Zobrazeno 1 - 10
of 27
pro vyhledávání: '"J.F. Quay"'
Publikováno v:
Drug Development and Industrial Pharmacy. 20:1439-1452
A transdermal patch was developed to circumvent the emesis associated with the oral and intravenous administration of a dopamine agonist, quinelorane, to dogs.Approximate steady-state plasma concentrations were achieved following the daily applicatio
Publikováno v:
Journal of Pharmaceutical Sciences. 74:846-850
A rapid and specific high-performance liquid chromatographic (HPLC) assay has been developed for the determination of enviradene, 1, at concentrations of 2-5 ng/mL in plasma. The drug was extracted from the samples using benzene. The benzene extract
Publikováno v:
Journal of Pharmaceutical Sciences. 59:960-963
Certain surface-active agents placed in a Thomas canine fundic pouch in buffered solutions influence the absorption of soluble drugs (antibiotics). Such agents induce a rapidly reversible hyperabsorptive state of the organ, resulting in blood levels
Autor:
D.R. Holland, J.F. Quay
Publikováno v:
Journal of Pharmaceutical Sciences. 65:417-419
Erythromycin fluxes into rabbit midjejunal segments were studied. When erythromycin was infused into the jugular vein of anesthetized rabbits, the antibiotic was secreted into the segments at a rate of 0.0136 ± 0.0023 mg/min. Preloading of the segme
Publikováno v:
Journal of pharmaceutical sciences. 68(2)
Cinoxacin was measured in plasma and in urine of female mongrel dogs after single 10-mg/kg iv doses. The terminal half-life of plasma cinoxacin was 0.873 hr in dogs whose urine had been alkalinized by oral administration of sodium bicarbonate, 3.79 h
Publikováno v:
Journal of pharmaceutical sciences. 73(11)
The flocculation-deflocculation behavior of cefazolin sodium (I) in nonaqueous media and the effect of surfactants as measured by zeta potential, sedimentation, and porosity were studied. A significant difference in zeta potential was observed when t
Publikováno v:
IEEE transactions on bio-medical engineering. 16(2)
A device is described which provides continuous measurement of transepithelial currents in isolated intestine or other tissues while clamping the transmural potential difference at zero or at a predetermined value. With tissues such as intestine, whe
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