac1a4a1bddd7317425396dd267
https://doi.org/10.1007/bf02593891

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Photodynamic therapy of malignant glioma

Autor: J.G. Wolbers, Henricus J. C. M. Sterenborg, D. P. Noske

Publikováno v: Clinical Neurology and Neurosurgery. 93:293-307

Photodynamic therapy is a new form of cancer treatment which can serve as an adjuvant therapy for malignant glioma. It is based on the selective retention of a photosensitive dye in tumour tissue. Subsequent exposure of the tumour to light of an appr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19049bc1216e05fa609f544c2a17a4f3
https://doi.org/10.1016/0303-8467(91)90094-6

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Intra-operative Fluorescence Imaging of ALA-induced PpIX using the Double Ratio Imaging Technique in Malignant Brain Tumours

Autor: Ricardo E. Feller, J.G. Wolbers, Henricus J. C. M. Sterenborg, Armand J. L. Jongen

Publikováno v: Optics and Lasers in Biomedicine and Culture ISBN: 9783642630736

Contrast in fluorescence signals measured in vivo from tumour-selective photosensitizers, is blurred by spatial variations in optical properties of the tissue, its intrinsic fluorescence and geometrical parameters of the fluorescence measurement setu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75375296b5a4fe40dedcdb34de2dd997
https://doi.org/10.1007/978-3-642-56965-4_47

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5-Aminolevulinic acid induced endogenous porphyrin fluorescence in 9L and C6 brain tumours and in the normal rat brain

Autor: Konnie M. Hebeda, Malini Olivo, A.E. Saarnak, J.G. Wolbers, Henricus J. C. M. Sterenborg

Publikováno v: Acta Neurochirurgica, 140, 503-513. Springer Vienna
Acta Neurochirurgica, 140, 503-513
Acta neurochirurgica, 140(5). Springer Wien
Acta Neurochirurgica, 140, pp. 503-513

A new approach in photodynamic therapy is the use of endogenous porphyrins for sensitisation of tumours to light. The induction of endogenous porphyrins after intravenous injection of 5-aminolevulinic acid (ALA, 200 mg kg-1) was studied in 23 rats, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d644e4fc50946206491ee0ba7684d26
https://pure.eur.nl/en/publications/1022f596-1e1f-48fe-b488-35eda5ac1b2e

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FLUORESCENCE LOCALIZATION IN TUMOR AND NORMAL BRAIN AFTER INTRATUMORAL INJECTION OF HEMATOPORPHYRIN DERIVATIVE INTO RAT-BRAIN TUMOR

Autor: H.A.M. van Alphen, M. J. C. Van Gemert, Konnie M. Hebeda, J.G. Wolbers, Henricus J. C. M. Sterenborg, Wouter Kamphorst

Publikováno v: Journal of photochemistry and photobiology. B, Biology, 27(1), 85-92. Elsevier

In the intracerebral 9L rat gliosarcoma, the spatial distribution of the photosensitizer haematoporphyrin derivative (HpD) was studied after intratumoral injection. The fluorescence volume was measured in histological sections from 10 min up to 5 day

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c3c7b03d26281f8a86effba7f4dc69
https://pure.amc.nl/en/publications/fluorescence-localization-in-tumor-and-normal-brain-after-intratumoral-injection-of-hematoporphyrin-derivative-into-ratbrain-tumor(a58a1d6b-7508-43c9-a3ad-ebbc28b4ddac).html

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Spinal subarachnoid hemorrhage due to a filum terminale ependymoma

Autor: P.R. Algra, W. Kamphorst, P. Admiraal, G.J. Hazenberg, J.G. Wolbers

Publikováno v: Clinical neurology and neurosurgery. 94(1)

We present a case of spinal subarachnoid hemorrhage due to an ependymoma of the filum terminale in a 23-year-old male. Clinical signs indicating a spinal origin of the subarachnoid hemorrhage are discussed. Subarachnoid hemorrhages are only rarely ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1a3ce607dd7553304b051eebe8ef69
https://pubmed.ncbi.nlm.nih.gov/1321703

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