Zobrazeno 1 - 10
of 51
pro vyhledávání: '"J.G. Nairn"'
Autor:
J.G. Nairn, M.G. Moldenhauer
Publikováno v:
Journal of Controlled Release. 31:151-162
A nonsolvent/solvent evaporation method of microencapsulation using ethylcellulose and ion-exchange resin-drug complex was used to show that solubility parameters of the microencapsulation system affect the ability of polyisobutylene (PIB) to promote
Autor:
J.G. Nairn, M.G. Moldenhauer
Publikováno v:
Journal of Controlled Release. 22:205-218
A nonsolvent/solvent evaporation method of microencapsulation using ethylcellulose and ion-exchange resin-drug complex was used to show that solubility parameters of the microencapsulation system can be correlated with morphological characteristics a
Autor:
J.G. Nairn, M.G. Moldenhauer
Publikováno v:
Journal of Controlled Release. 17:49-60
The rate of solvent evaporation, during the formation of ethylcellulose microcapsules employing polyisobutylene with theophylline ion-exchange resin as the core material, was found to affect the type of coat formed. The predominantly mononucleated mi
Autor:
S. Motycka, J.G. Nairn
Publikováno v:
Journal of Pharmaceutical Sciences. 68:211-215
Ion-exchange resin beads in the benzoate form were coated by several microencapsulation techniques to alter and improve characteristics, especially the control of drug release, of this type of drug delivery system. The most successful techniques incl
Autor:
S. Motycka, J.G. Nairn
Publikováno v:
Journal of pharmaceutical sciences. 67(4)
Ion-exchange resin beads were coated with various waxes to improve and control their release. The in vitro release rates of benzoate ions from the coated-resin beads were then investigated using a rotating sieve basket technique. The dramatic differe
Publikováno v:
Journal of pharmaceutical sciences. 74(6)
Anion-exchange resin beads in the theophylline form were prepared and coated with paraffin or encapsulated with ethylcellulose by various methods; one of these products was subsequently coated with paraffin in order to achieve a wide range of release
Publikováno v:
Journal of pharmaceutical sciences. 73(1)
A method is presented for encapsulating high molecular weight biological materials such as viral antigen, concanavalin A, and other proteins with cellulose acetate phthalate. The method is simple, inexpensive, and rapid; the process takes approximate
Autor:
J.G. Nairn, R.J. Sawchuk
Publikováno v:
Journal of pharmaceutical sciences. 57(11)
The rate of binding of bilirubin by strongly basic anion-exchange resins was determined by the batch method. The rate of uptake of bilirubin from solution was found to follow a second-order rate expression, and the rate constant was dependent upon th
Publikováno v:
Journal of Investigative Dermatology. 56(2):83-84
The possibility of using a conidial germination test in the evaluation of antifungal chemical was explored using phenol and T. mentagrophytes. The results suggest the feasibility of such a method under carefully controlled conditions. Preventing clum
Publikováno v:
Journal of Pharmaceutical Sciences. 55:1463
An apparatus is described which is useful for the evaluation of adsorption phenomena. The mixing apparatus provides the following features: an inert atmosphere to maintain maximum stability, a smooth, all-glass surface to eliminate spurious adsorptio