Zobrazeno 1 - 10
of 51
pro vyhledávání: '"J.F. Marier"'
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2497-2509 (2021)
Clinical and Translational Science
Clinical and Translational Science
Teduglutide is a recombinant analog of human glucagon‐like peptide‐2 that regulates the functional and structural integrity of the cells lining the gastrointestinal tract. Teduglutide is approved for the treatment of patients with short bowel syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe7602e37dc517830f0ede82d477beb
https://doaj.org/article/e1ad778fc0454aba88a07040677a1f2e
https://doaj.org/article/e1ad778fc0454aba88a07040677a1f2e
Publikováno v:
Clinical and Translational Science
Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disorder characterized by unpredictable, potentially life-threatening recurrent angioedema attacks. Lanadelumab is a fully human monoclonal antibody with selective binding to active p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17bbd2023f9753096f1f9689ea7ef4c
https://doi.org/10.1111/cts.12806
https://doi.org/10.1111/cts.12806
Publikováno v:
Journal of Clinical Pharmacology
Ontamalimab (SHP647) is a fully human, immunoglobulin G2, antihuman mucosal addressin cell adhesion molecule‐1 (MAdCAM‐1) monoclonal antibody being developed for the treatment of ulcerative colitis (UC) and Crohn's disease (CD). A population phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb5fcceaf0833b54fb027bdde4c9606
https://doi.org/10.1002/jcph.1590
https://doi.org/10.1002/jcph.1590
Autor:
J.F. Marier, Jenna M. Williams, Craig Peterson, Daniel S. Hsia, Nathalie H. Gosselin, Nada Farhat, Robert M. Siegel, Winnie Shih
Publikováno v:
Diabetes, Obesity and Metabolism. 22:480-491
AIMS To assess the pharmacokinetic (PK) and pharmacodynamic characteristics of VI-0521, a fixed-dose combination of immediate-release phentermine (PHEN) and extended-release topiramate (TPM) in adolescents aged 12 to 17 years with obesity, and to rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a4fc400185af35665ce20a68f75cf2
https://doi.org/10.1111/dom.13910
https://doi.org/10.1111/dom.13910
Akademický článek
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Publikováno v:
Journal of Clinical Pharmacology
Elevated bradykinin levels are responsible for the development of clinical symptoms in patients with hereditary angioedema (HAE). Icatibant is a bradykinin type 2 receptor antagonist indicated for the acute treatment of HAE attacks. A population mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0bdb66556f6b949a73ec56796e914d
https://pubmed.ncbi.nlm.nih.gov/33091166
https://pubmed.ncbi.nlm.nih.gov/33091166
Autor:
Sandip Panicker, Christian Schoergenhofer, J.F. Marier, Christa Firbas, Martin Beliveau, James C. Gilbert, Darrell Nix, Johann Bartko, Michael Schwameis, Bernd Jilma, Colin Chang
Publikováno v:
Clinical Pharmacology and Therapeutics
Aberrant activation of the classical complement pathway is the common underlying pathophysiology of orphan diseases such as bullous pemphigoid, antibody‐mediated rejection of organ transplants, cold agglutinin disease, and warm autoimmune hemolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0479ad0b749b2b8fade02ea119ce1d1
https://doi.org/10.1002/cpt.1111
https://doi.org/10.1002/cpt.1111
Autor:
J.F. Marier, Janet B Bautista, Myra L. Patchen, Michele Gargano, Richard Walsh, Paulo S Tioleco, Myra L Flores, Gerardo H Cornelio, Maria E Tamayo, Martin Beliveau, Michael R Kurman
Publikováno v:
Colorectal Cancer. 5:95-108
Aim: Investigate the safety, pharmacokinetics (PK) and efficacy of BTH1677/cetuximab, with and without irinotecan, in patients with metastatic colorectal cancer (mCRC). Patients & methods: Patients with recurrent or progressive mCRC were assigned to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4579745c6630cd11cf9bce5e4970ae2
https://doi.org/10.2217/crc-2016-0010
https://doi.org/10.2217/crc-2016-0010
Autor:
Michael J. Absalon, Nathalie H. Gosselin, Qi Wang, Grygoriy Vasilinin, J.F. Marier, E. Anders Kolb, Todd A. Alonzo, Todd M. Cooper
Publikováno v:
Blood. 136:1-1
CPX-351 (Vyxeos®; daunorubicin and cytarabine liposome for injection), a dual-drug liposomal encapsulation of daunorubicin and cytarabine at a 1:5 synergistic ratio, is approved by the US FDA and EMA for the treatment of adults with newly diagnosed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e81fd58dc56a4dc4aa78d0fda93121a
https://doi.org/10.1182/blood-2020-137163
https://doi.org/10.1182/blood-2020-137163
Autor:
Stefan Faderl, Todd M. Cooper, Qi Wang, Todd A. Alonzo, Nathalie H. Gosselin, E. Anders Kolb, Michael J. Absalon, J.F. Marier
Publikováno v:
Blood. 136:3-3
CPX-351 (Vyxeos®; daunorubicin and cytarabine liposome for injection), a dual-drug liposomal encapsulation of daunorubicin and cytarabine at a synergistic 1:5 molar ratio, is approved by the US FDA and EMA for the treatment of adults with newly diag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::121f5e601b87b482b7f6822a48008056
https://doi.org/10.1182/blood-2020-137205
https://doi.org/10.1182/blood-2020-137205